δ-Opioid receptors: Pivotal role in intermittent hypoxia-augmentation of cardiac parasympathetic control and plasticity
详细信息 查看全文
- 作者：Juan A. Estrada ; Mathew A. Barlow1 ; Darice Yoshishige ; Arthur G. Williams Jr. ; H. Fred Downey ; Robert T. Mallet ; Robert.Mallet@unthsc.edu" class="auth_mail" title="E-mail the corresponding author ; James L. Caffrey
- 关键词：AR ; adrenergic receptor ; ChT-1 ; choline transporter-1 ; IHT ; intermittent hypoxia training ; OR ; opioid receptor ; ROS ; reactive oxygen species ; TH ; tyrosine hydroxylase ; VAChT ; vesicular acetylcholine transporter
- 刊名：Autonomic Neuroscience: Basic and Clinical
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：198
- 期：Complete
- 页码：38-49
- 全文大小：2393 K
文摘
- •
IHT induced cardioprotection is associated with an improved autonomic profile.
- •
IHT augments vagally mediated bradycardia.
- •
Vagotonic δ1-OR activity is enhanced by IHT at the expense of competing vagolytic δ2-OR activity.
- •
IHT induces parasympathetic nerve growth in myocardium.
- •
Adrenergic influence over the heart is attenuated by IHT.