976例汶川地震极重灾区再生育妇女助孕结果分析
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摘要
目的总结汶川地震灾区4年来再生育服务工作和助孕结果,对妇女的妊娠、流产及其他相关因素进行分析,探讨地震灾害、年龄及其他因素对再生育妇女妊娠及妊娠结局的影响。方法选取2008年5月至2012年5月,有再生育意愿妇女976例为研究对象,将其按年龄分为<35岁组(n=340)、35～39岁组(n=295)和≥40岁组(n=341)。采取回顾性分析法对其妊娠、妊娠结局及其他影响因素进行分析。结果 976例再生育妇女中,800例妊娠,妊娠率为81.97%(800/976),妊娠率随年龄增大而降低;妊娠自然流产率为20.25%(162/800),流产率随妊娠妇女年龄增大而增高;孕期确诊缺陷儿及时终止妊娠7例,有效干预了缺陷儿的出生。结论四川汶川地震极重灾区再生育妇女,由于各种综合因素影响,妊娠率随年龄增大而降低,妊娠自然流产率(20.25%)明显高于育龄期女性自然流产发生率(10%～15%),而及时、有效的综合预防和干预,是提高其妊娠率、降低流产率、减少缺陷儿出生的必要措施。
Objective:To analyze the results including pregnancy and abortion rate of assisted re-fertility in the earthquake-devastated area of Wenchuan County in Sichuan Province,and explore the influence of the earthquake,age and other related factors on the pregnancy outcome. Methods:From May 2008 to May 2012,976 women who wished re-fertility were included in this study and divided into three groups by their age:<35 years old(n = 340),35-39 years old(n= 295) and≥40 years old(?7 = 341).Their pregnancy outcome and other influencing factor were analyzed retrospectively. Results:Among these 976 women,800 patients successfully got pregnancy.The pregnant rate was 81.97%(800/976),and the abortion rate was 20.25%(162/800).The lower pregnant rate and the higher abortion rate were associated with elder age.Seven patients were terminated the pregnancy due to the fetus suffered congenital malformation.This effective intervention avoids the birth of the fetus with congenital malformation. Conclusions:The spontaneous abortion rate(20.25%) of the re-fertility women in the earthquake area is obviously higher than normal(10%-15%).Because of the comprehensive factors,the lower pregnant rate and the higher abortion rate were associated with elder age.The immediate and effective comprehensive measures of prevention and intervention were necessary to improve the pregnancy rate, decline the abortion rate and prevent the birth of the fetus with congenital malformation.
Objective:To analyze the results including pregnancy and abortion rate of assisted re-fertility in the earthquake-devastated area of Wenchuan County in Sichuan Province,and explore the influence of the earthquake,age and other related factors on the pregnancy outcome. Methods:From May 2008 to May 2012,976 women who wished re-fertility were included in this study and divided into three groups by their age:<35 years old(n = 340),35-39 years old(n= 295) and≥40 years old(?7 = 341).Their pregnancy outcome and other influencing factor were analyzed retrospectively. Results:Among these 976 women,800 patients successfully got pregnancy.The pregnant rate was 81.97%(800/976),and the abortion rate was 20.25%(162/800).The lower pregnant rate and the higher abortion rate were associated with elder age.Seven patients were terminated the pregnancy due to the fetus suffered congenital malformation.This effective intervention avoids the birth of the fetus with congenital malformation. Conclusions:The spontaneous abortion rate(20.25%) of the re-fertility women in the earthquake area is obviously higher than normal(10%-15%).Because of the comprehensive factors,the lower pregnant rate and the higher abortion rate were associated with elder age.The immediate and effective comprehensive measures of prevention and intervention were necessary to improve the pregnancy rate, decline the abortion rate and prevent the birth of the fetus with congenital malformation.
引文
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[2]冯文霄.国内外出生缺陷的流行分布情况[J].中国妇幼保健, 2012,27:1586-1589.
[3]甘汝红.出生缺陷儿531例分析[J].齐齐哈尔医学院学报, 2012,33:465-466.
[4]De Cherney AH主编.现代妇产科疾病诊断与治疗[M].第8版.北京:人民卫生出版社,1998:1018-1019.
[5]曹泽毅主编.中华妇产科学[M].第2版.北京:人民卫生出版社,2004:1101-1102.
[6]乐杰主编.妇产科学[M].第7版.北京:人民卫生出版社, 2008.82-86.
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