Matching at Human Leukocyte Antigen-C Improved the Outcomes after Double Umbilical Cord Blood Transplantation for Recipients of Two to Four of Six Human Leukocyte Antigen-Matched Grafts

详细信息    查看全文

• 作者：Claudio G. Brunstein¹ ; ^{bruns072@umn.edu} ; Corey S. Cutler² ; Todd E. DeFor¹ ; Haesook Kim² ; Nelli Bejanyan¹ ; Alfred Garfall³ ; Michael R. Verneris¹ ; Yi-Bin Chen⁴ ; Erica D. Warlick¹ ; Thomas Spitzer⁴ ; Jeffrey S. Miller¹ ; Joseph H. Antin² ; Daniel J. Weisdorf¹ ; Robert Soiffer² ; John E. Wagner¹ ; Karen K. Ballen⁴
• 关键词：Alternative donor transplantation ; Human leukocyte antigen ; Double umbilical cord blood
• 刊名：Biology of Blood and Marrow Transplantation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：23
• 期：1
• 页码：126-133
• 全文大小：430 K
• 卷排序：23

文摘

In patients receiving 2–4/6 HLA matched UCB unit, additional matching at HLA-C reduces mortality and improves survival. In patients receiving 5–6/6 HLA matched UCB units, further matching at HLA-C offers no additional benefit.