邻苯二甲酸酯类毒性及检测方法研究进展
|
摘要
邻苯二甲酸酯类(Phthalic Acid Esters, PAEs)是重要的工业添加剂之一,可作为塑料工业的增塑剂、软化剂以及化工业的增香剂、成膜剂等,其制品应用广泛.但因其为一类环境激素类持久性有机污染物,对生物个体发育、新陈代谢等产生不利影响,并可沿食物链传递,危害到生态系统乃至人类.本文通过总结邻苯二甲酸酯类物质的不同暴露途径、毒性危害及检测方法等方面的国内外研究进展,指出了现有研究的不足和未来研究趋势,以期为进一步研究邻苯二甲酸酯类对生态环境的影响提供参考.
Phthalic acid esters(PAEs), classified as an important group of industrial additives, can be used as plasticizers and softeners in the plastics industry, also applied as flavoring agents and film-forming agents in the chemical industry. With the properties as one of persistent organic pollutants of environmental hormones, PAEs induce negative effects on biological reproductive development, metabolism. Consequently this effect can endanger the ecosystem along food chain. This paper summarizes the international research progress in the aspects of PAEs′ different exposure trend and intends to provide some reference for more further studies of the effects of PAEs on ecological environment.
Phthalic acid esters(PAEs), classified as an important group of industrial additives, can be used as plasticizers and softeners in the plastics industry, also applied as flavoring agents and film-forming agents in the chemical industry. With the properties as one of persistent organic pollutants of environmental hormones, PAEs induce negative effects on biological reproductive development, metabolism. Consequently this effect can endanger the ecosystem along food chain. This paper summarizes the international research progress in the aspects of PAEs′ different exposure trend and intends to provide some reference for more further studies of the effects of PAEs on ecological environment.
引文
[1] 陈洪涛,王力清,黄翠莉,等.邻苯二甲酸酯毒理学研究进展[J].食品与机械,2012,28(5):251-254.CHEN H T,WANG L Q,HUANG C L,et al.Advances in toxicology of phthalates [J].Food and Machinery,2012,28(5):251 -254(in Chinese).
[2] 宋雪英,崔小维,李嘉康,等.邻苯二甲酸酯类塑化剂的土壤生态毒理学研究进展[J].生态环境学报,2016,25(11):1885-1890.SONG X Y,CUI X W,LI J K,et al.Advances in soil ecological toxicology of phthalate plasticizers [J].Journal of Ecological Environment,2016,25(11):1885-1890(in Chinese).
[3] QY C,CH M,QT W,et al.The status of soil contamination by semivolatile organic chemicals (SVOCs) in China:A review[J].Science of the Total Environment,2008,389(2):209-224.
[4] 国家环境保护总局,国家质量监督检验检疫总局.地表水环境质量标准:GB 3838-2002[S].北京中国环保产业,2002.State environmental protection administration,general administration of quality supervision,inspection and quarantine.Environmental quality standards for surface water:GB 3838-2002[S].Beijing China Environmental Protection Industry,2002(in Chinese).
[5] FROMME T L,PILOTY M,GEBHART H,et al.Occurrence of phthalates and musk fragrances in indoor air and dust from apartments and kindergartens in Berlin (Germany)[J].Indoor Air,2014,14:188-195.
[6] KERESZTES S,TATAR E,CZEGENY Z,et al.Study on the leaching of phthalates from polyethylene terephthalate bottles into mineral water[J].Science of the Total Environment,2013,458-460(3):451-458.
[7] 杨悠悠,谢云峰,田菲菲,等.常见食品中邻苯二甲酸酯类增塑剂含量及食品包装材料中邻苯二甲酸酯类增塑剂迁移量的测定[J].色谱,2013,31(7):674-678.YANG Y Y,XIE Y F,TIAN F F,et al.The common phthalate plasticizers in the food and food packaging materials of phthalic acid esters plasticizer migration quantity measurement[J].Journal of Chromatography,2013,31 (7):674-678(in Chinese).
