作者：Lysiane Richert^a ; ^h ; ^{l.richert@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Audrey Baze^a ; ^{a.baze@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Cé ; line Parmentier^a ; ^{c.parmentier@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Helga H.J. Gerets^b ; ^{helga.gerets@ucb.com" class="auth_mail" title="E-mail the corresponding author} ; Rowena Sison-Young^c ; ^{Rowena.Sison-Young@liverpool.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Martina Dorau^d ; ^{Martina.Dorau@sanofi.com" class="auth_mail" title="E-mail the corresponding author} ; Cerys Lovatt^e ; ^{cerys.a.lovatt@gsk.com" class="auth_mail" title="E-mail the corresponding author} ; Andreas Czich^d ; ^{Andreas.Czich@sanofi.com" class="auth_mail" title="E-mail the corresponding author} ; Christopher Goldring^c ; ^{C.E.P.Goldring@liverpool.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; B. Kevin Park^c ; ^{B.K.Park@liv.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Satu Juhila^f ; ^{satu.juhila@orionpharma.com" class="auth_mail" title="E-mail the corresponding author} ; Alison J. Foster^g ; ^{Alison.Foster2@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Dominic P. Williams^g ; ^{Dominic.P.Williams@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author}

关键词：DILI ; drug-induced liver injury ; NPC ; non-parenchymal cells ; 2D-sw ; 2D-sandwich ; SM ; safety margin ; MT ; microtissue ; TC ; training compound

刊名：Toxicology Letters

出版年：2016

作者：Krista A. Zanetti^a ; ¹ ; ^{zanettik@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Zhaoming Wang^b ; ¹ ; ^{wangzha@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Melinda Aldrich^c ; ^d ; ^{melinda.aldrich@Vanderbilt.Edu" class="auth_mail" title="E-mail the corresponding author} ; Christopher I. Amos^e ; ^{Christopher.I.Amos@Dartmouth.edu" class="auth_mail" title="E-mail the corresponding author} ; William J. Blot^c ; ^{blotw@iei.us" class="auth_mail" title="E-mail the corresponding author} ; Elise D. Bowman^f ; ^{bowmane@intra.nci.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Laurie Burdette^b ; ^{burdettl@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Qiuyin Cai^c ; ^{qiuyin.cai@Vanderbilt.Edu" class="auth_mail" title="E-mail the corresponding author} ; Neil Caporaso^b ; ^{caporasn@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Charles C. Chung^b ; ^{chungcc@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Elizabeth M. Gillanders^a ; ^{lgilland@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Christopher A. Haiman^g ; ^{haiman@usc.edu" class="auth_mail" title="E-mail the corresponding author} ; Helen M. Hansen^h ; ^{helen.hansen@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Brian E. Henderson^g ; Laurence N. Kolonelⁱ ; ^{lkolonel@cc.hawaii.edu" class="auth_mail" title="E-mail the corresponding author} ; Loic Le Marchandⁱ ; ^{Loic@cc.hawaii.edu" class="auth_mail" title="E-mail the corresponding author} ; Shengchao Li^b ; ^{shengchao.li@nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Lorna Haughton McNeill^j ; ^{lmcneill@mdanderson.org" class="auth_mail" title="E-mail the corresponding author} ; Brí ; d M. Ryan^f ; ^{ryanb@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Ann G. Schwartz^k ; ^{schwarta@karmanos.org" class="auth_mail" title="E-mail the corresponding author} ; Jennette D. Sison^h ; ^{jennette.sison@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Margaret R. Spitz^l ; ^{spitz@bcm.edu" class="auth_mail" title="E-mail the corresponding author} ; Margaret Tucker^b ; ^{tuckerp@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Angela S. Wenzlaff^k ; ^{wenzlaff@karmanos.org" class="auth_mail" title="E-mail the corresponding author} ; John K. Wiencke^h ; ^{john.wiencke@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Lynne Wilkensⁱ ; ^{lynne@cc.hawaii.edu" class="auth_mail" title="E-mail the corresponding author} ; Margaret R. Wrensch^h ; ^{Margaret.Wrensch@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Xifeng Wu^m ; ^{xwu@mdanderson.org" class="auth_mail" title="E-mail the corresponding author} ; Wei Zheng^c ; ^{wei.zheng@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Weiyin Zhou^b ; ^{zhouw@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; David Christianiⁿ ; ^{dchris@hsph.harvard.edu" class="auth_mail" title="E-mail the corresponding author} ; Julie R. Palmer^o ; ^{jpalmer@bu.edu" class="auth_mail" title="E-mail the corresponding author} ; Trevor M. Penning^p ; ^q ; ^{PENNING@UPENN.EDU" class="auth_mail" title="E-mail the corresponding author} ; Alyssa G. Rieber^r ; ^{arieber@mdanderson.org" class="auth_mail" title="E-mail the corresponding author} ; Lynn Rosenberg^o ; ^{lrosenbe@bu.edu" class="auth_mail" title="E-mail the corresponding author} ; Edward A. Ruiz-Narvaez^o ; ^{eruiznar@bu.edu" class="auth_mail" title="E-mail the corresponding author} ; Li Suⁿ ; ^{lisu@hsph.harvard.edu" class="auth_mail" title="E-mail the corresponding author} ; Anil Vachani^p ; ^s ; ^{avachani@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Yongyue Weiⁿ ; ^{ywei@hsph.harvard.edu" class="auth_mail" title="E-mail the corresponding author} ; Alexander S. Whitehead^p ; ^q ; ^{aswhiteh@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Stephen J. Chanock^b ; ¹ ; ^{chanocks@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Curtis C. Harris^f ; ¹ ; ^{Curtis_Harris@nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：Genome-wide association study ; Lung neoplasms ; Smoking ; African Americans ; Telomerase ; Receptors ; Cholinergic

