Direct CC coupling of phthalazine-N-oxide with the carboranyl anion - An original approach to C-modification of carboranes

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• 作者：Mikhail V. Varaksin^a ; ^b ; Lidiia A. Galliamova^a ; Olga A. Stepanova^a ; Oleg S. Eltsov^a ; Oleg N. Chupakhin^a ; ^b ; ^{chupakhin@ios.uran.ru} ; Valery N. Charushin^a ; ^b
• 关键词：Carboranes ; Phthalazine-N-oxide ; CC coupling
• 刊名：Journal of Organometallic Chemistry
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：830
• 期：Complete
• 页码：93-99
• 全文大小：967 K
• 卷排序：830

文摘

An original transition metal-free approach based on the direct CC coupling of phtalazine-N-oxide with the carboranyl anion has been developed. A series of the novel C-modified closo-carboranes such as 1-(2-oxido-3-acyl-3,4-dihydrophtalazinyl-4-yl)-1,2-dicarba-closo-dodecaboranes and 1-(2-formylbenzyl)-1,2-dicarba-closo-dodecaborane have been obtained. The synthesized boron clusters could be of interest as promising building blocks in design of BNCT delivery agents.