食品中磷脂提取及分析方法的研究进展
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摘要
磷脂是细胞的重要组成成分,对生物体的生长和发育具有重要作用,也是天然的乳化剂、表面活性剂,在食品、医药、化妆品等领域具有广泛的应用。由于每种磷脂分子可以结合不同的脂肪酸,导致磷脂种类繁多且结构复杂,对磷脂的分析比较困难。本文从磷脂的种类及应用、提取纯化、检测方法等方面,对食品中磷脂的研究进展进行概述,比较不同研究方法的优缺点,以期为不同食品中磷脂的深入研究和开发提供参考。
Phospholipids are the important components of cells and play an important role in the growth and development of organisms. They are also natural emulsifiers and surfactants, and have a wide range of applications in food, medicine, cosmetics and other fields. Each phospholipid molecule can bind to different fatty acids, which lead to a variety of phospholipids and complex structure, so the analysis of phospholipids is more difficult. This paper summarized the research progress of phospholipids in foods from the aspects of phospholipids, application,extraction, purification and detection methods, and compared the advantages and disadvantages of different research methods, in order to provide reference for the in-depth research and development of phospholipids in different foods.
Phospholipids are the important components of cells and play an important role in the growth and development of organisms. They are also natural emulsifiers and surfactants, and have a wide range of applications in food, medicine, cosmetics and other fields. Each phospholipid molecule can bind to different fatty acids, which lead to a variety of phospholipids and complex structure, so the analysis of phospholipids is more difficult. This paper summarized the research progress of phospholipids in foods from the aspects of phospholipids, application,extraction, purification and detection methods, and compared the advantages and disadvantages of different research methods, in order to provide reference for the in-depth research and development of phospholipids in different foods.
引文
[1]毕爽,李杨,毛惠婷,等.超声波处理蛋白质-磷脂复合物结构与功能性构效关系解析[J].食品与发酵工业,2016,42(10):61-67.Bi S,Li Y,Mao HT,et al.Analysis of structure and functional structure-activity relationship of ultrasonic treatment of protein-phospholipid complex[J].Food Ferm Ind,2016,42(10):61-67.
[2]李硕绵,李妹玲,乔宁,等.β-CD去除蛋黄卵磷脂中胆固醇工艺的研究[J].黑龙江畜牧兽医,2015,(6):137-139.Li SM,Li ML,Qiao N,et al.Study on the removal of cholesterol from egg yolk lecithin byβ-CD[J].Heilongjiang Anim Husband Veter,2015,(6):137-139.
[3]李桂华,王成涛.大豆磷脂中糖脂含量的测定[J].河南工业大学学报(自然科学版),2010,(4):5-8.Li GH,Wang CT.Determination of glycolipid content in soybean phospholipids[J].J Henan Univ Technol(Nat Sci Ed),2010,(4):5-8.
[4]王兆明,贺稚非,余力,等.动物源卵磷脂功效作用及其分析方法[J].食品工业科技,2014,35(19):362-367.Wang ZM,He ZF,Yu L,et al.Effect of animal source lecithin and its analytical method[J].Sci Technol Food Ind,2014,35(19):362-367.
[5]孟思,肇立春,王佳佳,等.大豆磷脂酰胆碱提取工艺优化[J].农业工程,2016,(3):52-53.Meng S,Zhao LC,Wang JJ,et al.Optimization of extraction process of soybean phosphatidylcholine[J].Agric Eng,2016,(3):52-53.
[6]梁丽,常明,刘睿杰,等.磷脂酶研究进展[J].食品工业科技,2013,(4):393-396.Liang L,Chang M,Liu RJ,et al.Progress in phospholipase research[J].Sci Technol Food Ind,2013,(4):393-396.
[7]Kenler ASMD,Swails WSRD,Driscoll DFPD,et al.Early enteral feeding in postsurgical cancer patients:fish oil structured lipid-based polymeric formula versus a standard polymeric formula[J].Ann Surg,1996,223(3):316-333.
[8]赵雪,高峰,辛建丽.多烯磷脂酰胆碱对异氟烷所致肝损害患者肝功能的影响[J].中国药业,2017,(11):50-52.Zhao X,Gao F,Xin JL.Effects of polyene phosphatidylcholine on liver function in patients with liver injury induced by isoflurane[J].Chin Pharm Ind,2017,(11):50-52.
[9]里慧,付佳奇,俞微微,等.鱼脑磷脂对小鼠脂质代谢的影响[J].食品与机械,2015,31(2):203-204.Li H,Fu JQ,Yu WW,et al.Effects of fish brain phospholipids on lipid metabolism in mice[J].Food Mach,2015,31(2):203-204.
[10]Chung SY,Moriyama T,Uezu E,et al.Administration of phosphatidylcholine increases brain acetylcholine concentration and improves memory in mice with dementia[J].J Nutr,1995,125(6):1484-1489.
[11]McClements DJ,Gumus CE.Natural emulsifiers-Biosurfactants,phospholipids,biopolymers,and colloidal particles:Molecular and physicochemical basis of functional performance[J].Adv Colloid Interf Sci,2016,(234):3-26.
[12]Oke M,Jacob JK,Paliyath G.Effect of soy lecithin in enhancing fruit juice/sauce quality[J].Food Res Int,2010,43(1):232-240.
[13]Kasinos M,Tran LT,Vander MP.Improved heat stability of recombined evaporated milk emulsions upon addition of phospholipid enriched dairy by-products[J].Food Hyd,2014,(34):112-118.
[14]胡玲玲,顾莞婷,谭六艳,等.粉末磷脂对保育仔猪生长性能的影响[J].饲料与畜牧,2017,(2):3 5-37.Hu LL,Gu WT,Tan LY,et al.Effect of powdered phospholipids on growth performance of nursery piglets[J].Feed Livestock,2017,(2):35-37.