[8] 郭永梅.有关邻苯二甲酸酯类增塑剂在食品包装材料中应用的法规[J].塑料助剂,2012,16(4):18-20.GUO Y M.Regulations on the application of phthalate plasticizers in food packaging materials[J].Plastic Additives,2012,16(4):18-20(in Chinese).
[9] SIOEN I,FIERENS T,VAN H M,et al.Phthalates dietary exposure and food sources for Belgian preschool children and adults[J].Environment International,2012,48:102-108.
[10] 刘乃榕,王少鹏,杨光.邻苯二甲酸酯类毒性作用研究进展[J].大连医科大学学报,2016,38(5):492-495.LIU N R,WANG S P,YANG G.Research progress on toxicity of phthalates [J].Journal of Dalian Medical University,2016,38(5):492-495(in Chinese).
[11] 陈泱,沈好文,裘婧,等.气相色谱-质谱联用法检测药品包装用聚氯乙烯类硬片材料中5种邻苯二甲酸酯类塑化剂的研究[J].药物分析杂志,2014,34(9):1650-1653.CHEN Y,SHEN H W,QIU J,et al.gas chromatography - mass spectrometry detection ia pharmaceutical packaging PVC plate materials of 5 kinds of phthalic acid esters plasticizer study [J].Journal of Pharmaceutical Analysis,2014,34(9):1650-1653(in Chinese).
[12] 逯元媛.浅析药用辅料对药品安全性的影响表现[J].科学咨询(科技·管理),2016,17(10):61-62.LU Y Y.A brief analysis of the impact of medical excipients on drug safety [J].Scientific Consultation (Science,Technology,Management),2016,17(10):61-62(in Chinese).
[13] BLOUNT B C,MILGRAM K E,SILVA M J,et al.Quantitative detection of eight phthalate metabolites in human urine using HPLC-APCI-MS/MS[J].Analytical Chemistry,2000,72(17):4127-4134.
[14] 杜庆璋.五类玩具中重金属及邻苯二甲酸酯类(PAEs)的暴露风险评价[D].上海:华东理工大学,2015.DU Q Z.Exposure risk assessment of heavy metals and PAEs in five types of toys [D].Shanghai:East China University of Technology,2015(in Chinese).
[15] FREE C M,JENSEN O P,MASON S A,et al.High-levels of microplastic pollution in a large,remote,mountain lake[J].Marine Pollution Bulletin,2014,85(1):156-163.
[16] AUTA H S,EMENIKE C UFAUZIAH S H.Distribution and importance of microplastics in the marine environment:A review of the sources,fate,effects,and potential solutions[J].Environment International,2017,102:165-176.
[17] JABEEN K,SU L,LI J,et al.Microplastics and mesoplastics in fish from coastal and fresh waters of China[J].Environment Pollution,2017,221:141-149.
[18] BONANNO G,ORLANDO-BONACA M.Ten inconvenient questions about plastics in the sea[J].Environmental Science & Policy,2018,85:146-154.
[19] 刘册家,向兰,杨美华.我国环境中邻苯二甲酸酯类分布状况研究进展[J].中国现代中药,2008,10(3):37-40.LIU C J,XIANG L,YANG M H.Research progress on the distribution of phthalates in China′s environment[J].Modern Chinese Medicine,2008,10(3):37-40(in Chinese).
[20] 王超英,李碧芳,郝金声,等.红枫湖及其污染源中邻苯二甲酸酯类化合物的测定[J].贵州教育学院学报,2006,17(4):42-44.WQANG C Y,LI B F,HAO J S,et al.Determination of phthalate esters in Hongfeng Lake and its pollution source[J].Journal of Guizhou Education Institute (Natural Science),2006,17(4):42-44(in Chinese).
[21] XIONG X,ZHANG K,CHEN X,et al.Sources and distribution of microplastics in China′s largest inland lake - Qinghai Lake[J].Environment Pollution,2018,235:899-906.
[22] DRIS R,GASPERI J,SAAD M,et al.Synthetic fibers in atmospheric fallout:A source of microplastics in the environment?[J].Marine Pollution Bulletin,2016,104(1-2):290-293.
[23] KARLSSON T M,ARNEBORG L,BROSTROM G,et al.The unaccountability case of plastic pellet pollution[J].Marine Pollution Bulletin,2018,129(1):52-60.
