搜索页_+bromodomain

设为首页

收藏本站

网站地图 | English | 公务邮箱

远程访问

NSTL服务站

常用资源

在“Elsevier电子期刊”中，命中：227条，耗时：0.0339832 秒

1.CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation

作者：Heidi Olzscha¹ ; Oleg Fedorov² ; Benedikt M. Kessler³ ; Stefan Knapp² ; ⁴ ; Nicholas B. La Thangue¹ ; ⁵ ; ^{nick.lathangue@oncology.ox.ac.uk}

关键词：acetylation ; aggregation ; amyloid ; bromodomain ; histone deacetylase ; p300 ; CBP ; huntingtin ; proteostasis ; inhibitor

刊名：Cell Chemical Biology

出版年：2017

2.Mutations in the Chromatin Regulator Gene BRPF1 Cause Syndromic Intellectual Disability and Deficient Histone Acetylation

作者：Kezhi Yan¹ ; ¹⁷ ; Justine Rousseau² ; ¹⁷ ; Rebecca Okashah Littlejohn³ ; Courtney Kiss⁴ ; Anna Lehman⁵ ; Jill A. Rosenfeld⁶ ; Constance T.R. Stumpel⁷ ; Alexander P.A. Stegmann⁷ ; Laurie Robak⁶ ; Fernando Scaglia⁶ ; Thi Tuyet Mai Nguyen² ; He Fu² ; Norbert F. Ajeawung² ; Maria Vittoria Camurri² ; Lin Li¹ ; Alice Gardham⁸ ; Bianca Panis⁹ ; Mohammed Almannai⁶ ; Maria J. Guillen Sacoto¹⁰ ; Berivan Baskin¹⁰ ; Claudia Ruivenkamp¹¹ ; Fan Xia⁶ ; Weimin Bi⁶ ; DDD Study¹²

关键词：developmental disorder ; intellectual disability ; epigenetic regulator ; bromodomain ; BRPF2 ; PHD finger ; PWWP domain ; PZP domain ; histone acetylation

刊名：The American Journal of Human Genetics

出版年：2017

3.Lysine acetylation and cancer: A proteomics perspective

作者：Jeovanis Gil ; ^{jeovanis@ccg.unam.mx" class="auth_mail" title="E-mail the corresponding author} ; Alberto Ramí ; rez-Torres ; Sergio Encarnació ; n-Guevara ; ^{encarnac@ccg.unam.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：Lysine acetylation ; Lysine acetyltransferases ; Lysine deacetylases ; Bromodomains ; Cancer ; Proteomics ; Stoichiometry

刊名：Journal of Proteomics

出版年：2017

4.Prenatal nutrition and the risk of adult obesity: Long-term effects of nutrition on epigenetic mechanisms regulating gene expression

作者：Estanislau Navarro^a ; ^{enavarro@idibell.cat} ; ^{estanis.navarro@gmail.com} ; Anna N. Funtikova^b ; ^c ; ^d ; Montserrat Fí ; to^b ; ^e ; Helmut Schrö ; der^b ; ^c

关键词：AS-RNA ; antisense RNA ; BAT ; brown adipose tissue ; BET ; bromodomain and extraterminal ; BMI ; body mass index ; CAD ; coronary artery disease ; CVD ; cardiovascular diseases ; DHA ; docosahexaenoic acid ; DMR ; differentially-methylated region ; DNMTs ; DNA methyltransferases ; DOAD ; developmental origins of adult disease ; DWF ; Dutch Winter Famine ; EGCG ; (&minus ; )-epigallocatechin gallate ; eRNAs ; enhancer RNAs ; ERV ; endogenous retrovirus ; GEN ; genistein ; HAT ; histone acetyl transferase ; HDAC ; histone deacetyl

刊名：The Journal of Nutritional Biochemistry

出版年：2017

5.Inhibition of BET proteins and epigenetic signaling as a potential treatment for osteoporosis

作者：Marc Baud'huin^a ; ^b ; ^c ; ¹ ; Franç ; ois Lamoureux^a ; ^b ; ¹ ; Camille Jacques^a ; ^b ; Lidia Rodriguez Calleja^a ; ^b ; Thibaut Quillard^a ; ^b ; Cé ; line Charrier^a ; ^b ; Jé ; rome Amiaud^a ; ^b ; Martine Berreur^a ; ^b ; Bé ; né ; dicte Brounais-LeRoyer^a ; ^b ; Robert Owen^d ; Gwendolen C. Reilly^d ; James E. Bradner^e ; ^f ; Dominique Heymann^a ; ^b ; ^c ; Benjamin Ory ; PhD^a ; ^b ; ^{Benjamin.ory@univ-nantes.fr} (Associate Professor)