[15]张艳艳,李珂,王晓晓,等.磷脂对中华绒鳌蟹幼蟹生长和饲料利用的影响[J].饲料工业,2013,(16):52-54.Zhang YY,Li K,Wang XX,et al.Effects of phospholipids on growth and feed utilization of juvenile crab[J].Feed Ind,2013,(16):52-54.
[16]杨志欣,程静,张文君,等.苦参总黄酮磷脂复合物的制备及优化[J].中药新药与临床药理,2018,(3):342-346.Yang ZX,Cheng J,Zhang WJ,et al.Preparation and characterization of total flavonoids phospholipid complex from sophora flavenscens[J].Trad Chin Drug Res Clin Pharm,2018,(3):342-346.
[17]关润伶,邹静,朱红.大豆卵磷脂的分离纯化研究进展[J].中国食品添加剂,2005,(5):44-47,59.Guan RL,Zhou J,Zhu H.Advance in separation and purification technology of soybean lecithin[J].Chin Food Add,2005,(5):44-47,59.
[18]陈玉江,殷涌光,李扬,等.高压脉冲电场作用于蛋黄卵磷脂提取过程的研究[J].食品科学,2006,(12):781-784.Chen YJ,Yin YG,Li Y,et al.Study on the effect of high pulsed electric fields on the process of extracting egg yolk lecithin[J].Food Sci,2006,(12):781-784.
[19]韩伟,吕金懋,陈惠丹,等.从蛋黄中提取卵磷脂的微波辅助萃取新工艺[J].机电信息,2009,(5):45-48.Han L,Lv JM,Chen HD,et al.Microwave-assisted extraction of lecithin from egg yolk[J].Electr Inform,2009,(5):45-48.
[20]彭述辉,黄利华,熊波,等.大豆卵磷脂分离纯化工艺的研究进展[J].大豆科技,2012,(4):29-32.Peng SH,Huang LH,Xiong B,et al.Advances in extraction and purification of soy lecithin[J].Soybean Technol,2012,(4):29-32.
[21]王二雷,宫新统,刘静波.蛋黄卵磷脂研究概况[J].食品工业科技,2010,(5):414-416,420.Wang EL,Gong XT,Liu JB,et al.Overview on study of egg yolk lecithin[J].Sci Technol Food Ind,2010,(5):414-416,420.
[22]刘颖,肖静静,李硕绵,等.蛋黄卵磷脂提取方法的研究[J].河北农业大学学报,2013,36(6):105-108.Liu Y,Xiao JJ,Li SM,et al.Study on the extraction methods of egg yolk lecithin[J].J Agric Univ Hebei,2013,36(6):105-108.
[23]Shah A,Akoh CC,Toledo RT,et al.Isolation of a phospholipid fraction from inedible egg[J].J Supercrit Fluid,2004,30(3):303-313.
[24]Gigliotti JC,Davenport MP,Beamer SK,et al.Extraction and characterisation of lipids from Antarctic krill(Euphausia superba)[J].Food Chem,2011,125(3):1028-1036.
[25]宋晓燕,周锦珂,李金华,等.超声强化提取蛋黄卵磷脂的工艺研究[J].中药材,2008,31(10):1572-1574.Song XY,Zhou JK,Li JH,et al.Study on ultrasonic enhanced extraction of egg yolk lecithin[J].Chin Herb Med,2008,31(10):1572-1574.
[26]黄群,麻成金,马美湖,等.超声波辅助提取鹌鹑蛋黄卵磷脂研究[J].食品科学,2006,27(11):297-300.Huang Q,Ma CJ,Ma MH,et al.Study on extraction of lecithin from quail's egg yolk with ultrasonic[J].Food Sci,2006,27(11):297-300.
[27]范劲松,李斌,徐保立,等.超临界CO2对蛋黄卵磷脂提取影响因素的探讨[J].粮油加工,2010,(5):103-106.Fan JS,Li B,Xu BL,et al.Discussion on the factors affecting the extraction of lecithin from egg yolk by supercritical CO2[J].Cere Oil Prod,2010,(5):103-106.
[28]刘博,陈开勋,陈渭萍,等.肉豆蔻超临界二氧化碳萃取工艺及其精油的GC-MS分析研究[J].香料香精化妆品,2003,(4):17-19.Liu B,Chen KX,Chen WP,et al.Study on extraction of nutmeg by supercritical carbon dioxide and GC-MS analytical[J].Flav Fragr Cosmet,2003,(4):17-19.
[29]林影影,阳向波,纪奇森,等.超临界CO2与乙醇结合工艺制备蛋黄油及其质量控制[J].亚太传统医药,2016,(23):28-31.Lin YY,Yang XB,Ji QS,et al.Preparation of egg yolk oil by supercritical CO2 and ethanol combined process and its quality control[J].Asia-Pacific Trad Med,2016,(23):28-31.
[30]张民,胡云翔,孙学文,等.超(亚)临界丙烷萃取蛋黄卵磷脂-由实验室走向工业化[J].食品工业科技,2016,(1):152-154,157.Zhang M,Hu YX,Sun XW,et al.Supercritical(subcritical)extraction of egg yolk lecithinwith propane-from lab scale to industry pilot[J].Sci Technol Food Ind,2016,(1):152-154,157.
[31]曾虹燕,方芳,蒋丽娟.超临界CO2萃取大豆油与大豆磷脂工艺条件研究[J].生物技术,2003,13(2):37-39.Ceng HY,Fang F,Jiang LJ.Studies on the technology of extracting soybean oil and phospholipid with supercritical CO2[J].Biotechnology,2003,13(2):37-39.