[24] LESLIE H A,BRANDSMA S H,VAN VELZEN M J,et al.Microplastics en route:Field measurements in the Dutch river delta and Amsterdam canals,wastewater treatment plants,North Sea sediments and biota[J].Environment International,2017,101:133-142.
[25] GASPERI J,DRIS R,BONIN T,et al.Assessment of floating plastic debris in surface water along the Seine River[J].Environment Pollution,2014,195:163-166.
[26] SRUTHY S,RAMASAMY E V.Microplastic pollution in Vembanad Lake,Kerala,India:The first report of microplastics in lake and estuarine sediments in India[J].Environment Pollution,2017,222:315-322.
[27] GROSS M.Plastic waste is all at sea[J].Current Biology,2013,23(4):135-137.
[28] GANI P,SUNAR N M,MATIAS-PERALTA H,et al.Extraction of hydrocarbons from freshwater green microalgae (Botryococcus sp.) biomass after phycoremediation of domestic wastewater[J].International Journal of Phytoremediation,2017,19(7):679-685.
[29] CHAN H W,CHAN C M,ANG P O,et al.Integrated biosorption and photocatalytic oxidation treatment of di(2-ethylhexyl)phthalate[J].Journal of Applied Phycology,2007,19(6):745-753.
[30] 邱海源,王宪.邻苯二甲酸酯对海洋藻类的致毒效应[J].厦门大学学报(自然版),2005,44(2):294-296.QIU H Y,WANG X.Toxic effects of phthalates on Marine algae [J].Journal of xiamen university (nature),2005,44(2):294-296(in Chinese).
[31] JONSSON S,BAUN A.Toxicity of mono-and diesters of o-phthalic esters to a crustacean,a green alga,and a bacterium[J].Environmental Toxicology & Chemistry,2010,22(12):3037-3043.
[32] GU S,ZHENG H,XU Q,et al.Comparative toxicity of the plasticizer dibutyl phthalate to two freshwater algae[J].Aquatic Toxicology,2017,191:122-130.
[33] 梁智.不同增塑剂对短凯伦藻的生长抑制作用及其机理研究[D].山东:中国海洋大学,2015.LIANG Z.Inhibition effect of different plasticizers on growth and its mechanism of short-kelon algae [D].Shangdong:China Ocean University,2015(in Chinese).
[34] 别聪聪.邻苯二甲酸二丁酯对短裸甲藻的化感抑制机理研究[D].山东:中国海洋大学,2011.BIE C C.Study on the mechanism of dibutyl phthalate inhibiting chlorophyll chemosensitization [D].Shangdong:China Ocean University,2011(in Chinese).
[35] 别聪聪,李锋民,李媛媛,等.邻苯二甲酸二丁酯对短裸甲藻活性氧自由基的影响[J].环境科学,2012,33(2):442-447.BIE C C,LI F M,LI Y Y,et al.Effects of dibutyl phthalate on reactive oxygen free radicals in brassica campestris [J].Environmental Science,2012,33(2):442-447(in Chinese).
[36] HEINDLER F M,ALAJMI F,HUERLIMANN R,et al.Toxic effects of polyethylene terephthalate microparticles and Di(2-ethylhexyl)phthalate on the calanoid copepod,Parvocalanus crassirostris[J].Ecotoxicology Environmental Safety,2017,141:298-305.
[37] 黄国兰,孙红文.邻苯二甲酸二丁酯对大型蚤(Daphniamagna)的毒性作用研究[J].环境化学,1998,17(5):428-433.HUANG G L,SUN H W.Study on the toxicity of dibutyl phthalate on Daphniamagna[J].Environmental Chemistry,1998,17(5):428-433(in Chinese).
[38] LU Y,LIN MAITKEN R J.Exposure of spermatozoa to dibutyl phthalate induces abnormal embryonic development in a marine invertebrate Galeolaria caespitosa (Polychaeta:Serpulidae)[J].Aquatic Toxicology,2017,191:189-200.
