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在“Elsevier电子期刊”中，命中：45条，耗时：0.0789628 秒

在所有数据库中总计命中：523条

1.Antibody engineering of a cytotoxic monoclonal antibody 84 against human embryonic stem cells: Investigating the effects of multivalency on cytotoxicity

作者：Maximilian Klement^a ; ^b ; Jiyun Zheng^a ; ^c ; Chengcheng Liu^a ; Heng-Liang Tan^a ; Victor Vai Tak Wong^a ; Andre Boon-Hwa Choo^a ; ^d ; Dong-Yup Lee^a ; ^b ; ^e ; ^{cheld@nus.edu.sg} ; Dave Siak-Wei Ow^a ; ^{dave_ow@bti.a-star.edu.sg} ; ^{dave_ow@yahoo.com}

关键词：BSA ; bovine serum albumine ; EB ; embryoid body ; Fab ; fragment antigen binding ; hESC ; human embryonic stem cells ; HPLC ; high-pressure liquid chromatograpy ; HRP ; horseradish peroxidase ; IgG ; immunoglobulin G ; IgM ; immunoglobulin M ; IPTG ; isopropyl β -d-1-thiogalactopyranoside ; mAb ; monoclonal antibody ; PEG ; polyethylene glycol ; PODXL-1 ; podocalaxin like protein-1 ; scFv ; single chain fragment variable ; SEC ; size-exclusion chromatography ; ZIP ; GCN4 Leucine Zipper

刊名：Journal of Biotechnology

出版年：2017

2.Mixed PEGylated surfactant modifying system decrease the accelerated blood clearance phenomenon of nanoemulsions in rats

作者：Yuqing Su^a ; Wenya Tang^b ; Yanzhi Song^a ; Chunling Wang^a ; Qingjing Tian^a ; Xuling Wang^a ; Jingjing Quan^a ; Buoqun Li^a ; Shaoning Wang^c ; ^{wsn-xh@126.com} ; Yihui Deng^a ; ^{pharmdeng@gmail.com}

关键词：Accelerated blood clearance (ABC) phenomenon ; Repeated administration ; 4-arm PEG5000-CHMA ; Anti-PEG IgM

刊名：Asian Journal of Pharmaceutical Sciences

出版年：2017

3.Exploring the relationship between anti-PEG IgM behaviors and PEGylated nanoparticles and its significance for accelerated blood clearance

作者：Kouichi Shiraishi^a ; Kumi Kawano^b ; Yoshie Maitani^b ; Taiki Aoshi^c ; ^d ; ^e ; Ken J. Ishii^c ; ^d ; Yusuke Sanada^f ; Shinichi Mochizuki^f ; Kazuo Sakurai^f ; Masayuki Yokoyama^a ; ^{masajun2093ryo@jikei.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Anti-PEG IgM antibody ; PEG-liposomes ; Polymeric micelles ; Accelerated blood clearance (ABC) phenomenon ; Hydrophobicity of conjugates

刊名：Journal of Controlled Release

出版年：2016

4.Impact of anti-PEG IgM antibodies on the pharmacokinetics of pegylated asparaginase preparations in mice

作者：Sabine M. Poppenborg^a ; ^{s.poppenborg@medac.de" class="auth_mail" title="E-mail the corresponding author} ; Julia Wittmann^b ; ^{j.wittmann@celares.com" class="auth_mail" title="E-mail the corresponding author} ; Wolfgang Walther^c ; ^{Wolfgang.Walther@epo-berlin.com" class="auth_mail" title="E-mail the corresponding author} ; Gunda Brandenburg^a ; ^{g.brandenburg@medac.de" class="auth_mail" title="E-mail the corresponding author} ; Ralf Krä ; hmer^b ; ^{r.kraehmer@celares.com" class="auth_mail" title="E-mail the corresponding author} ; Joachim Baumgart^a ; ^{j.baumgart@medac.de" class="auth_mail" title="E-mail the corresponding author} ; Frank Leenders^b ; ^{f.leenders@celares.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ALL ; acute lymphoblastic leukemia ; ASNase ; l-asparaginase ; AUC ; area under the curve ; CL ; total plasma clearance ; ELISA ; enzyme-linked immunosorbent assay ; PD ; pharmacodynamics ; PEG-rASNase ; pegylated recombinant E. colil-Asparaginase ; PEG ; polyethylene glycol ; PK ; pharmacokinetics

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

5.Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus

作者：Christine E. Henry^b ; Ying-Ying Wang^d ; Qi Yang^a ; Thuy Hoang^e ; Sumon Chattopadhyay^f ; Timothy Hoen^d ; Laura M. Ensign^f ; ^g ; Kenetta L. Nunn^b ; Holly Schroeder^a ; Justin McCallen^a ; Thomas Moench^h ; Richard Cone^d ; Steve R. Rofflerⁱ ; Samuel K. Lai^a ; ^b ; ^c ; ^{lai@unc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：PEGylation ; IgG ; IgM ; Mucosal immunity ; Nanomedicine ; Diffusion