[32]夏杨毅,李洪军,鲁言文,等.超临界CO2高效萃取卵黄磷脂的研究[J].粮油加工与食品机械,2004,(8):46-47,50.Xia YY,Li HJ,Lu YW,et al.Study on efficient extraction of egg yolk lecithin with superoritical CO2[J].Grain Oil Process Food Mach,2004,(8):46-47,50.
[33]Teberikler L,Koseoglu S,Akgerman A.Selective extraction of phosphatidylcholine from lecithin by supercritical carbon dioxide/ethanol mixture[J].J Am Oil Chem Soc,2001,78(2):115-120.
[34]王秀嫔,李培武,张文,等.超声提取正相高效液相色谱法测定大豆及大豆油中的磷酸甘油酯[J].分析测试学报,2011,(5):527-531.Wang XP,Li PW,Zhang W,et al.Detection of phospholipid compounds in soybean and soybean oil samples using ultrasonic extraction and normal-phase HPLC with UV detection[J].J Instrum Anal,2011,(5):527-531.
[35]曲怀坤.蛋黄卵磷脂的提取方法研究[J].山东食品发酵,2011,(3):18-21.Qu HK.The study on extraction of egg yolk lecithin[J].Shandong Food Ferment,2011,(3):18-21.
[36]王磊,高正松,万辉,等.氧化铝吸附提纯大豆卵磷脂的工艺研究[J].食品工业科技,2013,(6):296-298.Wang L,Gao ZS,Wan H,et al.Purification process of soyabean lecithin by alumina adsorption method[J].Sci Technol Food Ind,2013,(6):296-298.
[37]Hoi DU,Lo S.Separation of phospholipids using a diethylaminoethyl-silica gel column and thin-layer chromatography[J].JChromatogr B,1986,(381):233-240.
[38]徐晨.大豆卵磷脂的提纯研究[J].天然产物研究与开发,1998,(2):75-78.Xu C.Research of soybean lecithin extraction[J].Nat Prod Res Dev,1998,(2):75-78.
[39]吴汉东,佟伟.高纯度蛋黄卵磷脂的提取工艺研究[J].安徽农业科学,2010,38(14):7537-7538.Wu HD,Tong W.Study on the extraction technology of high-purity egg yolk lecithin[J].J Anhui Agric Sci,2010,38(14):7537-7538.
[40]Barry KM,Dinan TG,Kelly PM.Pilot scale production of a phospholipid-enriched dairy ingredient by means of an optimised integrated process employing enzymatic hydrolysis,ultrafiltration and super-critical fluid extraction[J].Innov Food Sci Emerg Technol,2017,(41):301-306.
[41]徐晓斌,李俊玲,杨阳,等.南极磷虾油酶解法提取工艺研究[J].中国油脂,2015,(5):5-8.Xu XB,Li JL,Yang Y,et al.Enzymatic extraction of Antarctic krill oil[J].China Oil Fat,2015,(5):5-8.
[42]赵彦巧,李建颖,吴子健,等.酶解超声辅助卵磷脂的提取工艺[J].食品研究与开发,2012,(11):93-96.Zhao YQ,Li JY,Wu ZJ,et al.Enzymolysis ultrasonic-assisted extraction of lecithin from egg yolk powder[J].Food Res Dev,2012,(11):93-96.
[43]李才明,许学勤,王卫芬,等.鲜鸡蛋蛋黄酶法提油工艺的研究[J].食品与发酵工业,2008,(8):83-85.Li CM,Xu XQ,Wang WF,et al.The technology of the enzymatic extraction oil from fresh egg yolk[J].Food Ferm Ind,2008,(8):83-85.
[44]Navidghasemizad S,Temelli F,Wu J.Moisture impact on extractability of phospholipids from leftover egg yolk after enzymatic treatment using supercritical carbon dioxide[J].Food Bioprod Process,2015,(94):473-481.
[45]Konrad G,Kleinschmidt T,Lorenz C.Ultrafiltration of whey buttermilk to obtain a phospholipid concentrate[J].Inter Dair J,2013,30(1):39-44.
[46]Barry KM,Dinan TG,Kelly PM.Selective enrichment of dairy phospholipids in a buttermilk substrate through investigation of enzymatic hydrolysis of milk proteins in conjunction with ultrafiltration[J].Int Dair J,2017,(68):80-87.
[47]郭勍,徐桂云,常理文.大豆磷脂组成的薄层色谱分析[J].分析化学,1998,(1):81-84.Guo Q,Xu GY,Chang LW.Analysis of soybean phospholipids by thin-layer chromatography[J].Chin J Anal Chem,1998,(1):81-84.
[48]马辰,段宏瑾.大豆磷脂中磷脂类成分的含量测定[J].中国中药杂志,1999,(11):31-32.Ma C,Duan HJ.Determination of phospholipids in soybean phospholipids[J].China J Chin Mater Med,1999,(11):31-32.
[49]张卓勇,罗茜,郭黎平.吉林大豆中卵磷脂的成分提取与分析[J].东北师大学报(自然科学版),2001,(2):37-43.Zhang ZY,Luo Q,Guo LP.Extraction and analysis of lecithin components in soybeans in Jilin province[J].J Northeast Norm Univ(Nat Sci Ed),2001,(2):37-43.
[50]鲍风,张克,文德成.大豆磷脂组成的研究Ⅰ.磷脂组成的薄层色谱分析[J].生物化学与生物物理学报,1981,(4):373-378.Bao F,Zhang K,Wen DC.Studies on the composition of soybean phospholipids I.Thin layer chromatography analysis of phospholipid composition[J].J Biochem Biophys,1981,(4):373-378.
[51]Christie WW,Urwin RA.Separation of lipid classes from plant tissues by high performance liquid chromatography on chemically bonded stationary phases[J].J High Resolut Chromatogr,1995,18(2):97-100.