[39] 刘伟杰,段舜山.邻苯二甲酸二丁酯对多刺裸腹溞生长繁殖的影响[J].生态科学,2011,30(3):229-235.LIU W J,DUAN S S.Effects of dibutyl phthalate on growth and propagation of daphnia daphnia dorsalis [J].Ecological Science,2011,30(3):229-235(in Chinese).
[40] 王金霞,席贻龙,刘晓波,等.邻苯二甲酸二丁酯对多刺裸腹溞的毒性[J].生态学杂志,2009,28(7):1335-1339.WANG J X,XI Y L,LIU X B,et al.Toxicity of dibutyl phthalate to DPC [J].Journal of Ecology,2009,28(7):1335-1339(in Chinese).
[41] 杜静,于明曦,宋广军,等.基于双壳贝类指示的海洋微塑料污染监测与毒理学研究进展[J].生态学杂志,2018,37(7):2205-2212.DU J,YU M X,SONG G J,et al.Research advances on monitoring and toxicology of microplastic pollution in marine as indicated by bivalves[J].Chinese Journal of Ecology,2018,37(7):2205-2212(in Chinese).
[42] 苏洪波,王兴强,曹梅,等.PAEs对四角蛤蜊毒性和免疫的影响[J].淮海工学院学报.自然科学版,2015,24(4):83-86.SU H B,WANG X Q,CAO M,et al.PAEs on the toxicity and immunity of clams at four corners [J].Journal of Huaihai Institute of Technology.Nature Science Edition,2015,24(4):83-86(in Chinese).
[43] DIGKA N,TSANGARIS C,TORRE M,et al.Microplastics in mussels and fish from the Northern Ionian Sea[J].Marine Pollution Bulletin,2018,135:30-40.
[44] 丁金凤,李景喜,孙承君,等.双壳贝类消化系统中微塑料的分离鉴定及应用研究[J].分析化学,2018,46(5):680-697.DING J F,LI J X,SUN C J,et al.Separation,identification and application of microplastics in digestive system of bivalves[J].Analytical Chemistry,2018,46(5):680-697(in Chinese).
[45] HAN X N,LIU D C.Detection of the toxic substance dibutyl phthalate in Antarctic krill[J].Antarctic Science,2017,29(6):511-516.
[46] 李潇.邻苯二甲酸酯类在养殖鱼类体内含量分析及其胚胎毒性研究[D].广东:暨南大学,2007.LI X.Analysis of phthalates in cultured fish and studies on embryo toxicity [D].Guangdong:Jinan University,2007(in Chinese).
[47] DONG X,QIU X,MENG S,et al.Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels[J].Chemosphere,2018,193:313-320.
[48] SUN G,LIU K.Developmental toxicity and cardiac effects of butyl benzyl phthalate in zebrafish embryos[J].Aquatic Toxicology,2017,192:165-170.
[49] 李文英,熊丽,刘荣,等.邻苯二甲酸二丁酯(DBP)对斑马鱼(Brachydanio rerio)生理生化特性的影响[J].生态毒理学报,2007,2(1):117-122.LI W Y,XIONG L,LIU R,et al.Effects of dibutyl phthalate (DBP) on physiological and biochemical characteristics of zebrafish (Brachydanio rerio)[J].Ecological Toxicology,2007,2 (1):117-122(in Chinese).
[50] ZHU Y,HUA R,ZHOU Y,et al.Chronic exposure to mono-(2-ethylhexyl)-phthalate causes endocrine disruption and reproductive dysfunction in zebrafish[J].Environmental Toxicology & Chemistry,2016,35(8):2117-2124.
[51] 张威振,赖子尼,赵李娜,等.环境中邻苯二甲酸酯类污染物的研究进展[J].中国渔业质量与标准,2014,4(4):13-20.ZHANG W Z,LAI Z N,ZHAO L N,et al.Research progress on phthalate pollutants in the environment [J].Chinese Fishery Quality and Standards,2014,4(4):13-20(in Chinese).
[52] 李学彬,陈莉,吴丹,等.邻苯二甲酸二乙基己酯对金鲫鱼脑组织和肾脏的氧化损伤作用[J].化学与生物工程,2008,25(4):57-59.LI X B,CHEN L,WU D,et al.Effects of diethylhexyl phthalate on oxidative damage of brain tissue and kidney of golden carp [J].Chemical and Biological Engineering,2008,25(4):57-59(in Chinese).
