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在“Elsevier”中，命中：707条，耗时：0.0750008 秒

1.Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists

作者：Sanjita Sasmal^a ; Gade Balaji^a ; Hariprasada R. Kanna Reddy^a ; D. Balasubrahmanyam^a ; Gujjary Srinivas^a ; ShivaKumar Kyasa^a ; Pradip K. Sasmal^a ; ^&dagger ; ; ^{pradipks@drreddys.com} ; ^{sasmalpk@yahoo.co.in} ; Ish Khanna^a ; Rashmi Talwar^a ; J. Suresh^a ; Vikram P. Jadhav^a ; Syed Muzeeb^a ; Dhanya Shashikumar^a ; K. Harinder Reddy^a ; V.J. Sebastian^a ; Thomas M. Frimurer^b ; Ø ; ystein Rist^b ; Lisbeth Elster^b ; Thomas Hö ; gberg^b ; ^&Dagger ;

关键词：Melanin concentrating hormone (MCH) ; MCHR1 antagonists ; MCH receptor ensembles ; Obesity

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

2.Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists: Part 2

作者：Sanjita Sasmal^a ; D. Balasubrahmanyam^a ; Hariprasada R. Kanna Reddy^a ; Gade Balaji^a ; Gujjary Srinivas^a ; Srisailam Cheera^a ; Chandrasekhar Abbineni^a ; Pradip K. Sasmal^a ; ^&dagger ; ; ^{pradipks@drreddys.com} ; ^{sasmalpk@yahoo.co.in} ; Ish Khanna^a ; V.J. Sebastian^a ; Vikram P. Jadhav^a ; Manvendra P. Singh^a ; Rashmi Talwar^a ; J. Suresh^a ; Dhanya Shashikumar^a ; K. Harinder Reddy^a ; V. Sihorkar^a ; Thomas M. Frimurer^b ; Ø ; ystein Rist^b ; Lisbeth Elster^b ; Thomas Hö ; gberg^b ; ^&Dagger ; ; ^{thomas.hogberg@leo-pharma.com}

关键词：Melanin concentrating hormone (MCH) ; Quinazolines ; MCHR1 antagonists ; hERG ; Obesity

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

3.Discovery of a novel melanin concentrating hormone receptor 1 (MCHR1) antagonist with reduced hERG inhibition

作者：Jeffrey T. Mihalic^a ; ^{jmihalic@amgen.com} ; Pingchen Fan^a ; Xiaoqi Chen^a ; Xi Chen^a ; Ying Fu^a ; Alykhan Motani^b ; Lingming Liang^b ; Michelle Lindstrom^b ; Liang Tang^c ; Jin-Long Chen^b ; Juan Jaen^a ; Kang Dai^b ; Leping Li^a

关键词：MCHR1 ; Melanin concentrating hormone ; Reducing hERG inhibition

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

4.An example of designed multiple ligands spanning protein classes: Dual MCH-1R antagonists/DPPIV inhibitors

作者：William T. Gattrell^a ; ^{wgattrell@yahoo.co.uk} ; Colin P. Sambrook Smith^a ; Alun J. Smith^b

关键词：Designed multiple ligands ; Type II diabetes ; MCH-1R ; DPPIV

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

5.Right atrial mass after open heart surgery: tumour or thrombus?

作者：Suresh Babu Kale ; MCh ; DNB ; ^{sureshbkale@gmail.com} ; Ashish Badkhal ; MCh ; Natarajan Meenakshinatan Kumar ; DNB ; Jagannathan Raghavan ; MCh

关键词：Atrium ; Paediatric ; Cardiac tumours ; Cardiopulmonary bypass

刊名：Heart ; Lung and Circulation

出版年：2012

6.From Theater to the World Wide Web鈥攁 New Online Era for Surgical Education

作者：D. Peter O'Leary ; MB ; MRCSI^鈦?/sup> ; ^{donaloleary@rcsi.ie} ; Mark A. Corrigan ; MD ; FRCSI^鈦?/sup> ; Seamus M. McHugh ; MD ; FRCSI^&dagger ; ; A.D. Hill ; MCh ; FRCSI^&dagger ; ; H. Paul Redmond ; MCh ; FRCSI^鈦?/sup>

关键词：surgery ; education ; e-learning

刊名：Journal of Surgical Education

出版年：2012

7.Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity

作者：Silvia Galiano ; Javier Ceras ; Nuria Cirauqui ; Silvia Pé ; rez ; Laura Juanenea ; Gildardo Rivera ; Ignacio Aldana ; Antonio Monge

关键词：MCH ; MCH-R1 antagonist ; Obesity ; Biphenylmethyl urea

刊名：Bioorganic and Medicinal Chemistry

出版年：2007

8.Health and nutritional status of Wistar rats following subchronic exposure to CV127 soybeans

作者：Amechi Chukwudebe^a ; ^{amechi.chukwudebe@basf.com} ; Laura Privalle^b ; Andrew Reed^b ; Christine Wandelt^c ; Daniela Contri^d ; Martina Dammann^e ; Sibylle Groeters^e ; Uwe Kaspers^e ; Volker Strauss^e ; Bennard van Ravenzwaay^e

关键词：WBC ; white blood cells/leukocytes ; RBC ; red blood cells/erythrocytes ; HGB ; hemoglobin ; HCT ; hematocrit ; MCV ; mean corpuscular volume ; MCH ; mean corpuscular hemoglobin ; MCHC ; mean corpuscular hemoglobin concentration ; PLT ; platelets ; RETI ; reticulocytes ; N

刊名：Food and Chemical Toxicology

出版年：2012

9.Reticulocyte hemoglobin content allows early and reliable detection of functional iron deficiency in blood donors

作者：M.J. Semmelrock^a ; ^e ; R.B. Raggam^b ; K. Amrein^c ; A. Avian^d ; K. Schallmoser^a ; G. Lanzer^a ; H.J. Semmelrock^b ; F. Prueller^b ; A. Berghold^d ; E. Rohde^f ; ^{e.rohde@salk.at}

关键词：IDA ; iron deficiency anemia ; Hb ; hemoglobin ; MCV ; mean corpuscular volume ; MCH ; mean corpuscular hemoglobin ; MCHC ; mean corpuscular hemoglobin concentration ; sTfR ; soluble transferrin receptor ; AIS ; absent iron stores ; sTfR-F ; ferritin index ; RBC ; red blo

刊名：Clinica Chimica Acta

出版年：2012

10.Synthesis and structure–activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1)

作者：Martin W. Rowbottom ; Troy D. Vickers ; Junko Tamiya ; Mingzhu Zhang ; Brian Dyck ; Jonathan Grey ; David Schwarz ; Christopher E. Heise ; Michael Hedrick ; Jenny Wen ; et al.

关键词：MCH ; MCH-R1 ; MCH antagonists ; Melanin-concentrating hormone receptor-1 antagonists ; Spirohydantion ; CYP3A4 ; Obesity

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2007

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