[52]Mawatari S,Okuma Y,Fujino T.Separation of intact plasmalogens and all other phospholipids by a single run of high-performance liquid chromatography[J].Anal Biochem,2007,370(1):54-59.
[53]李国辉,钟其顶,王道兵,等.HPLC法测定大豆磷脂及其保健品中PC、PI、PE[J].食品研究与开发,2015,(6):67-70.Li GH,Zhong QD,Wang DB,et al.Determination of the concentrations of phosphatidylcholine,phosphatidyl ethanolamine and phosphatidylinositol in soybean phospholipids and health care products by HPLC[J].Food Res Dev,2015,(6):67-70.
[54]Yamagishi T,Akiyama H,Kimura S,et al.Quantitative determination of phosphatidylcholine by an HPLC-RI system[J].J Am Oil Chem Soc,1989,66(12):1801-1808.
[55]Rhee JS,Shin MG.Analysis of phosphatidylcholine in soy lecithins by HPLC[J].J Am Oil Chem Soc,1982,59(2):98-99.
[56]Der Meeren PV,Vanderdeelen J,Huys M,et al.Simple and rapid method for high-performance liquid chromatographic separation and quantification of soybean phospholipids[J].J Chromatogr A,1988,447(S):436-442.
[57]刘静波,常皓,王二雷,等.高效液相色谱法检测蛋黄卵磷脂中的磷脂酰胆碱[J].吉林大学学报(工学版),2012(S1):449-453.Liu JB,Chang H,Wang EL,et al.Phosphatidylcholine of egg yolk lecithin detection using high performance liquid chromatography(HPLC)[J].J Jilin Univ(Eng Technol Ed),2012(S1):449-453.
[58]章慧芳,陆娅.大豆磷脂中卵磷脂检测方法的研究[J].中国油脂,2007,32(7):70-73.Zhang HF,Lu Y.Determination of soybean phosphatidylcholine[J].China Oil Fat,2007,32(7):70-73.
[59]Rodr??guez-Bernaldo DQA,López-Hernández J,Simal-Lozano J.Separation of phospholipid classes in sea urchin,Paracentrotus lividus by high-performance liquid chromatography[J].J Chromatogr B,2002,770(1):71-75.
[60]Hanson VL,Park JY,Osborn TW,et al.High-performance liquid chromatographic analysis of egg yolk phospholipids[J].J Chromatogr A,1981,205(2):393-400.
[61]曹栋.HPLC-ESLD法分离测定大豆磷脂酰胆碱[J].中国油脂,2005,30(12):43-45.Cao D.Separation and determination of soybean phosphatidylcholine in soybean phospholipid by HPLC-ELSD[J].China Oil Fat,2005,30(12):43-45.
[62]Balazs PE,Schmit PL,Szuhaj BF.High-performance liquid chromatographic separations of soy phospholipids[J].J Am Oil Chem Soc,1996,73(2):193-197.
[63]Mcnabb TJ,Cremest A.High-performance liqued chromatography evaporative light-scattering detector techniques for neutral,polar,and acidic lipid classes a review of methods and detector models[J].Semin Food Anal,1999,4(1):53-69.
[64]王琦,薛长湖,徐杰,等.HPLC-ELSD法测定几种水产品卵及生殖腺中磷脂的组成[J].分析仪器,2012,(5):18-22.Wang Q,Xue CH,Xu J,et al.Determination of phospholipids in egg/gonad from several aquatic products by HPLC-ELSD[J].Anal Instrum,2012,(5):18-22.
[65]朱瑶,陈慧民,卢航,等.刺参性腺中6种磷脂含量的HPLC-ELSD分析[J].大连海洋大学学报,2015,30(4):422-425.Zhu Y,Chen HM,Lu H,et al.HPLC-ELSD analysis of six phospholipids in the gland of sea cucumber[J].J Dalian Ocean Univ,2015,30(4):422-425.
[66]Zhang Y,Cn YYCZ,Ren Q,et al.Quantification of soybean phospholipids in soybean degummed oil residue by HPLC with evaporative light scattering detection[J].J Liq Chromatogr Relat Technol,2017,28(9):1333-1343.
[67]陈康,戴志远,沈清,等.响应面法提取南极磷虾磷脂及其分子种组成的测定[J].南方水产科学,2017,13(3):104-112.Chen K,Dai ZY,Shen Q,et al.Extraction of phospholipid from Euphausia superba by response surface method and determination of phospholipid molecular species[J].South China Fish Sci,2017,13(3):104-112.
[68]Ali AH,Zou X,Huang J,et al.Profiling of phospholipids molecular species from different mammalian milk powders by using ultra-performance liquid chromatography-electrospray ionization-quadrupole-time of flight-mass spectrometry[J].J Food Compos Anal,2017,(1):143-154.
[69]Liang P,Li R,Sun H,et al.Phospholipids composition and molecular species of large yellow croaker(Pseudosciaena crocea)roe[J].Food Chem,2018,(245):806-811.
[70]周瑢,黏慧青,陈华勇,等.磷脂检测新技术[J].现代科学仪器,2008,(1):61-64.Zhou Rian HQ,Chen HR,et al.Phospholipids analysis by new technology[J].Mod Sci Instrum,2008,(1):61-64.
[71]刘纯友,马美湖,王庆玲,等.核磁共振技术在食品脂质研究中的应用新进展[J].食品工业科技,2017,38(12):342-346.Liu CY,Ma MH,Wang QL,et al.New advances of application of nuclear magnetic resonance technology in food lipid research[J].Sci Technol Food Ind,2017,38(12):342-346.
