Homeostatic effects of exercise and sleep on metabolic processes in mice with an overexpressed skeletal muscle clock

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• 作者：Allison J. Brager^a ; ^{allison.j.brager.ctr@mail.mil} ; Lydia Heemstra^b ; Raman Bhambra^b ; J. Christopher Ehlen^c ; Karyn A. Esser^d ; Ketema N. Paul^e ; Colleen M. Novak^b
• 关键词：Insulin sensitivity ; Resting energy expenditure ; VO2 max ; Restricted sleep ; Treadmill running ; Molecular circadian clock
• 刊名：Biochimie
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：132
• 期：Complete
• 页码：161-165
• 全文大小：377 K
• 卷排序：132

文摘

Mice with overexpressed muscle clocks work harder on less fuel and recover quicker from exercise. Overexpressed mice are more sensitive to the positive metabolic effects of maximal exercise. Overexpressed mice are more sensitive to negative metabolic effects of acute sleep loss.