刊名：Acta Biomaterialia

出版年：2016

6.Immunogenicity of long-lasting recombinant factor VIII products

作者：Mathieu Ing^a ; ^b ; ^c ; Nimesh Gupta^d ; Maud Teyssandier^a ; ^b ; ^c ; Bernard Maillè ; re^e ; Marc Pallardy^f ; Sandrine Delignat^a ; ^b ; ^c ; Sé ; bastien Lacroix-Desmazes^a ; ^b ; ^c ; ^{sebastien.lacroix-desmazes@crc.jussieu.fr" class="auth_mail" title="E-mail the corresponding author} ; on behalf of the ABIRISK consortium

关键词：APC ; antigen-presenting cells ; BcR ; B cell receptor ; EMA ; European Medicines Agency ; Fc ; crystallizable fragment ; FcγR ; receptor for IgG Fc portion ; FcRn ; neonatal Fc receptor ; FVIIa ; activated factor VII ; FVIII ; factor VIII ; GLP-1 ; glucagon-like peptide 1 ; HA1 ; hemagglutinin ; HSA ; human serum albumin ; IgG ; immunoglobulin G ; IgM ; immunoglobulin M ; LRP-1 ; lipoprotein receptor protein 1 ; MHC ; major histocompatibility complex ; PEG ; polyethylene glycol ; PTPs ; previously treated patients ; PUPs ; previ

刊名：Cellular Immunology

出版年：2016

7.Epstein-Barr virus and Interleukin-28B polymorphism in the prediction of response to interferon therapy in hepatitis C patients

作者：Abdel-Rahman N. Zekri^a ; ^{ncizekri@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Dina Abdullah^a ; Ahmed Osman^b ; Mahmoud N. El-Rouby^a ; Naglaa Zayed^c ; Gamal Esmat^c ; Wafaa Elakel^c ; Hanan Abdel Hafez^c

关键词：AFP ; α-fetoprotein ; BNLF1 ; BamHI N Leftward Frame 1 ; BZLF1 ; BamHI Z Leftward Frame 1 ; EBER2 ; EBV-encoded small nuclear RNA 2 ; EBNA ; Epstein&ndash ; Barr nuclear antigen ; EBV ; Epstein&ndash ; Barr virus ; FUP ; follow-up ; HCV ; hepatitis C virus ; IFN ; interferon ; IL-28B ; Interleukin 28B ; IQR ; interquartile range ; NR ; nonresponder ; PEG-IFN ; pegylated interferon ; SVR ; sustained virological response ; VCA ; viral capsid antigen

刊名：Arab Journal of Gastroenterology

出版年：2015

8.B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice

作者：Yosuke Hashimoto^a ; Amr S. Abu Lila^a ; ^b ; Taro Shimizu^a ; Tatsuhiro Ishida^a ; ^{ishida@tokushima-u.ac.jp" class="auth_mail} ; Hiroshi Kiwada^a

关键词：ABC ; accelerated blood clearance ; BCR ; B cell receptor ; CHOL ; cholesterol ; DC ; dendritic cells ; DC-6-14 ; O ; O&prime ; -ditetradecanoyl-N-(伪-trimethyl ammonio acetyl) diethanolamine chloride ; DOPE ; 1 ; 2-dioleoyl-sn-glycero-3-phosphoethanolamine ; ELISA ; enzyme-linked immunosorbent assay ; FITC ; fluorescein isothiocyanate ; HEPC ; hydrogenated egg phosphatidylcholine ; IFN-伪 ; interferon alpha ; IFN-纬 ; interferon gamma ; IL-6 ; interleukin 6 ; mPEG2000-DSPE ; 1 ; 2-distearoyl-sn-glycero-3-phosphoethanolamine-n-[me

刊名：Journal of Controlled Release

出版年：28 June 2014

9.Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs

作者：Yosuke Hashimoto^a ; Taro Shimizu^a ; Yu Mima^a ; Amr S. Abu Lila^a ; ^b ; Tatsuhiro Ishida^a ; ^{ishida@tokushima-u.ac.jp" class="auth_mail} ; Hiroshi Kiwada^a

关键词：ABC ; accelerated blood clearance ; BSA ; bovine serum albumin ; CHOL ; cholesterol ; CL ; conventional liposome ; EDTA ; ethylene diaminetetra-acetic acid ; ELISA ; enzyme-linked immunosorbent assay ; EPR ; enhanced permeability and retention ; FBS ; fetal bovine serum ; FDA ; food and drug administration ; HEPC ; hydrogenated egg phosphatidylcholine ; HRP ; horseradish peroxidase ; mPEG2000-DSPE ; 1 ; 2-distearoyl-sn-glycero-3-phosphoethanolamine-n-[methoxy(polyethylene glycol)-2000] ; OVA ; egg white albumin ; PEG ; poly

刊名：Toxicology and Applied Pharmacology

出版年：15 May, 2014

10.Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA

作者：Tatsuaki Tagami¹ ; ^a ; Yumi Uehara^a ; Naoto Moriyoshi^a ; Tatsuhiro Ishida ; ^a ; ^{ishida@ph.tokushima-u.ac.jp"" rel=""nofollow} ; Hiroshi Kiwada^a

关键词：Accelerated blood clearance (ABC) phenomenon ; Polyethylene glycol (PEG) ; Anti-PEG IgM ; Small interfering RNA (siRNA) ; 2′ ; -O-methyl-uridine modified siRNA (2′ ; -OMe siRNA)

刊名：Journal of Controlled Release

出版年：2011

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