[72]庞思勉,张明霞,姬红萍.31P核磁共振光谱法测定坚果类食品中的6种磷脂[J].理化检验-化学分册,2016,52(1):44-46,47.Pang SM,Zhang MX,Ji HP.Determination of 6 phospholipids in nuts by31P-NMR[J].Phys Test Chem Anal B,2016,52(1):44-47.
[73]崔常乐,滕英来,汪勇,等.核磁共振磷谱内标法测定磷脂酰胆碱的含量[J].中国粮油学报,2016,31(5):158-162.Cui CL,Teng YL,Wang Y,et al.Quantitative determination of phosphatidylcholine by 31P nuclear magnetic resonance(31P-NMR)with internal standard method[J].J Chin Cereal Oil Assoc,2016,31(5):158-162.
[74]俞乐,丛芳,王兴国,等.不同来源大豆毛油磷脂组成的核磁检测及磷脂酸含量比较[J].中国油脂,2017,(1):130-133.Yu L,Cong F,Wang XG,et al.Determination of phospholipids composition in crude soybean oil from different sources by nuclear magnetic resonance and comparison of phosphatidic acid content[J].China Oil Fat,2017,(1):130-133.
[2]李硕绵,李妹玲,乔宁,等.β-CD去除蛋黄卵磷脂中胆固醇工艺的研究[J].黑龙江畜牧兽医,2015,(6):137-139.Li SM,Li ML,Qiao N,et al.Study on the removal of cholesterol from egg yolk lecithin byβ-CD[J].Heilongjiang Anim Husband Veter,2015,(6):137-139.
[3]李桂华,王成涛.大豆磷脂中糖脂含量的测定[J].河南工业大学学报(自然科学版),2010,(4):5-8.Li GH,Wang CT.Determination of glycolipid content in soybean phospholipids[J].J Henan Univ Technol(Nat Sci Ed),2010,(4):5-8.
[4]王兆明,贺稚非,余力,等.动物源卵磷脂功效作用及其分析方法[J].食品工业科技,2014,35(19):362-367.Wang ZM,He ZF,Yu L,et al.Effect of animal source lecithin and its analytical method[J].Sci Technol Food Ind,2014,35(19):362-367.
[5]孟思,肇立春,王佳佳,等.大豆磷脂酰胆碱提取工艺优化[J].农业工程,2016,(3):52-53.Meng S,Zhao LC,Wang JJ,et al.Optimization of extraction process of soybean phosphatidylcholine[J].Agric Eng,2016,(3):52-53.
[6]梁丽,常明,刘睿杰,等.磷脂酶研究进展[J].食品工业科技,2013,(4):393-396.Liang L,Chang M,Liu RJ,et al.Progress in phospholipase research[J].Sci Technol Food Ind,2013,(4):393-396.
[7]Kenler ASMD,Swails WSRD,Driscoll DFPD,et al.Early enteral feeding in postsurgical cancer patients:fish oil structured lipid-based polymeric formula versus a standard polymeric formula[J].Ann Surg,1996,223(3):316-333.
[8]赵雪,高峰,辛建丽.多烯磷脂酰胆碱对异氟烷所致肝损害患者肝功能的影响[J].中国药业,2017,(11):50-52.Zhao X,Gao F,Xin JL.Effects of polyene phosphatidylcholine on liver function in patients with liver injury induced by isoflurane[J].Chin Pharm Ind,2017,(11):50-52.
[9]里慧,付佳奇,俞微微,等.鱼脑磷脂对小鼠脂质代谢的影响[J].食品与机械,2015,31(2):203-204.Li H,Fu JQ,Yu WW,et al.Effects of fish brain phospholipids on lipid metabolism in mice[J].Food Mach,2015,31(2):203-204.
[10]Chung SY,Moriyama T,Uezu E,et al.Administration of phosphatidylcholine increases brain acetylcholine concentration and improves memory in mice with dementia[J].J Nutr,1995,125(6):1484-1489.
[11]McClements DJ,Gumus CE.Natural emulsifiers-Biosurfactants,phospholipids,biopolymers,and colloidal particles:Molecular and physicochemical basis of functional performance[J].Adv Colloid Interf Sci,2016,(234):3-26.
[12]Oke M,Jacob JK,Paliyath G.Effect of soy lecithin in enhancing fruit juice/sauce quality[J].Food Res Int,2010,43(1):232-240.
[13]Kasinos M,Tran LT,Vander MP.Improved heat stability of recombined evaporated milk emulsions upon addition of phospholipid enriched dairy by-products[J].Food Hyd,2014,(34):112-118.
[14]胡玲玲,顾莞婷,谭六艳,等.粉末磷脂对保育仔猪生长性能的影响[J].饲料与畜牧,2017,(2):3 5-37.Hu LL,Gu WT,Tan LY,et al.Effect of powdered phospholipids on growth performance of nursery piglets[J].Feed Livestock,2017,(2):35-37.
[15]张艳艳,李珂,王晓晓,等.磷脂对中华绒鳌蟹幼蟹生长和饲料利用的影响[J].饲料工业,2013,(16):52-54.Zhang YY,Li K,Wang XX,et al.Effects of phospholipids on growth and feed utilization of juvenile crab[J].Feed Ind,2013,(16):52-54.
[16]杨志欣,程静,张文君,等.苦参总黄酮磷脂复合物的制备及优化[J].中药新药与临床药理,2018,(3):342-346.Yang ZX,Cheng J,Zhang WJ,et al.Preparation and characterization of total flavonoids phospholipid complex from sophora flavenscens[J].Trad Chin Drug Res Clin Pharm,2018,(3):342-346.
[17]关润伶,邹静,朱红.大豆卵磷脂的分离纯化研究进展[J].中国食品添加剂,2005,(5):44-47,59.Guan RL,Zhou J,Zhu H.Advance in separation and purification technology of soybean lecithin[J].Chin Food Add,2005,(5):44-47,59.
