自拟青城散剂在汶川地震灾区治疗儿童过敏性皮炎的临床观察
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摘要
目的观察自拟方青城散剂在四川汶川地震灾区儿童过敏性皮炎治疗中的疗效。方法将578例过敏性皮炎患儿随机分为治疗组368例,对照组210例。治疗组给予自拟青城散糊剂外用,对照组给予皮炎平乳膏外用,2次/d,1~2周为1个疗程。结果治疗组总有效率94.8%,对照组总有效率83.3%,2组比较有显著性差异(P<0.05)。2组患儿治疗前后瘙痒程度及皮疹面积评分比较均有显著性差异(P均<0.01),治疗组瘙痒程度及皮疹面积评分较对照组改善更明显(P<0.05)。结论自拟青城散剂在地震灾区儿童过敏性皮炎治疗中有很好的疗效。
Objective It is to observe the curative effect of self-made prescription Qingchengsan on sensitization dermatitis in children at earthquake distress area in Wenchuan of Sichuan.Methods 578 cases of sensitization dermatitis in children were randomly divided into treatment group in which there were 368 cases and control group in which there were 210 cases.Treatment group was treated with self-made prescription Qingchengsan for external application and control group was treated with Compound Dexamethasone Ointment for external application.The therapies in the two groups were both twice a day and the treatment courses were both one to two weeks.Results The total effective rate in treatment group was 94.8% and that in control group was 83.3%,and there was significant difference in the two groups(P<0.05).There was significant difference on the scores of itching degree and skin rash area in the two groups before and after treatment(both P<0.05).The improvement on the scores of itching degree and skin rash area in treatment group was more obvious than that in control group(P<0.05).Conclusion Selfmade prescription Qingchengsan has better curative effect on sensitization dermatitis in children at earthquake distress area.
Objective It is to observe the curative effect of self-made prescription Qingchengsan on sensitization dermatitis in children at earthquake distress area in Wenchuan of Sichuan.Methods 578 cases of sensitization dermatitis in children were randomly divided into treatment group in which there were 368 cases and control group in which there were 210 cases.Treatment group was treated with self-made prescription Qingchengsan for external application and control group was treated with Compound Dexamethasone Ointment for external application.The therapies in the two groups were both twice a day and the treatment courses were both one to two weeks.Results The total effective rate in treatment group was 94.8% and that in control group was 83.3%,and there was significant difference in the two groups(P<0.05).There was significant difference on the scores of itching degree and skin rash area in the two groups before and after treatment(both P<0.05).The improvement on the scores of itching degree and skin rash area in treatment group was more obvious than that in control group(P<0.05).Conclusion Selfmade prescription Qingchengsan has better curative effect on sensitization dermatitis in children at earthquake distress area.
引文
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[3]Schade RP,Van Ieperen-Van Dijk AG,Van Reijsen FC,et al.Dif-ferences in antigen-specific T-cell responses between infants withatopic dermatitis with and without cow’s milk allergy:relevance ofTH2 cytokines[J].J Allergy Clin Immunol,2000,106(6):1155-1162
[4]张源,李岚,陈健.儿童过敏性皮炎变应原分析[J].现代中西医结合杂志,2006,15(18):2493
[5]高俊.中西医结合治疗药物过敏性皮炎28例临床观察[J].云南中医中药杂志,2001,22(4):18
[6]任少杰.自拟湿疹汤治疗湿疹57例[J].天津中医药,2008,25(1):62
[2]国家中医药管理局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:175
[3]Schade RP,Van Ieperen-Van Dijk AG,Van Reijsen FC,et al.Dif-ferences in antigen-specific T-cell responses between infants withatopic dermatitis with and without cow’s milk allergy:relevance ofTH2 cytokines[J].J Allergy Clin Immunol,2000,106(6):1155-1162
[4]张源,李岚,陈健.儿童过敏性皮炎变应原分析[J].现代中西医结合杂志,2006,15(18):2493
[5]高俊.中西医结合治疗药物过敏性皮炎28例临床观察[J].云南中医中药杂志,2001,22(4):18
[6]任少杰.自拟湿疹汤治疗湿疹57例[J].天津中医药,2008,25(1):62
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