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SpringerLink电子期刊(15)

在“SpringerLink电子期刊”中，命中：15条，耗时：0.0159964 秒

在所有数据库中总计命中：33条

1. Addition of the p110α inhibitor BYL719 overcomes targeted therapy resistance in cells from Her2-positive-PTEN-loss breast cancer

作者： Chen Zhang ; Bingfei Xu ; Pian Liu

关键词：HER2 ; PTEN ; Breast cancer ; p110α ; p110β

刊名：Tumor Biology

出版年：2016

2. A phase I trial of mFOLFOX6 combined with the oral PI3K inhibitor BKM120 in patients with advanced refractory solid tumors

作者： Autumn J. McRee ; Hanna K. Sanoff ; Cheryl Carlson…

关键词：BKM120 ; PI3K pathway ; 5 ; fluorouracil ; Oxaliplatin ; Gastrointestinal malignancies

刊名：Investigational New Drugs

出版年：2015

3. Parallel phase Ib studies of two schedules of buparlisib (BKM120) plus carboplatin and paclitaxel (q21?days or q28?days) for patients with advanced solid tumors

作者： David M. Hyman ; Alexandra E. Snyder…

关键词：Buparlisib ; PTEN ; Phase Ib ; Carboplatin ; Paclitaxel

刊名：Cancer Chemotherapy and Pharmacology

出版年：2015

4. Laser diode thermal desorption atmospheric pressure chemical ionization tandem mass spectrometry applied for the ultra-fast quantitative analysis of BKM120 in human plasma

作者： Christian Lanshoeft ; Olivier Heudi…

关键词：Laser diode thermal desorption ; Liquid chromatography tandem mass spectrometry ; Salting ; out assisted liquid ; liquid extraction ; Bioanalysis ; Validation ; Pharmacokinetic

刊名：Analytical and Bioanalytical Chemistry

出版年：2014

5. Phase I dose-escalation and -expansion study of buparlisib (BKM120), an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors

作者：Jordi Rodon (1) (11) (2)
Irene Bra?a (1) (2)
Lillian L Siu (3)
Maja J De Jonge (4)
Natasha Homji (5)
David Mills (6)
Emmanuelle Di Tomaso (7)
Celine Sarr (8)
Lucia Trandafir (9)
Cristian Massacesi (9)
Ferry Eskens (4)
Johanna C Bendell (10)

关键词：Buparlisib ; BKM120 ; Oncology ; PI3K inhibitor ; Targeted therapy ; Solid tumors

刊名：Investigational New Drugs

出版年：2014

6. Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone

作者：Yuhuan Zheng (1)
Jing Yang (1)
Jianfei Qian (1)
Liang Zhang (1)
Yong Lu (1)
Haiyan Li (1)
Heather Lin (2)
Yongsheng Lan (1)
Zhiqiang Liu (1)
Jin He (1)
Sungyoul Hong (1)
Sheeba Thomas (1)
Jatin Shah (1)
Veera Baladandayuthapani (2)
Larry W. Kwak (1)
Qing Yi (1) QYi@mdanderson.org

关键词：Multiple myeloma – ; PI3K – ; BKM120 – ; Apoptosis – ; Chemotherapy

刊名：Journal of Molecular Medicine

出版年：2012

7. Hsp90 inhibition enhances PI-3 kinase inhibition and radiosensitivity in glioblastoma

作者：Phyllis R. Wachsberger (1)
Yaacov Richard Lawrence (2)
Yi Liu (1)
Barbara Rice (1)
Nicholas Feo (1)
Benjamin Leiby (1)
Adam P. Dicker (1)

关键词：Glioblastoma ; Hsp90 ; PI3 ; kinase ; HSP990 ; BKM120 ; Radiation therapy

刊名：Journal of Cancer Research and Clinical Oncology

出版年：2014

8. Profound blockade of T cell activation requires concomitant inhibition of different class I PI3K isoforms

作者： Belén Blanco ; Ma Carmen Herrero-Sánchez…

关键词：T lymphocyte ; PI3K inhibitor ; p110 isoform

刊名：Immunologic Research

出版年：2015

9. Effects of PI3K inhibitor NVP-BKM120 on acquired resistance to gefitinib of human lung adenocarcinoma H1975 cells

作者：Yi-chen Liang z/a> (1)
Hong-ge Wu a> (1)
Hong-jian Xue a> (1)
Qing Liu u (1)
Liang-liang Shi AA (1)
Tao Liu u (1)
Gang Wu Ω (1)

关键词：lung adenocarcinoma H1975 cell line ; NVP ; BKM120 ; acquired gefitinib resistance

刊名：Journal of Huazhong University of Science and Technology [Medical Sciences]

出版年：2013

10. The PI3K/AKT/MTOR Signaling Pathway: The Role of PI3K and AKT Inhibitors in Breast Cancer

作者：Florian Huemer (1) (2)
Rupert Bartsch (1) (2)
Michael Gnant (1) (3)

关键词：Cancer ; Breast ; PI3K ; MAPK ; p110 ; AKT ; mTOR ; mTORC1 ; mTORC2 ; Rictor ; Raptor ; PIK3CA ; PTEN ; Resistance ; Feedback ; Crosstalk ; XL147 ; BKM120 ; BYL719 ; BEZ235 ; INK1117 ; MK ; 2206 ; Rapalogue ; Everolimus ; Temsirolimus

刊名：Current Breast Cancer Reports

出版年：2014

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