刊名：Lung Cancer

出版年：2016

作者：Xiangrong Kong ; PhD¹ ; ² ; Rupert W. Strauss ; MD¹ ; ³ ; ⁴ ; Michel Michaelides ; MD³ ; Artur V. Cideciyan ; PhD⁵ ; José ; -Alain Sahel ; MD⁶ ; Beatriz Muñ ; oz ; MS¹ ; Sheila West ; PhD¹ ; Hendrik P.N. Scholl ; MD ; MA¹ ; ^{hscholl1@jhmi.edu" class="auth_mail" title="E-mail the corresponding author} ; for the ProgStar Study Group^&lowast ; ; Hendrik P.N. Scholl ; Rupert W. Strauss ; Yulia Wolfson ; Millena Bittencourt ; Syed Mahmood Shah ; Mohammed Ahmed ; Etienne Schonbach ; Kaoru Fujinami ; Elias Traboulsi ; Justis Ehlers ; Meghan Marino ; Susan Crowe ; Rachael Briggs ; Angela Borer ; Anne Pinter ; Tami Fecko ; Nikki Brugnoni ; Janet S. Sunness ; Carol Applegate ; Leslie Russell ; Michel Michaelides ; Anthony Moore ; Andrew Webster ; Sophie Connor ; Victoria McCudden ; Maria Pefkianaki ; Jonathan Aboshiha ; Gerald Liew ; Graham Holder ; Anthony Robson ; Alexa King ; Daniela Ivanova Cajas Narvaez ; Katy Barnard ; Catherine Grigg ; Hannah Dunbar ; Yetunde Obadeyi ; Karine Girard-Claudon ; Hilary Swann ; Avani Rughani ; Charles Amoah ; Dominic Carrington ; Kanom Bibi ; Emerson Ting Co ; Andrew Carter ; Anne Georgiou ; Selma Lewis ; Saddaf Shaheen ; Harpreet Shinmar ; Linda Burton ; Paul Bernstein ; Kimberley Wegner ; Briana Lauren Sawyer ; Bonnie Carlstrom ; Kellian Farnsworth ; Cyrie Fry ; Melissa Chandler ; Glen Jenkins ; Donnel Creel ; David Birch ; Yi-Zhong Wang ; Luis Rodriguez ; Kirsten Locke ; Martin Klein ; Paulina Mejia ; Artur V. Cideciyan ; Samuel G. Jacobson ; Sharon B. Schwartz ; Rodrigo Matsui ; Michaela Gruzensky ; Alejandro J. Roman ; Eberhart Zrenner ; Fadi Nasser ; Gesa Astrid Hahn ; Barbara Wilhelm ; Tobias Peters ; Benjamin Beier ; Tilman Koenig ; Susanne Kramer ; José ; -Alain Sahel ; Saddek Mohand-Said ; Isabelle Audo ; Caroline Laurent-Coriat ; Ieva Sliesoraityte ; Christina Zeitz ; Fiona Boyard ; Minh Ha Tran ; Mathias Chapon ; Cé ; line Chaumette ; Juliette Amaudruz ; Victoria Ganem ; Serge Sancho ; Aurore Girmens ; Hendrik P.N. Scholl ; Rupert W. Strauss ; Yulia Wolfson ; Syed Mahmood Shah ; Mohammed Ahmed ; Etienne Schonbach ; Robert Wojciechowski ; Shazia Khan ; David G. Emmert ; Dennis Cain ; Mark Herring ; Jennifer Bassinger ; Lisa Liberto ; Sheila West ; Ann-Margret Ervin ; Beatriz Munoz ; Xiangrong Kong ; Kurt Dreger ; Jennifer Jones ; Srinivas Sadda ; Anamika Jha ; Alex Ho ; Brendan Kramer ; Amirhossein Hariri ; Gloria Rebecca Blanquel ; Ngoc Lam ; Sean Pitetta ; Yue Shi ; Rita Tawdros ; Christine Petrossian ; Dennis Jenkins ; Muneeswar Gupta ; Yong Dong Zhou ; Katherine Aguilar ; Cynthia Chan ; Lisa Santos ; Brian Seo ; Christopher Sison ; Silvia Perez ; Stephanie Chao ; Kelly Miyasato ; Julia Higgins ; Zoila Luna ; Anita Menchaca ; Norma Gonzalez ; Vicky Robledo ; Karen Carig ; Kirstie Baker ; David Ellenbogen ; James Russell ; Daniel Bluemel ; Alex Moreno ; Royal Pham ; Theo Sanford ; Daisy Linares ; Mei Tran

关键词：BPC VA ; best or presenting VA with correction ; CRF ; clinical report form ; GEE ; generalized estimating equation ; IQR ; interquartile range ; LMM ; linear mixed effects model ; logMAR ; logarithm of the minimum angle of resolution ; STGD1 ; Stargardt macular dystrophy 1 ; VA ; visual acuity ; VI ; visual impairment

刊名：Ophthalmology

出版年：2016

作者：Neil R. Kitteringham ; Azman Abdullah ; Joanne Walsh ; Laura R ; le ; Rosalind E. Jenkins ; Rowena Sison ; Christopher E.P. Goldring ; Helen Powell ; Christopher S ; erson ; Samantha Williams ; Larry Higgins ; Masay

关键词：Nrf2 ; Transgenic ; Liver ; Protein expression ; iTRAQ ; Lipid metabolism

刊名：Journal of Proteomics

出版年：2010