The adult zebrafish retina: In vivo optical sectioning with Confocal Scanning Laser Ophthalmoscopy and Spectral-Domain Optical Coherence Tomography
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- 作者：Brent A. Bella ; bellb3@ccf.org" class="auth_mail" title="E-mail the corresponding author ; Alex Yuana ; b ; Rose M. Diciccoa ; Joseph Fogertya ; Emma M. Lessieura ; c ; Brian D. Perkinsa ; b
- 关键词：Zebrafish ; Retina ; SLO ; SDOCT ; Optical sectioning ; Morphology ; In vivo
- 刊名：Experimental Eye Research
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：153
- 期：Complete
- 页码：65-78
- 全文大小：4118 K
文摘
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A model is proposed explaining the outer retina banding pattern seen in zebrafish with high resolution SDOCT.
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By combining SLO and SDOCT imaging data, we demonstrate the ability to optically section through the retina.
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We demonstrate the influence of axial length and ocular power on SLO axial and transverse resolution and depth of field.
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We demonstrate the ability to resolve and catalog retinal features and/or abnormalities within multiple transgenic lines.