关键词：Osteoporosis ; Epigenetic ; Bromodomain ; Inhibitor ; Osteoblast ; Osteoclast

刊名：Bone

出版年：2017

6.C-terminally truncated constitutively active androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer

作者：Anca Azoitei^a ; Axel S. Merseburger^b ; Beate Godau^b ; M. Raschid Hoda^b ; Evi Schmid^c ; Marcus V. Cronauer^b ; ^{marcus.cronauer@uksh.de}

关键词：aa ; amino-acids ; ADT ; androgen deprivation therapy ; AR ; androgen receptor ; ARΔLBD ; androgen receptor lacking a functional ligand binding domain ; AR-V ; AR splice variant ; BET ; bromodomain and extra-terminal ; CE ; cryptic exon ; CRPC ; castration-resistant prostate cancer ; CTC ; circulating tumor cell ; CTD ; carboxy-terminal domain ; DBD ; DNA-binding domain ; EMT ; epithelial-mesenchymal transition ; FFPE ; formalin-fixed paraffin-embedded ; HR ; hinge region ; I ; intron ; IF ; immunofluorescence ; IGF-1 ; insulin

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

7.Bromodomains: Structure, function and pharmacology of inhibition

作者：Elena Ferri^a ; Carlo Petosa^b ; ^c ; ^d ; Charles E. McKenna^a ; ^{mckenna@usc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Bromodomains ; Acetylated histones ; BET proteins ; Epigenetic drugs ; Drug discovery

刊名：Biochemical Pharmacology

出版年：2016

8.BET bromodomain inhibition reduces maturation and enhances tolerogenic properties of human and mouse dendritic cells

作者：Ronald Schilderink^a ; Matthew Bell^b ; Eleonora Reginato^b ; Chris Patten^b ; Inmaculada" data-ln="Rioja" data-pos="5" data-tb="--> ; Inmaculada Rioja^b ; Francisca W. Hilbers^a ; Pawel A. Kabala^c ; ¹ ; Kris A. Reedquist^c ; ¹ ; David F. Tough^b ; Paul Peter Tak^b ; Rab K. Prinjha^b ; Wouter J. de Jonge^a ; ^{w.j.dejonge@amc.nl}

关键词：HDAC ; histone deacetylase ; BET ; bromodomain and extra-terminal domain ; BMDC ; bone marrow derived DC ; mdDC ; monocyte derived DC ; ALDH ; aldehyde dehydrogenase ; Treg ; regulatory Tcell

刊名：Molecular Immunology

出版年：2016

9.Inhibition of BET bromodomain attenuates angiotensin II induced abdominal aortic aneurysm in ApoE^−/− mice

作者：Qiong Duan^a ; Xiaoxiao Mao^a ; ^b ; ¹ ; Chaonan Liao^c ; ¹ ; Haoyang Zhou^a ; Zelin Sun^a ; Xu Deng^a ; Qiuning Hu^a ; Jun Qi^d ; Guogang Zhang^a ; He Huang^c ; ^{huanghe@csu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jorge Plutzky^b ; ^{jplutzky@rics.bwh.harvard.edu" class="auth_mail" title="E-mail the corresponding author} ; Tianlun Yang^a ; ^{tianluny@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：BET bromodomain ; Aneurysm ; Metalloproteinases ; JQ1

刊名：International Journal of Cardiology

出版年：2016

10.Bromodomain-containing protein 2 induces insulin resistance via the mTOR/Akt signaling pathway and an inflammatory response in adipose tissue

刊名：Cellular Signalling

出版年：2017

按检索点细分(227)

题名(109)

关键词(94)

文摘(173)

按出版年细分(227)

2027年及以后(10)

2017年(8)

2016年(58)

2015年(5)

2013年(11)

2012年(21)

2011年(8)

2010年(4)

2009年(8)

2008年(14)

2007年(12)

2006年(7)

2005年(7)

2004年(13)

2003年(5)

2002年(8)

2001年(6)

2000年(6)

2000年及以前(16)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700