PTTG1, A novel androgen responsive gene is required for androgen-induced prostate cancer cell growth and invasion

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• 作者：Zheng Zhang^a ; ¹ ; Bo Jin^b ; ¹ ; Yaqiong Jin^c ; Shengquan Huang^a ; Xiaohua Niu^a ; Zebin Mao^d ; Dianqi Xin^a ; ^{xin-dianqi@163.com}
• 关键词：PTTG1 ; Prostate cancer ; Androgen responsive gene
• 刊名：Experimental Cell Research
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：350
• 期：1
• 页码：1-8
• 全文大小：897 K
• 卷排序：350

文摘

Androgen treatment of LNCaP cells induced PTTG1 expression. Knockdown of PTTG1 expression significantly reduced androgen-induced LNCaP cell growth and invasion. PTTG1 is highly expressed in metastasis prostate cancer tissue. PTTG1 is a novel downstream target gene of androgen receptor.