Programmed Death 1 Expression on CD4+ T Cells Predicts Mortality after Allogeneic Stem Cell Transplantation
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- 作者：Henning Schade1 ; 2 ; Sharon Sen1 ; 3 ; C. Preston Neff3 ; Brian M. Freed1 ; 3 ; Dexiang Gao4 ; Jonathan A. Gutman1 ; 2 ; &dagger ; ; Brent E. Palmer1 ; 3 ; &dagger ; ; brent.palmer@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Programmed death 1 (PD-1) expression ; CD4+ T cells ; Allogeneic stem cell transplantation ; Cord blood
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：22
- 期：12
- 页码：2172-2179
- 全文大小：1365 K
文摘
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Programmed death 1 expression on CD4+ T cells after stem cell transplantation is elevated, independent of donor type
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In nonsurvivors, programmed death 1 expression is higher compared with survivors
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Programmed death 1 expression is elevated in nonsurvivors, independent of donor type
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T central memory and T effector memory cells show elevated PD-1 expression in nonsurvivors