作者：Marcello Arca ; ^{marcello.arca@uniroma1.it}

关键词：Heterozygous familial hypercholesterolemia ; Low-density lipoprotein cholesterol ; Cardiovascular risk ; PCSK9 inhibitors ; Alirocumab ; Evolocumab

刊名：Atherosclerosis

出版年：2017

作者：Robert Dufour^a ; ^{robert.dufour@ircm.qc.ca} ; Jean Bergeron^b ; Daniel Gaudet^c ; Robert Weiss^d ; G. Kees Hovingh^e ; Zhizhi Qing^f ; Feng Yang^g ; Matthew Andisik^g ; Albert Torri^g ; Robert Pordy^g ; Daniel A. Gipe^g

关键词：AE ; adverse event ; Apo ; apolipoprotein ; CVD ; cardiovascular disease ; HDL-C ; high-density lipoprotein cholesterol ; HeFH ; heterozygous familial hypercholesterolemia ; LDL-C ; low-density lipoprotein cholesterol ; Lp(a) ; lipoprotein (a) ; LLT ; lipid-lowering therapy ; MedDRA ; Medical Dictionary for Regulatory Activities ; MI ; myocardial infarction ; PCSK9 ; proprotein convertase subtilisin/kexin type 9 ; Q2W ; every 2  ; weeks ; Q4W ; every 4  ; weeks ; SD ; standard deviation ; TEAE ; treatment-emergent adver

刊名：International Journal of Cardiology

出版年：2017

作者：Michel Farnier^a ; ^{michelfarnier@nerim.net" class="auth_mail" title="E-mail the corresponding author} ; Daniel Gaudet^b ; Velichka Valcheva^c ; Pascal Minini^d ; Kathryn Miller^e ; Bertrand Cariou^f

关键词：Apo ; apolipoprotein ; ASCVD ; atherosclerotic cardiovascular disease ; CKD ; chronic kidney disease ; CV ; cardiovascular ; HDL-C ; high-density lipoprotein cholesterol ; HeFH ; heterozygous familial hypercholesterolemia ; LDL-C ; low-density lipoprotein cholesterol ; LLT ; lipid-lowering therapy ; Lp(a) ; lipoprotein (a) ; Q2W ; every 2  ; weeks ; TEAE ; treatment-emergent adverse event

刊名：International Journal of Cardiology

出版年：2016

作者：Jacqueline L. Cartier ; Anne Carol Goldberg ; ^{agoldber@dom.wustl.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ASCVD ; atherosclerotic cardiovascular disease ; CHD ; coronary heart disease ; CVD ; cardiovascular disease ; CYP ; cytochrome ; EAS ; European Atherosclerosis Society ; FDA ; Food and Drug Administration ; FH ; Familial hypercholesterolemia ; GOF ; gain of function ; HeFH ; heterozygous familial hypercholesterolemia ; HoFH ; homozygous familial hypercholesterolemia ; LDL ; low-density lipoprotein ; LDL-C ; low-density lipoprotein cholesterol ; LDLR ; low-density lipoprotein receptor ; LDLRAP ; low-density lipoprotein re

刊名：Progress in Cardiovascular Diseases

出版年：2016

作者：F. Guaraldi¹ ; M.D. Di Taranto² ; C. Giacobbe³ ; G. Fortunato² ; O. Guardamagna⁴

刊名：Atherosclerosis

出版年：2016

作者：Sophie Bé ; liard ; MD ; PhD^a ; ^b ; ^c ; ^d ; ^{sophie.beliard@ap-hm.fr" class="auth_mail" title="E-mail the corresponding author} ; Auré ; lie Millier ; PhD^e ; Valé ; rie Carreau ; MD^f ; Alain Carrié ; MD ; PhD^g ; Philippe Moulin ; MD ; PhD^h ; Alexandre Fredenrich ; MD ; PhDⁱ ; Michel Farnier ; MD ; PhD^j ; Gé ; rald Luc ; MD ; PhD^k ; David Rosenbaum ; MD^l ; Mondher Toumi ; MD ; PhD^m ; Eric Bruckert ; MD ; PhD^l ; French FH Registry group¹ ; D. Angoulvant ; S. Bé ; liard ; F. Boccara ; E. Bruckert ; V. Durlach ; M. Farnier ; J. Ferriè ; res ; R. Hankard ; M. Krempf ; J.D. Lalau ; G. Luc ; P. Moulin ; F. Paillard ; N. Peretti ; A. Pradignac ; Y. Pucheu ; P. Tounian ; B. Vergès ; O. Ziegler

关键词：Heterozygous familial hypercholesterolemia ; LDL cholesterol ; Cardiovascular risk ; Hypercholesterolemia ; Hyperlipidemia

刊名：Journal of Clinical Lipidology

出版年：2016

作者：Hidenori Arai^a ; ^{harai@ncgg.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Tamio Teramoto^b ; ^{ttera@med.teikyo-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Hiroyuki Daida^c ; ^{daida@juntendo.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Katsunori Ikewaki^d ; ^{kikewaki@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Yuko Maeda^e ; ^{yuko.maeda@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Mariko Nakagomi^e ; ^{mariko.nakagomi@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Masayoshi Shirakawa^e ; Taro Kakikawa^e ; ^{taro.kakikawa@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Hirotaka Numaguchi^e ; ^g ; ^{hiro.numaguchi@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Amy O. Johnson-Levonas^f ; ^{amy_levonas@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Sanskruti Vaidya^f ; ^{sanskruti_vaidya@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Robert O. Blaustein^f ; ^{robert_blaustein@merck.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Anacetrapib ; Low-density lipoprotein cholesterol ; High-density lipoprotein cholesterol ; Cholesteryl ester protein inhibitor ; Heterozygous familial hypercholesterolemia

刊名：Atherosclerosis

出版年：2016

作者：Jean Ferriè ; res ; ⁽¹⁾ ; ^{jean.ferrieres@univ-tlse3.fr" class="auth_mail" title="E-mail the corresponding author} ; Marie-Sophie Combis⁽²⁾ ; Cé ; line Verdier⁽²⁾ ; Anne-Lise Genoux⁽²⁾ ; Isabelle Gennero⁽²⁾ ; Safouane Hamdi⁽²⁾ ; Bertrand Perret⁽²⁾ ; Jean-Bernard Ruidavets⁽³⁾

刊名：Archives of Cardiovascular Diseases Supplements

出版年：2016

作者：Joyce L. Ross ; MSN ; ANP ; CS ; CRNP ; FNLA ; FPCNA ; ^{jlr@joycerossnp.com}

关键词：Children ; Dyslipidemia ; Familial hypercholesterolemia ; HMG-CoA reductase ; Pediatrics ; Statins

刊名：Journal of Pediatric Nursing

出版年：2016

作者：JoAnne M. Foody ; MD ; FACC ; FAHA^a ; ¹ ; ^{joanne.foody@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Raghu Vishwanath ; MSc ; MS ; MBA^b

关键词：Autosomal dominant ; Autosomal recessive ; Familial hypercholesterolemia ; Genotype ; Heterozygote ; Heterozygous ; Homozygote ; Homozygous ; LDL-C level ; Lipid-lowering therapy ; Monogenic ; Phenotype ; Statins

刊名：Journal of Clinical Lipidology

出版年：2016