“奇病”论彭州地震前后出生缺陷的比较研究
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摘要
目的:利用付出沉重代价的5.12地震资源,研究地震后新生儿出生缺陷率的增长趋势。方法:充分收集汶川大地震重灾区彭州市新生儿出生缺陷资源,运用地震后的出生缺陷73例,与该市地震前的88例做比较分析。结果:该市震后出生缺陷率平均水平比震前增长了2.9‰,尤其是震时己孕3个月以内、震后再孕者,分别增长了4.6‰、5.9‰。出生缺陷的种类变化还看不出规律,尚待进一步研究。讨论:地震等灾害事件应特别重视妇幼保健,面对出生缺陷增长的严峻数据,结合中医"奇病"观,深入分析灾害对妊娠3个月"质"与"量"的影响,寻找积极有效的预防措施。
Objective:To use the 5.12 earthquake in resources of pay a heavy price after the earthquake,study the rate of birth defects in the growth trend.Methods:To full collection the resources birth defects in Pengzhou of the hardest hit Wenchuan earthquake,and use of birth defects after the earthquake of 73 cases,to do the comparative analysis with the city 88 cases before the earthquake.Results:After the earthquake the city's rate of birth defects than the average pre-shock increase of 2.9‰,in particular,when the shock has been less than 3 months pregnant,pregnant after shock,increase of 4.6‰,5.9‰ respectively.The types of birth defects also do not see the law change,pending further study.Conclusion:Earthquake disaster events should pay special attention to maternal and child health,growth in the face of severe birth defects data,combined with traditional Chinese medicine "odd disease" concept,in-depth analysis of disasters on the pregnancy in March of "quality" and "quantity" of the impact of an active search for effective preventive measures.
Objective:To use the 5.12 earthquake in resources of pay a heavy price after the earthquake,study the rate of birth defects in the growth trend.Methods:To full collection the resources birth defects in Pengzhou of the hardest hit Wenchuan earthquake,and use of birth defects after the earthquake of 73 cases,to do the comparative analysis with the city 88 cases before the earthquake.Results:After the earthquake the city's rate of birth defects than the average pre-shock increase of 2.9‰,in particular,when the shock has been less than 3 months pregnant,pregnant after shock,increase of 4.6‰,5.9‰ respectively.The types of birth defects also do not see the law change,pending further study.Conclusion:Earthquake disaster events should pay special attention to maternal and child health,growth in the face of severe birth defects data,combined with traditional Chinese medicine "odd disease" concept,in-depth analysis of disasters on the pregnancy in March of "quality" and "quantity" of the impact of an active search for effective preventive measures.
引文
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[2]韦云,谭圣娥.从中医脏腑看心理应激[J].中医中药,2008,3(5):232-233.
[3]李天心.医学心理学[M].北京:北京医科大学和协和医科大学联合出版社,1998.
[4]王米渠,吴斌,冯韧.“恐伤肾”母子两代的生理研究[J].福建中医药,2003,1(34):3-4.
[5]Maccaria S,Darnauderya M,Morley F S,et al.Prenatal stress and long-term consequences:implications of glucocorticoid hormones[J].Neuroscience and Biobehavioral Reviews,2003,27:119-127.
[6]Schneider ML,Roughton E C,Koehler AJ,et al.Growth developmentfollowing prenatal stress exposure in primates:an examination of on-togenetic vulnerability[J].Child Dev,1999,70:263-274.
[7]Huizink AC.Prenatal stress and its effects on infant development[J].Academic Thesis University Utrecht The Netherlands,2000:1-217.
[8]Perkins AV,Linton E A,Eben F,et al.Corticotrophin-releasing hor-mone[J].Early Human Development,2002,70:3-14.
[9]Hansen D,Lou HC,Olsen J.Serious life events and congenital malfor-mations:a national study with complete follow-up[J].Lancet,2000,356:875-880.
[10]Smith J W,Seckl J R,Evans A T,et al.Gestational stress inducespost-partum depression-like behaviour and alters maternal care inrats[J].Psychoneuroendocrinology,2004,29:227-244.
[11]李妍,侯丽辉,吴效科.中医肾主生殖理论探讨及现代研究进展[J].世界中西医结合杂志,2008,9(3):557-559.
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