A cell culture-derived whole virus influenza A vaccine based on magnetic sulfated cellulose particles confers protection in mice against lethal influenza A virus infection

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• 作者：Michael M. Pieler^a ; ¹ ; ^{pieler@mpi-magdeburg.mpg.de} ; Sarah Frentzel^b ; ¹ ; ^{sarah.frentzel@med.ovgu.de} ; Dunja Bruder^b ; ^c ; ^{dunja.bruder@med.ovgu.de} ; Michael W. Wolff^a ; ^d ; ^{mwolff@mpi-magdeburg.mpg.de} ; Udo Reichl^a ; ^d ; ^{ureichl@mpi-magdeburg.mpg.de}
• 关键词：Influenza ; Vaccination ; Purification ; Magnetic particles ; Formulation ; Immunization
• 刊名：Vaccine
• 出版年：2016
• 出版时间：7 December 2016
• 年：2016
• 卷：34
• 期：50
• 页码：6367-6374
• 全文大小：550 K
• 卷排序：34

文摘

Vaccine purification and formulation with magnetic sulfated cellulose particles (MSCP). Influenza A virus MSCP vaccine for immunization of mice against lethal challenge. Purification and formulation of low-cost veterinary vaccines. Fast and simple purification for screening studies. Purification of viral vectors for gene therapy.