Experimental and theoretical study of quercetin complexes formed on pure silica and Zn-modified mesoporous MCM-41 and SBA-16 materials
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- 作者：Margarita Popovaa ; mpopova@orgchm.bas.bg" class="auth_mail" title="E-mail the corresponding author ; Ivalina Trendafilovaa ; Á ; gnes Szegedib ; Judith Mihá ; lyb ; Pé ; ter Né ; methb ; Sylvia G. Marinovac ; d ; Hristiyan A. Aleksandrovc ; Georgi N. Vayssilovc
- 关键词：ZnSBA-16 ; ZnMCM-41 ; Surface modification ; Quercetin ; Delivery systems ; Dermal formulations ; DFT
- 刊名：Microporous and Mesoporous Materials
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：228
- 期：Complete
- 页码：256-265
- 全文大小：1595 K
文摘
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High loading of quercetin on initial and Zn-modified MCM-41 and SBA-16 carriers.
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The quercetin molecule is adsorbed to the silanol groups and/or the Zn2+ cations of the carriers.
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The stable Zn-quercetin complex on the zinc modified supports was registered.
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Faster quercetin release from pure MCM-41 and SBA-16 carriers in buffer at pH = 5.5