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ACS电子期刊(8)

在“ACS电子期刊”中，命中：8条，耗时：0.019991 秒

在所有数据库中总计命中：17条

1.Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quino

作者：Felix Gonzalez-Lopez de Turiso ; Xiaolin Hao ; Youngsook Shin ; Minna Bui ; Iain D. G. Campuzano ; Mario Cardozo ; Michelle C. Dunn ; Jason Duquette ; Benjamin Fisher ; Robert S. Foti ; Kirk Henne ; Xiao He ; Yi-Ling Hu ; Ron C. Kelly ; Michael G. Johnson ; Brian S. Lucas ; John McCarter ; Lawrence R. McGee ; Julio C. Medina ; Daniela Metz ; Tisha San Miguel ; Deanna Mohn ; Thuy Tran ; Christine Vissinga ; Sharon Wannberg ; Douglas A. Whittington ; John Whoriskey ; Gang Yu ; Leeanne Zalameda ; Xuxia Zhang ; Timothy D. Cushing

刊名：Journal of Medicinal Chemistry

出版年：2016

2.Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors

作者：Youngsook Shin ; Julia Suchomel ; Mario Cardozo ; Jason Duquette ; Xiao He ; Kirk Henne ; Yi-Ling Hu ; Ron C. Kelly ; John McCarter ; Lawrence R. McGee ; Julio C. Medina ; Daniela Metz ; Tisha San Miguel ; Deanna Mohn ; Thuy Tran ; Christine Vissinga ; Simon Wong ; Sharon Wannberg ; Douglas A. Whittington ; John Whoriskey ; Gang Yu ; Leeanne Zalameda ; Xuxia Zhang ; Timothy D. Cushing

刊名：Journal of Medicinal Chemistry

出版年：2016

3.Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K未 Inhibitors for Inflammation and Autoimmune

作者：Timothy D. Cushing ; Xiaolin Hao ; Youngsook Shin ; Kristin Andrews ; Matthew Brown ; Mario Cardozo ; Yi Chen ; Jason Duquette ; Ben Fisher ; Felix Gonzalez-Lopez de Turiso ; Xiao He ; Kirk R. Henne ; Yi-Ling Hu ; Randall Hungate ; Michael G. Johnson ; Ron C. Kelly ; Brian Lucas ; John D. McCarter ; Lawrence R. McGee ; Julio C. Medina ; Tisha San Miguel ; Deanna Mohn ; Vatee Pattaropong ; Liping H. Pettus ; Andreas Reichelt ; Robert M. Rzasa ; Jennifer Seganish ; Andrew S. Tasker ; Robert C. Wahl ; Sharon Wannberg ; Douglas A. Whittington ; John Whoriskey ; Gang Yu ; Leeanne Zalameda ; Dawei Zhang ; Daniela P. Metz

刊名：Journal of Medicinal Chemistry

出版年：2015

4.Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors

作者：Bernard Barlaam ; Judith Anderton ; Peter Ballard ; Robert H. Bradbury ; Laurent F. A. Hennequin ; D. Mark Hickinson ; Jason G. Kettle ; George Kirk ; Teresa Klinowska ; Christine Lambert-van der Brempt ; Cath Trigwell ; John Vincent ; Donald Ogilvie

刊名：ACS Medicinal Chemistry Letters

出版年：2013

5.Discovery and in Vivo Evaluation of Dual PI3K尾/未 Inhibitors

作者：Felix Gonzalez-Lopez de Turiso ; Youngsook Shin ; Matthew Brown ; Mario Cardozo ; Yi Chen ; David Fong ; Xiaolin Hao ; Xiao He ; Kirk Henne ; Yi-Ling Hu ; Michael G. Johnson ; Todd Kohn ; Julia Lohman ; Helen J. McBride ; Lawrence R. McGee ; Julio C. Medina ; Daniela Metz ; Kent Miner ; Deanna Mohn ; Vatee Pattaropong ; Jennifer Seganish ; Jillian L. Simard ; Sharon Wannberg ; Douglas A. Whittington ; Gang Yu ; Timothy D. Cushing

刊名：Journal of Medicinal Chemistry

出版年：2012

6.Bioactivation of 4-Ipomeanol by CYP4B1: Adduct Characterization and Evidence for an Enedial Intermediate

作者：Brian R. Baer ; Allan E. Rettie ; and Kirk R. Henne

刊名：Chemical Research in Toxicology

出版年：2005

7.Covalent Linkage of Prosthetic Heme to CYP4 Family P450 Enzymes

作者：Kirk R. Henne ; Kent L. Kunze ; Yi-Min Zheng ; Peter Christmas ; Roy J. Soberman ; and Allan E. Rettie

刊名：Biochemistry

出版年：2001

8.Enzymatic Determinants of the Substrate Specificity of CYP2C9: Role of B'-C Loop Residues in Providing the -Stacking Anchor Site for Wa

作者：Robert L. Haining ; Jeffrey P. Jones ; Kirk R. Henne ; Michael B. Fisher ; Dennis R. Koop ; William F. Trager ; and Allan E. Rettie

刊名：Biochemistry

出版年：1999

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2005年(1)

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2000年及以前(1)

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