地震挤压伤患者部分生化指标特征性改变分析
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摘要
目的探讨地震挤压伤患者(CIP)部分生化指标的变化特征,为灾难医学研究提供科学数据。方法对5.12大地震中本院收治的来自北川地震挤压伤患者230例(男120例、女110例)和健康对照组(当地未受伤群众)205例(男105例、女100例)进行肝肾功能、心肌酶谱、电解质等共19项生化指标测定。结果地震挤压伤患者组血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、尿素氮(BUN)、肌酐(CREA)、尿酸(UA)、肌酸激酶(CK)、肌酸激酶同功酶(CK-MB)、乳酸脱氢酶(LDH)、钾(K+)、镁(Mg2+)均高于健康对照组(P<0.05和P<0.01);地震挤压伤患者组血清总蛋白(TP)、白蛋白(ALB)、钠(Na+)、氯(Cl-)、钙(Ca2+)均低于健康对照组(P<0.05和P<0.01);地震挤压伤患者组血清谷氨酰转肽酶(GGT)、碱性磷酸酶(ALP)、总胆红素(T-BIL)、直接胆红素(D-BIL)与健康对照组比较差异无统计学意义(P>0.05),两组内男女之间所有指标比较差异无统计学意义。结论地震挤压伤患者部分生化指标较健康对照有明显改变,应严密监视,采取积极有效的预防和治疗措施,以降低危险。
Objective To explore how does the biochemical index change in the patients with earthquake related crush injury,and for providing scientifical data for disaster medicine..Methods We tested 19 conventional biochemical indexes of 230(male 120,female 110)patients with 5.12 earthquake related crush injury and 205(male 105,female 100)healthy people in BeiChuan.Results The serum ALT level of patients was significantly higher than that of the healthy people,as well as the AST、BUN、CREA、UA、CK、CK-MB、LDH、K+、Mg2+ levels(P<0.05 and P<0.01);The serum TP、ALB 、Na+、Cl-and Ca2+ levels are lower than the healthy people′s(P<0.05 and P<0.01)while there was no significant difference in the rest biochemical indexes between groups and in all indexes between sex(P>0.05).Conclusion Patients with earthquake related crush injury have an abnormal levels of biochemical indexes,Monitoring them should play an important role in clinical treatment guiding.
Objective To explore how does the biochemical index change in the patients with earthquake related crush injury,and for providing scientifical data for disaster medicine..Methods We tested 19 conventional biochemical indexes of 230(male 120,female 110)patients with 5.12 earthquake related crush injury and 205(male 105,female 100)healthy people in BeiChuan.Results The serum ALT level of patients was significantly higher than that of the healthy people,as well as the AST、BUN、CREA、UA、CK、CK-MB、LDH、K+、Mg2+ levels(P<0.05 and P<0.01);The serum TP、ALB 、Na+、Cl-and Ca2+ levels are lower than the healthy people′s(P<0.05 and P<0.01)while there was no significant difference in the rest biochemical indexes between groups and in all indexes between sex(P>0.05).Conclusion Patients with earthquake related crush injury have an abnormal levels of biochemical indexes,Monitoring them should play an important role in clinical treatment guiding.
引文
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[3]李广然.挤压伤致急性肾衰竭的治疗[J].新医学,2008,39(11):708-709.
[4]黄显凯.创伤后肝微循环障碍[J].战创伤参考资料,1996,25(4):28-31.
[5]屈纪富.58例严重挤压伤临床诊治分析[J].创伤外科杂志,2009,11(2):140-143.
[6]Abassi Z,Hoff man A,Beller O,et al.Acule renal failurecomplicating,muscle crush injury[J].Sermin Nephrol,2005,14(1):89.
[7]冶玉虎.重型颅脑损伤低钠血症患者48例临床分析[J].山东医药,2009,49(48):102-103.
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