[18]陈玉江,殷涌光,李扬,等.高压脉冲电场作用于蛋黄卵磷脂提取过程的研究[J].食品科学,2006,(12):781-784.Chen YJ,Yin YG,Li Y,et al.Study on the effect of high pulsed electric fields on the process of extracting egg yolk lecithin[J].Food Sci,2006,(12):781-784.
[19]韩伟,吕金懋,陈惠丹,等.从蛋黄中提取卵磷脂的微波辅助萃取新工艺[J].机电信息,2009,(5):45-48.Han L,Lv JM,Chen HD,et al.Microwave-assisted extraction of lecithin from egg yolk[J].Electr Inform,2009,(5):45-48.
[20]彭述辉,黄利华,熊波,等.大豆卵磷脂分离纯化工艺的研究进展[J].大豆科技,2012,(4):29-32.Peng SH,Huang LH,Xiong B,et al.Advances in extraction and purification of soy lecithin[J].Soybean Technol,2012,(4):29-32.
[21]王二雷,宫新统,刘静波.蛋黄卵磷脂研究概况[J].食品工业科技,2010,(5):414-416,420.Wang EL,Gong XT,Liu JB,et al.Overview on study of egg yolk lecithin[J].Sci Technol Food Ind,2010,(5):414-416,420.
[22]刘颖,肖静静,李硕绵,等.蛋黄卵磷脂提取方法的研究[J].河北农业大学学报,2013,36(6):105-108.Liu Y,Xiao JJ,Li SM,et al.Study on the extraction methods of egg yolk lecithin[J].J Agric Univ Hebei,2013,36(6):105-108.
[23]Shah A,Akoh CC,Toledo RT,et al.Isolation of a phospholipid fraction from inedible egg[J].J Supercrit Fluid,2004,30(3):303-313.
[24]Gigliotti JC,Davenport MP,Beamer SK,et al.Extraction and characterisation of lipids from Antarctic krill(Euphausia superba)[J].Food Chem,2011,125(3):1028-1036.
[25]宋晓燕,周锦珂,李金华,等.超声强化提取蛋黄卵磷脂的工艺研究[J].中药材,2008,31(10):1572-1574.Song XY,Zhou JK,Li JH,et al.Study on ultrasonic enhanced extraction of egg yolk lecithin[J].Chin Herb Med,2008,31(10):1572-1574.
[26]黄群,麻成金,马美湖,等.超声波辅助提取鹌鹑蛋黄卵磷脂研究[J].食品科学,2006,27(11):297-300.Huang Q,Ma CJ,Ma MH,et al.Study on extraction of lecithin from quail's egg yolk with ultrasonic[J].Food Sci,2006,27(11):297-300.
[27]范劲松,李斌,徐保立,等.超临界CO2对蛋黄卵磷脂提取影响因素的探讨[J].粮油加工,2010,(5):103-106.Fan JS,Li B,Xu BL,et al.Discussion on the factors affecting the extraction of lecithin from egg yolk by supercritical CO2[J].Cere Oil Prod,2010,(5):103-106.
[28]刘博,陈开勋,陈渭萍,等.肉豆蔻超临界二氧化碳萃取工艺及其精油的GC-MS分析研究[J].香料香精化妆品,2003,(4):17-19.Liu B,Chen KX,Chen WP,et al.Study on extraction of nutmeg by supercritical carbon dioxide and GC-MS analytical[J].Flav Fragr Cosmet,2003,(4):17-19.
[29]林影影,阳向波,纪奇森,等.超临界CO2与乙醇结合工艺制备蛋黄油及其质量控制[J].亚太传统医药,2016,(23):28-31.Lin YY,Yang XB,Ji QS,et al.Preparation of egg yolk oil by supercritical CO2 and ethanol combined process and its quality control[J].Asia-Pacific Trad Med,2016,(23):28-31.
[30]张民,胡云翔,孙学文,等.超(亚)临界丙烷萃取蛋黄卵磷脂-由实验室走向工业化[J].食品工业科技,2016,(1):152-154,157.Zhang M,Hu YX,Sun XW,et al.Supercritical(subcritical)extraction of egg yolk lecithinwith propane-from lab scale to industry pilot[J].Sci Technol Food Ind,2016,(1):152-154,157.
[31]曾虹燕,方芳,蒋丽娟.超临界CO2萃取大豆油与大豆磷脂工艺条件研究[J].生物技术,2003,13(2):37-39.Ceng HY,Fang F,Jiang LJ.Studies on the technology of extracting soybean oil and phospholipid with supercritical CO2[J].Biotechnology,2003,13(2):37-39.
[32]夏杨毅,李洪军,鲁言文,等.超临界CO2高效萃取卵黄磷脂的研究[J].粮油加工与食品机械,2004,(8):46-47,50.Xia YY,Li HJ,Lu YW,et al.Study on efficient extraction of egg yolk lecithin with superoritical CO2[J].Grain Oil Process Food Mach,2004,(8):46-47,50.
[33]Teberikler L,Koseoglu S,Akgerman A.Selective extraction of phosphatidylcholine from lecithin by supercritical carbon dioxide/ethanol mixture[J].J Am Oil Chem Soc,2001,78(2):115-120.
[34]王秀嫔,李培武,张文,等.超声提取正相高效液相色谱法测定大豆及大豆油中的磷酸甘油酯[J].分析测试学报,2011,(5):527-531.Wang XP,Li PW,Zhang W,et al.Detection of phospholipid compounds in soybean and soybean oil samples using ultrasonic extraction and normal-phase HPLC with UV detection[J].J Instrum Anal,2011,(5):527-531.
