Interaction between amphipathic triblock copolymers and L-α-dipalmitoyl phosphatidylcholine large unilamellar vesicles
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- 作者：M.A. Palominosa ; D. Vilchesa ; E. Bosselb ; M.A. Soto-Arriaza ; Dr.a ; c ; marcosoto@uc.cl" class="auth_mail" title="E-mail the corresponding author
- 关键词：PCL ; poly(ε-caprolactone) ; PEO ; poly(ethylene oxide) ; COP1 ; PCL12&ndash ; PEO45&ndash ; PCL12 ; COP2 ; PCL16&ndash ; PEO104&ndash ; PCL16 ; DPH ; 1 ; 6-diphenyl-1 ; 3 ; 5-hexatriene ; GP ; Generalized Polarization ; Laurdan ; 2-dimethylamino-6-lauroylnaphthalene ; DMSO ; dimethyl sulfoxide ; LUVs ; large unilamellar vesicles ; DPPC ; L-α-dipalmitoyl-sn-glycero-3-phosphocholine ; CMC ; critical micelle concentration
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 December 2016
- 年：2016
- 卷：148
- 期：Complete
- 页码：30-40
- 全文大小：1417 K
文摘
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Triblock copolymers interact with DPPC large unilamellar vesicles.
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Both copolymers increase the main phase transition temperature.
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COP2 affects the interface and the inner part of the bilayer.
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COP2 decreases water permeability through the lipid bilayer.
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Copolymers decrease calcein permeability at higher concentration.