Cu-Catalyzed Three-Component Coupling of Aryne, Alkyne, and Benzenesulfonothioate: Modular Synthesis of o-Alkynyl Arylsulfides

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• 作者：Xianglong Peng ; Chen Ma ; Chen-Ho Tung ; Zhenghu Xu
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：September 2, 2016
• 年：2016
• 卷：18
• 期：17
• 页码：4154-4157
• 全文大小：376K
• 年卷期：0
• ISSN：1523-7052

文摘

A copper-catalyzed three-component coupling reaction of in situ formed arynes, terminal alkynes, and benzenesulfonothioates is described. This reaction provides an efficient modular synthesis of o-alkynyl arylsulfides from easily available starting materials. This process involves one C–S bond and one C–C bond formation in one pot.