Regulation of hepatic cardiolipin metabolism by TNF伪: Implication in cancer cachexia
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- 作者：Laure Peytaa ; laure.peyta@etu.univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Kathleen Jarnouenb ; c ; kathleen.jarnouen@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author ; Michelle Pinaulta ; michelle.pinault@univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Cedric Coulouarnb ; c ; cedric.coulouarn@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author ; Cyrille Guimaraesa ; cyrille.guimaraes@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Caroline Goupillea ; d ; caroline.goupille@univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Jean-Paul Pais de Barrose ; jppais@u-bourgogne.fr" class="auth_mail" title="E-mail the corresponding author ; Stephan Chevaliera ; stephan.chevalier@univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Jean-Franç ; ois Dumasa ; jean-francois.dumas@univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Franç ; ois Maillota ; d ; maillot@med.univ-tours.fr" class="auth_mail" title="E-mail the corresponding author ; Grant M. Hatchf ; ghatch@chrim.ca" class="auth_mail" title="E-mail the corresponding author ; Pascal Loyerb ; c ; pascal.loyer@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author ; Stephane Servaisa ; stephane.servais@univ-tours.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：ALCAT1 ; acyl&ndash ; CoA ; lysocardiolipin acyltransferase ; CDP&ndash ; DAG ; diphosphate-1 ; 2-diacyl-sn-glycerol ; CDS ; cytidine-5&prime ; -diphosphate-1 ; 2-diacyl-sn-glycerol synthase ; CL ; cardiolipin ; CLS ; cardiolipin synthase ; DMSO ; dimethylsulfoxide ; ETS ; electron transfert system ; FCCP ; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; Hsc70 ; heat shock cognate 70 ; kDa ; iPLA2纬 ; calcium independent phospholipase A2 gamma ; MLCL AT-1 ; monolysocardi
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：1851
- 期：11
- 页码：1490-1500
- 全文大小：865 K
文摘
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First demonstration of liver cardiolipin metabolism alteration in cancer induced cachexia
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Direct implication of TNF伪 in mitochondrial energy wasting via cardiolipin modulation
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Increasing knowledge on cellular mechanism of liver energetic alteration during cancer cachexia