地震灾区甲肝疫苗群体应急接种后免疫效果分析
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摘要
目的分析普种甲肝疫苗的县和未进行普种的县目标人群中HAV-IgG阳性率及两县甲肝疫情,评价甲肝疫苗免疫效果。方法对免疫效果监测结果及疾病监测信息系统资料进行分析。结果普种县监测对象HAV-IgG抗体阳性率为73.43%,未普种县监测对象HAV-IgG抗体阳性率为34.00%,两地区的差异有统计学意义(P﹤0.001);普种县和未普种县不同性别、不同年龄监测对象抗体阳性率差异无统计学意义(P﹥0.05)。普种县甲肝疫情下降趋势非常明显,普种后2年无15岁以下儿童甲肝发病报告。结论群体性应急接种甲肝疫苗,能有效预防相关传染病的发生,对目标人群甲肝疫情的控制效果显著。
OBJECTIVE To analyze the positive conversion rate of HAV-IgG between the county which has done the universal immunization of aimmugen and the county which has done the routine immunization,to compare the incidence of hepatitis A in two counties,and to estimate the effective after the immunization.METHODS Data from the results of immunity effect surveillance and the public health surveillance system were analyzed.RESULTS The positive conversion rate of HAV-IgG in the county which has done the universal immunization is 73.43%,the rate of another county is 34.00%,and the difference has statistical significance(P﹤0.001).The differences of sex and age have no statistical significance(P﹥0.05).The decreasing tendency of the incidence of HAV in the county which has done the universal immunization is significant.Two years after the universal immunization,we received no report about HAV of children who were less than fifteen years old.CONCLUSION The emergency immunization of group nature has significant effect for preventing occurrence of related disease and controlling the incidence of HAV in the objective group.
OBJECTIVE To analyze the positive conversion rate of HAV-IgG between the county which has done the universal immunization of aimmugen and the county which has done the routine immunization,to compare the incidence of hepatitis A in two counties,and to estimate the effective after the immunization.METHODS Data from the results of immunity effect surveillance and the public health surveillance system were analyzed.RESULTS The positive conversion rate of HAV-IgG in the county which has done the universal immunization is 73.43%,the rate of another county is 34.00%,and the difference has statistical significance(P﹤0.001).The differences of sex and age have no statistical significance(P﹥0.05).The decreasing tendency of the incidence of HAV in the county which has done the universal immunization is significant.Two years after the universal immunization,we received no report about HAV of children who were less than fifteen years old.CONCLUSION The emergency immunization of group nature has significant effect for preventing occurrence of related disease and controlling the incidence of HAV in the objective group.
引文
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[2]杨明强,马占钦,李园园,等.保山市甲肝疫苗大规模免疫接种免疫效果评价[J].中国公共卫生,2008,24(3):366.
[3]王冬梅.多种甲肝疫苗的免疫效果评价[J].海南医学,2009,20(2):106-107.
[4]陈永权,陈浩,贾谊军,等.甲肝减毒活疫苗免疫效果血清学调查[J].浙江预防医学,2008,20(5):22,23.
[5]许国章,陈耀荣,姜立民,等.冻干甲肝减毒活疫苗免疫原性及持久性分析[J].中国公共卫生,2008,24(11):1407-1408.
[6]孙家明,李明珠,杨晓婧,等.国产甲肝减毒活疫苗免疫效果监测[J].预防医学文献信息,1998,4(2):146.
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