[35]曲怀坤.蛋黄卵磷脂的提取方法研究[J].山东食品发酵,2011,(3):18-21.Qu HK.The study on extraction of egg yolk lecithin[J].Shandong Food Ferment,2011,(3):18-21.
[36]王磊,高正松,万辉,等.氧化铝吸附提纯大豆卵磷脂的工艺研究[J].食品工业科技,2013,(6):296-298.Wang L,Gao ZS,Wan H,et al.Purification process of soyabean lecithin by alumina adsorption method[J].Sci Technol Food Ind,2013,(6):296-298.
[37]Hoi DU,Lo S.Separation of phospholipids using a diethylaminoethyl-silica gel column and thin-layer chromatography[J].JChromatogr B,1986,(381):233-240.
[38]徐晨.大豆卵磷脂的提纯研究[J].天然产物研究与开发,1998,(2):75-78.Xu C.Research of soybean lecithin extraction[J].Nat Prod Res Dev,1998,(2):75-78.
[39]吴汉东,佟伟.高纯度蛋黄卵磷脂的提取工艺研究[J].安徽农业科学,2010,38(14):7537-7538.Wu HD,Tong W.Study on the extraction technology of high-purity egg yolk lecithin[J].J Anhui Agric Sci,2010,38(14):7537-7538.
[40]Barry KM,Dinan TG,Kelly PM.Pilot scale production of a phospholipid-enriched dairy ingredient by means of an optimised integrated process employing enzymatic hydrolysis,ultrafiltration and super-critical fluid extraction[J].Innov Food Sci Emerg Technol,2017,(41):301-306.
[41]徐晓斌,李俊玲,杨阳,等.南极磷虾油酶解法提取工艺研究[J].中国油脂,2015,(5):5-8.Xu XB,Li JL,Yang Y,et al.Enzymatic extraction of Antarctic krill oil[J].China Oil Fat,2015,(5):5-8.
[42]赵彦巧,李建颖,吴子健,等.酶解超声辅助卵磷脂的提取工艺[J].食品研究与开发,2012,(11):93-96.Zhao YQ,Li JY,Wu ZJ,et al.Enzymolysis ultrasonic-assisted extraction of lecithin from egg yolk powder[J].Food Res Dev,2012,(11):93-96.
[43]李才明,许学勤,王卫芬,等.鲜鸡蛋蛋黄酶法提油工艺的研究[J].食品与发酵工业,2008,(8):83-85.Li CM,Xu XQ,Wang WF,et al.The technology of the enzymatic extraction oil from fresh egg yolk[J].Food Ferm Ind,2008,(8):83-85.
[44]Navidghasemizad S,Temelli F,Wu J.Moisture impact on extractability of phospholipids from leftover egg yolk after enzymatic treatment using supercritical carbon dioxide[J].Food Bioprod Process,2015,(94):473-481.
[45]Konrad G,Kleinschmidt T,Lorenz C.Ultrafiltration of whey buttermilk to obtain a phospholipid concentrate[J].Inter Dair J,2013,30(1):39-44.
[46]Barry KM,Dinan TG,Kelly PM.Selective enrichment of dairy phospholipids in a buttermilk substrate through investigation of enzymatic hydrolysis of milk proteins in conjunction with ultrafiltration[J].Int Dair J,2017,(68):80-87.
[47]郭勍,徐桂云,常理文.大豆磷脂组成的薄层色谱分析[J].分析化学,1998,(1):81-84.Guo Q,Xu GY,Chang LW.Analysis of soybean phospholipids by thin-layer chromatography[J].Chin J Anal Chem,1998,(1):81-84.
[48]马辰,段宏瑾.大豆磷脂中磷脂类成分的含量测定[J].中国中药杂志,1999,(11):31-32.Ma C,Duan HJ.Determination of phospholipids in soybean phospholipids[J].China J Chin Mater Med,1999,(11):31-32.
[49]张卓勇,罗茜,郭黎平.吉林大豆中卵磷脂的成分提取与分析[J].东北师大学报(自然科学版),2001,(2):37-43.Zhang ZY,Luo Q,Guo LP.Extraction and analysis of lecithin components in soybeans in Jilin province[J].J Northeast Norm Univ(Nat Sci Ed),2001,(2):37-43.
[50]鲍风,张克,文德成.大豆磷脂组成的研究Ⅰ.磷脂组成的薄层色谱分析[J].生物化学与生物物理学报,1981,(4):373-378.Bao F,Zhang K,Wen DC.Studies on the composition of soybean phospholipids I.Thin layer chromatography analysis of phospholipid composition[J].J Biochem Biophys,1981,(4):373-378.
[51]Christie WW,Urwin RA.Separation of lipid classes from plant tissues by high performance liquid chromatography on chemically bonded stationary phases[J].J High Resolut Chromatogr,1995,18(2):97-100.
[52]Mawatari S,Okuma Y,Fujino T.Separation of intact plasmalogens and all other phospholipids by a single run of high-performance liquid chromatography[J].Anal Biochem,2007,370(1):54-59.
[53]李国辉,钟其顶,王道兵,等.HPLC法测定大豆磷脂及其保健品中PC、PI、PE[J].食品研究与开发,2015,(6):67-70.Li GH,Zhong QD,Wang DB,et al.Determination of the concentrations of phosphatidylcholine,phosphatidyl ethanolamine and phosphatidylinositol in soybean phospholipids and health care products by HPLC[J].Food Res Dev,2015,(6):67-70.
[54]Yamagishi T,Akiyama H,Kimura S,et al.Quantitative determination of phosphatidylcholine by an HPLC-RI system[J].J Am Oil Chem Soc,1989,66(12):1801-1808.
[55]Rhee JS,Shin MG.Analysis of phosphatidylcholine in soy lecithins by HPLC[J].J Am Oil Chem Soc,1982,59(2):98-99.
