Antagonistic sepsis markers: Serum gelsolin and actin/gelsolin ratio

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• 作者：Zolt&aacute ; n Horv&aacute ; th-Szalai ; MD^a ; ^d ; Pé ; ter Kust&aacute ; n ; MD^a ; ^b ; Di&aacute ; na Mü ; hl ; MD ; PhD^b ; Andrea Lud&aacute ; ny ; MD ; PhD^a ; ^d ; Be&aacute ; ta Bugyi ; PhD^c ; ^d ; Tam&aacute ; s Kőszegi ; MD ; PhD^a ; ^d ; ^{tamas.koszegi@aok.pte.hu} ; ^{koszegitam@gmail.com}
• 关键词：A ; actin ; GSN ; gelsolin ; A/GSN ; actin/gelsolin ; APACHE II ; Acute Physiology and Chronic Health Evaluation II ; MODS ; multiple organ dysfunction syndrome ; SAPS II ; Simplified Acute Physiology Score II ; SOFA ; Sequential Organ Failure Assessment
• 刊名：Clinical Biochemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：50
• 期：3
• 页码：127-133
• 全文大小：698 K
• 卷排序：50

文摘

Actin-scavenger gelsolin levels help in discriminating between SIRS and sepsis. Non-survivors have significantly decreased gelsolin levels compared to survivors. Gelsolin has similar prognostic value to procalcitonin based on 7-day mortality. First-day actin/gelsolin ratio has similar predictive value as APACHE II score.