The interleukin-1β-511 T > C (rs16944) gene polymorphism is associated with risk of developing silent myocardial ischemia in diabetic patients
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- 作者：Gilberto Vargas-Alarcó ; na ; Miguel Cruz-Ló ; pezb ; Adá ; n Valladaresb ; Edith Á ; lvarez-Leó ; na ; Teresa Juá ; rez-Cedilloc ; Ó ; scar Pé ; rez-Mé ; ndeza ; Jorge Escobedo de-la-Peñ ; ad ; Galileo Escobedoe ; Jose Manuel Fragosoa ; mfragoso1275@yahoo.com.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：SMI ; Silent myocardial infarction ; IL-1β ; Interleukin-1 beta ; IL-1F10 ; Interleukin-1 family member 10 ; IL-1ra ; IL-1 receptor antagonist ; SNP ; Single nucleotide polymorphism ; MAF ; proto-oncogene c-MAF transcription factor
- 刊名：Immunology Letters
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：168
- 期：1
- 页码：7-12
- 全文大小：555 K
文摘
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The rs16944 polymorphism is associated with risk of developing SMI in diabetic patients.
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Under four inheritance models the CC and CT genotypes of the rs16944 SNP increased risk of developing SMI.
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The haplotypes CTCC, CCTC, CCCT and CTCC increased risk of developing SMI in diabetic patients.