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在“Elsevier电子期刊”中，命中：684条，耗时：小于0.01 秒

1.Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC₅₀ for a proof-of-principle study

作者：Ahmed S. Abdelsamie^a ; ^b ; Chris J. van Koppen^c ; Emmanuel Bey^c ; Mohamed Salah^a ; Carsten Bö ; rger^d ; Lorenz Siebenbü ; rger^d ; Matthias W. Laschke^e ; Michael D. Menger^e ; Martin Frotscher^a ; ^{m.frotscher@mx.uni-saarland.de}

关键词：17β-Hydroxysteroid dehydrogenase type 1 ; Enzyme inhibitor ; Steroidogenic enzymes ; Estrogen-dependent disease ; Intracrinology

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1

作者：Juliette A. Aka ; Ezequiel-Luis Calvo ; Sheng-Xiang Lin ; ^{Sheng-Xiang.Lin@crchul.ulaval.ca}

关键词：17beta-HSD1 ; Cancer cells ; Estradiol ; Gene expression modulation ; Steroid-deprived medium

刊名：Molecular and Cellular Endocrinology

出版年：2017

3.Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect

作者：Bochra Ben Rhouma^a ; ^{bochra.benrhouma@gmail.com} ; Fakhri Kallabi^a ; Nadia Mahfoudh^b ; Afif Ben Mahmoud^a ; Roger T. Engeli^c ; Hassen Kamoun^d ; Leila Keskes^a ; Alex Odermatt^c ; ^{alex.odermatt@unibas.ch} ; Neila Belguith^a ; ^d

关键词：46 ; XY disorders of sex development ; 17beta-hydroxysteroid dehydrogenase ; Mutation ; HSD17B3 ; Founder effect ; Male sexual development

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

4.Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

作者：Lukas Hroch^a ; ^b ; Patrick Guest^c ; Ondrej Benek^b ; ^d ; Ondrej Soukup^b ; Jana Janockova^b ; Rafael Dolezal^b ; ^d ; ^e ; Kamil Kuca^b ; ^d ; Laura Aitken^c ; Terry K. Smith^c ; Frank Gunn-Moore^c ; Dominykas Zala^c ; Rona R. Ramsay^c ; ; Kamil Musilek^b ; ^d ; ^{kamil.musilek@gmail.com}

关键词：Alzheimer's disease (AD) ; Monoamine oxidase (MAO) ; Amyloid-beta peptide (Aβ) ; Mitochondrial amyloid-binding alcohol dehydrogenase (ABAD) ; 17β-Hydroxysteroid dehydrogenase type 10 (17β-HSD10) ; Horseradish peroxidase (HRP)

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.Prenatal alcohol exposure and prenatal stress differentially alter glucocorticoid signaling in the placenta and fetal brain

作者：N. Lan^a ; ^b ; ^{lanni.lan@gmail.com} ; M.P.Y. Chiu^a ; L. Ellis^a ; J. Weinberg^a

关键词：11β-HSD1 ; 11β-hydroxysteroid dehydrogenase type 1 ; 11β-HSD2 ; 11β-hydroxysteroid dehydrogenase type 2 ; ANOVA ; analysis of variance ; C ; control ; CORT ; corticosterone ; CRH ; corticotropin-releasing hormone ; DOHaD ; developmental origins of health and disease ; GD ; gestation day ; GR ; glucocorticoid receptor ; h ; hour ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal ; mPFC ; medial prefrontal cortex ; MR ; mineralocorticoid receptor ; PAE ; prenatal alcohol exposure ; PF ; pair-fed ; PS ; prenatal stress ; RIA ; rad

刊名：Neuroscience

出版年：2017

6.Slowly progressive d-bifunctional protein deficiency with survival to adulthood diagnosed by whole-exome sequencing