[56]Der Meeren PV,Vanderdeelen J,Huys M,et al.Simple and rapid method for high-performance liquid chromatographic separation and quantification of soybean phospholipids[J].J Chromatogr A,1988,447(S):436-442.
[57]刘静波,常皓,王二雷,等.高效液相色谱法检测蛋黄卵磷脂中的磷脂酰胆碱[J].吉林大学学报(工学版),2012(S1):449-453.Liu JB,Chang H,Wang EL,et al.Phosphatidylcholine of egg yolk lecithin detection using high performance liquid chromatography(HPLC)[J].J Jilin Univ(Eng Technol Ed),2012(S1):449-453.
[58]章慧芳,陆娅.大豆磷脂中卵磷脂检测方法的研究[J].中国油脂,2007,32(7):70-73.Zhang HF,Lu Y.Determination of soybean phosphatidylcholine[J].China Oil Fat,2007,32(7):70-73.
[59]Rodr??guez-Bernaldo DQA,López-Hernández J,Simal-Lozano J.Separation of phospholipid classes in sea urchin,Paracentrotus lividus by high-performance liquid chromatography[J].J Chromatogr B,2002,770(1):71-75.
[60]Hanson VL,Park JY,Osborn TW,et al.High-performance liquid chromatographic analysis of egg yolk phospholipids[J].J Chromatogr A,1981,205(2):393-400.
[61]曹栋.HPLC-ESLD法分离测定大豆磷脂酰胆碱[J].中国油脂,2005,30(12):43-45.Cao D.Separation and determination of soybean phosphatidylcholine in soybean phospholipid by HPLC-ELSD[J].China Oil Fat,2005,30(12):43-45.
[62]Balazs PE,Schmit PL,Szuhaj BF.High-performance liquid chromatographic separations of soy phospholipids[J].J Am Oil Chem Soc,1996,73(2):193-197.
[63]Mcnabb TJ,Cremest A.High-performance liqued chromatography evaporative light-scattering detector techniques for neutral,polar,and acidic lipid classes a review of methods and detector models[J].Semin Food Anal,1999,4(1):53-69.
[64]王琦,薛长湖,徐杰,等.HPLC-ELSD法测定几种水产品卵及生殖腺中磷脂的组成[J].分析仪器,2012,(5):18-22.Wang Q,Xue CH,Xu J,et al.Determination of phospholipids in egg/gonad from several aquatic products by HPLC-ELSD[J].Anal Instrum,2012,(5):18-22.
[65]朱瑶,陈慧民,卢航,等.刺参性腺中6种磷脂含量的HPLC-ELSD分析[J].大连海洋大学学报,2015,30(4):422-425.Zhu Y,Chen HM,Lu H,et al.HPLC-ELSD analysis of six phospholipids in the gland of sea cucumber[J].J Dalian Ocean Univ,2015,30(4):422-425.
[66]Zhang Y,Cn YYCZ,Ren Q,et al.Quantification of soybean phospholipids in soybean degummed oil residue by HPLC with evaporative light scattering detection[J].J Liq Chromatogr Relat Technol,2017,28(9):1333-1343.
[67]陈康,戴志远,沈清,等.响应面法提取南极磷虾磷脂及其分子种组成的测定[J].南方水产科学,2017,13(3):104-112.Chen K,Dai ZY,Shen Q,et al.Extraction of phospholipid from Euphausia superba by response surface method and determination of phospholipid molecular species[J].South China Fish Sci,2017,13(3):104-112.
[68]Ali AH,Zou X,Huang J,et al.Profiling of phospholipids molecular species from different mammalian milk powders by using ultra-performance liquid chromatography-electrospray ionization-quadrupole-time of flight-mass spectrometry[J].J Food Compos Anal,2017,(1):143-154.
[69]Liang P,Li R,Sun H,et al.Phospholipids composition and molecular species of large yellow croaker(Pseudosciaena crocea)roe[J].Food Chem,2018,(245):806-811.
[70]周瑢,黏慧青,陈华勇,等.磷脂检测新技术[J].现代科学仪器,2008,(1):61-64.Zhou Rian HQ,Chen HR,et al.Phospholipids analysis by new technology[J].Mod Sci Instrum,2008,(1):61-64.
[71]刘纯友,马美湖,王庆玲,等.核磁共振技术在食品脂质研究中的应用新进展[J].食品工业科技,2017,38(12):342-346.Liu CY,Ma MH,Wang QL,et al.New advances of application of nuclear magnetic resonance technology in food lipid research[J].Sci Technol Food Ind,2017,38(12):342-346.
[72]庞思勉,张明霞,姬红萍.31P核磁共振光谱法测定坚果类食品中的6种磷脂[J].理化检验-化学分册,2016,52(1):44-46,47.Pang SM,Zhang MX,Ji HP.Determination of 6 phospholipids in nuts by31P-NMR[J].Phys Test Chem Anal B,2016,52(1):44-47.
[73]崔常乐,滕英来,汪勇,等.核磁共振磷谱内标法测定磷脂酰胆碱的含量[J].中国粮油学报,2016,31(5):158-162.Cui CL,Teng YL,Wang Y,et al.Quantitative determination of phosphatidylcholine by 31P nuclear magnetic resonance(31P-NMR)with internal standard method[J].J Chin Cereal Oil Assoc,2016,31(5):158-162.
[74]俞乐,丛芳,王兴国,等.不同来源大豆毛油磷脂组成的核磁检测及磷脂酸含量比较[J].中国油脂,2017,(1):130-133.Yu L,Cong F,Wang XG,et al.Determination of phospholipids composition in crude soybean oil from different sources by nuclear magnetic resonance and comparison of phosphatidic acid content[J].China Oil Fat,2017,(1):130-133.
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