[53] 陈莉,李学彬,杨光涛,等.邻苯二甲酸二乙基己酯(DEHP)对金鲫鱼脑细胞DNA的损伤[J].生态毒理学报,2008,3(2):144-148.CHEN L,LI X B,YANG G T,et al.Damage of diethylhexyl phthalate (DEHP) to brain cell DNA of golden carp [J].Ecological Toxicology,2008,3(2):144-148(in Chinese).
[54] NUGEGODA D,KIBRIA G.Effects of environmental chemicals on fish thyroid function:Implications for fisheries and aquaculture in Australia[J].General and Comparative Endocrinology,2017,244:40-53.
[55] 孙翠竹,李富云,涂海峰,等.邻苯二甲酸酯类对水生食物链的影响研究进展[J].生态毒理学报,2016,11(6):12-24.SUN C Z,LI F Y,TU H F,et al.Research progress on effects of phthalates on aquatic food chain [J].Ecological Toxicology,2016,11(6):12-24(in Chinese).
[56] CZERNYCH R,CHRANIUK M,ZAGO■D■ON P,et al.Characterization of estrogenic and androgenic activity of phthalates by the XenoScreen YES/YAS in vitro assay[J].Environmental Toxicology & Pharmacology,2017,53:95-104.
[57] GAO H T,XU R,CAO W X,et al.Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats[J].Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association,2017,101:94.
[58] 王心.邻苯二甲酸二-(2-乙基己基)酯的雌性生殖毒性研究[D].陕西:第四军医大学,2009.WANG X.Study on female reproductive toxicity of di-(2-ethylhexyl) phthalate [D].Shangxi:Fourth Military Medical University,2009(in Chinese).
[59] GIRIBABU N,REDDY P S.Protection of male reproductive toxicity in rats exposed to di-n-butyl phthalate during embryonic development by testosterone[J].Biomedicine & Pharmacotherapy,2017,87:355-365.
[60] GAO H T,XU R,CAO W X,et al.Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats[J].Food and Chemical Toxicology,2017,101:94-104.
[61] 柳春红,孙远明,杨艺超,等.邻苯二甲酸酯类增塑剂的污染及暴露评估现状[J].现代食品科技,2012,28(3):339-341.LIU C H,SUN Y M,YANG Y C,et al.Status of pollution and exposure assessment of phthalate plasticizers [J].Modern Food Technology,2012,28(3):339-341(in Chinese).
[62] JIANG L,WANG L,FANG T,et al.Disruption of ergosterol and tryptophan biosynthesis,as well as cell wall integrity pathway and the intracellular pH homeostasis,lead to mono-(2-ethylhexyl)-phthalate toxicity in budding yeast[J].Chemosphere,2018,206:643-654.
[63] KLUWE W M.Overview of phthalate ester pharmacokinetics in mammalian species[J].Environmental Health Perspectives,1982,45(45):3-9.
[64] BUCKNER S L,PRUITT A N,THOMAS C N,et al.Di-N-octylphthalate acts as a proliferative agent in murine cell hepatocytes by regulating the levels of TGF-beta and pro-apoptotic proteins[J].Food and Chemical Toxicology,2018,111:166-175.
[65] FARZANEHFAR V,NADERI N,KOBARFARD F,et al.Determination of dibutyl phthalate neurobehavioral toxicity in mice[J].Food and Chemical Toxicology,2016,94:221-226.
[66] TAN S,WANG D,CHI Z,et al.Study on the interaction between typical phthalic acid esters (PAEs) and human haemoglobin (hHb) by molecular docking[J].Environmental Toxicology and Pharmacology,2017,53:206-211.
[67] JUREWICZ J,HANKE W.Exposure to phthalates:reproductive outcome and children health.A review of epidemiological studies[J].International Journal of Occupational Medicine and Environmental Health,2011,24(2):115-141.
