Impact of telomere length on survival in classic and variant hairy cell leukemia
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- 作者：Evgeny Aronsa ; Hong Zhoua ; Daniel C. Edelmanb ; Allison Gomezb ; Seth M. Steinbergc ; David Petersenb ; Yonghong Wangb ; Paul S. Meltzerb ; Robert J. Kreitmana ; kreitmar@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Telomere ; Hairy cell leukemia ; Molecular marker ; Chromosomes ; DNA damage
- 刊名：Leukemia Research
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：39
- 期：12
- 页码：1360-1366
- 全文大小：342 K
文摘
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Telomeres protect the ends of chromosomes but are sometimes shortened in leukemias.
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Short telomeres in hairy cell leukemia are associated with decreased overall survival.
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Short telomere length correlates with other poor prognosis factors in hairy cell leukemia.
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Low telomere length should be studied further in this disease.