Discoveries, metabolic roles and diseases of mitochondrial carriers: A review
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- 作者：Ferdinando Palmieria ; ferdpalmieri@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Magnus Monné ; a ; b
- 关键词：AAC ; ADP/ATP carrier ; CoA ; coenzyme A ; EPRA method ; expression-purification-reconstitution-assay method ; MC ; mitochondrial carrier ; MCF ; mitochondrial carrier family ; Pi ; phosphate
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：1863
- 期：10
- 页码：2362-2378
- 全文大小：1982 K
文摘
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Mitochondrial carriers (MCs) form a superfamily of intracellular membrane transporters.
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The diverse substrates of MCs are vital in many intra- and extra-mitochondrial processes.
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Over 50 MCs have been identified and characterized by a gene-to-function approach.
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The known MC-associated diseases demonstrate their physiological importance.