作者：Takashi Matsukawa ; MD ; PhD^a ; ¹ ; Kagari Mano Koshi ; MD^a ; ¹ ; Jun Mitsui ; MD ; PhD^a ; Taro Bannai ; MD^a ; Miho Kawabe ; MD^a ; Hiroyuki Ishiura ; MD ; PhD^a ; Yasuo Terao ; MD ; PhD^a ; Jun Shimizu ; MD ; PhD^a ; Keiko Murayama ; MD^b ; Jun Yoshimura ; PhD^c ; Koichiro Doi ; PhD^c ; Shinichi Morishita ; PhD^c ; Shoji Tsuji ; MD ; PhD^a ; Jun Goto ; MD ; PhD^a ; ^d ; ^{gotoj-tky@umin.ac.jp}

关键词：d-Bifunctional protein deficiency ; HSD17B4 ; Whole-exome sequencing ; Hearing impairment ; Peripheral neuropathy ; Cerebellar ataxia

刊名：Journal of the Neurological Sciences

出版年：2017

7.High mRNA levels of 17β-hydroxysteroid dehydrogenase type 1 correlate with poor prognosis in endometrial cancer

作者：Karlijn M.C. Cornel^a ; ^d ; Camilla Krakstad^b ; ^c ; Bert Delvoux^a ; Sofia Xanthoulea^a ; Balazs Jori^a ; Marlies Y. Bongers^a ; ^d ; Gonda F.J. Konings^a ; Loes F.S. Kooreman^e ; Roy FPM. Kruitwagen^a ; Helga B. Salvesen^c ; ^b ; ENITEC¹

关键词：Endometrial cancer ; 17β-hydroxysteroid-dehydrogenase-type 1 ; 17β-hydroxysteroid-dehydrogenase-type 2 ; Steroid sulphatase ; Estrogen-sulphotransferase ; Aromatase ; Estrogens ; Prognosis

刊名：Molecular and Cellular Endocrinology

出版年：2017

8.CD14⁺⁺ CD16⁻ monocytes are the main source of 11β-HSD type 1 after IL-4 stimulation

作者：Vidya Kunnathully^a ; ^{vid1488@gmail.com} ; Macarena Gomez-Lira^b ; ^{macarena.gomezlira@univr.it} ; Giulio Bassi^c ; ^{giulio.bassi@univr.it} ; Fabio Poli^a ; ^{fabio.poli@univr.it} ; Elisa Zoratti^d ; ^{elisa.zoratti@gmail.com} ; Valentina La Verde^a ; ^{valentina.laverde@gmail.com} ; Luca Idolazzi^a ; ^{luca.idolazzi@univr.it} ; Davide Gatti^a ; ^{davide.gatti@univr.it} ; Ombretta Viapiana^a ; ^{ombretta.viapiana@univr.it} ; Silvano Adami^a ; ^{silvano.adami@univr.it} ; Maurizio Rossini^a ; ^{maurizio.rossini@univr.it}

关键词：CD14 ; CD14++ CD16&minus ; ; CD16 ; CD14+ CD16+ ; ; HTRF ; Homogeneous Time-Resolved Fluorescence ; 11β-HSDs ; 11β-hydroxysteroid dehydrogenases ; CFSE ; carboxyfluorescein-diacetate-succimidyl-ester method ; rMFI ; median fluorescence intensity

刊名：International Immunopharmacology

出版年：2017

9.Rapid and simultaneous determination of piperidinium and pyrrolidinium ionic liquid cations by ion pair chromatography coupled with direct conductivity detection

作者：Xin-Xin Zhang ; Yong-Qiang Liu ; Hong Yu ; ^{yuhonghsd@126.com} ; Ren-Qing Zhang

关键词：Ion-pair chromatography ; Conductivity detection ; Piperidinium ; Pyrrolidinium ; Ionic liquids

刊名：Chinese Chemical Letters

出版年：2017

10.Apparent mineralocorticoid excess and the long term treatment of genetic hypertension

作者：Maryam Razzaghy-Azar^a ; ^b ; Mabel Yau^c ; ^{mabel.yau@mssm.edu} ; Ahmed Khattab^c ; Maria I. New^c

关键词：Low renin hypertension ; 11β-Hydroxysteroid dehydrogenase type 2 ; Spironolactone

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

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