[68] SWAN S H,MAIN K M,LIU F,et al.Decrease in anogenital distance among male infants with prenatal phthalate exposure[J].Environmental Health Perspectives,2005,113(8):1056-1061.
[69] ZHANG J J,SHU W Q.Progress in phthalate ester toxicity in the female reproductive system[J].Journal of Hygiene Research,2005,34(4):496-498.
[70] SINGH N,DALAL VKUMAR P.Structure based mimicking of Phthalic acid esters (PAEs) and inhibition of hACMSD,an important enzyme of the tryptophan kynurenine metabolism pathway[J].International Journal of Biological Macromolecules,2018,108:214-224.
[71] DEL BUBBA M,ANCILLOTTI C,CHECCHINI L,et al.Determination of phthalate diesters and monoesters in human milk and infant formula by fat extraction,size-exclusion chromatography clean-up and gas chromatography-mass spectrometry detection[J].Journal of Pharmaceutical and Biomedical Analysis,2018,148:6-16.
[72] 张蕴晖,陈秉衡,郑力行,等.人体生物样品中邻苯二甲酸酯类的含量[J].中华预防医学杂志,2003,37(6):429-434.ZHANG Y H,CHEN B H,ZHENG L X,et al.Contents of phthalates in human biological samples [J].Chinese journal of preventive medicine,2003,37(6):429-434(in Chinese).
[73] 何雪峰.测定水中邻苯二甲酸酯类化合物液液萃取法与固相萃取法的选择[J].绿色科技,2017,2(6):9-11.HE X F.Determination of the choice of liquid extraction method and solid phase extraction method for phthalates in water [J].Green Technology,2017,2(6):9-11(in Chinese).
[74] 刘铭雪,丁爱中,张波涛,等.水中邻苯二甲酸酯的分析检测[J].工业水处理,2015,35(10):12-16.LIU M X,DING A Z,ZHANG B T,et al.Analysis and detection of phthalate in water [J].Industrial Water Treatment,2015,35(10):12-16(in Chinese).
[75] FERNANDEZ-GONZALEZ V,MOSCOSO-PEREZ C,MUNIATEGUI-LORENZO S,et al.Reliable,rapid and simple method for the analysis of phthalates in sediments by ultrasonic solvent extraction followed by head space-solid phase microextraction gas chromatography mass spectrometry determination[J].Talanta,2017,162:648-653.
[76] 马燕玲,陈令新,丁养军,等.超声辅助分散液液微萃取-高效液相色谱测定水样中的4种邻苯二甲酸酯类增塑剂[J].色谱,2013,31(2):155-161.MA Y L,CHEN L X,DING Y J,et al.Determination of four phthalate plasticizers in water samples by ultrasound-assisted dispersive liquid microextraction - HPLC[J].Chromatography,2013,31 (2):155-161(in Chinese).
[77] 陈飞.分散液液微萃取-气相色谱法测定海水中的邻苯二甲酸酯[J].福建分析测试,2014,23(3):33-37.CHEN F.Determination of phthalates in seawater by dispersive liquid microextraction with gas chromatography [J].Fujian Analytical Test,2014,23(3):33-37(in Chinese).
[78] WANG J,HUANG S,WANG P,et al.Method development for the analysis of phthalate esters in tea beverages by ionic liquid hollow fibre liquid-phase microextraction and liquid chromatographic detection[J].Food Control,2016,67:278-284.
[79] SALAZAR-BELTRAN D,HINOJOSA-REYES L,RUIZ-RUIZ E,et al.Determination of phthalates in bottled water by automated on-line solid phase extraction coupled to liquid chromatography with UV detection[J].Talanta,2017,168:291-297.
[80] 胡锋,刘功斌,袁新龙.固相萃取—高效液相色谱法测定水中阿特拉津和2种邻苯二甲酸酯[J].干旱环境监测,2015,29(2):61-65.HU F,LIU G B,YUAN X L.Determination of atrazine and two phthalates in water by solid-phase extraction (HPLC)[J].Drought Environment Monitoring,2015,29(2):61-65(in Chinese).
[81] LIANG J,NING X A,KONG M,et al.Elimination and ecotoxicity evaluation of phthalic acid esters from textile-dyeing wastewater[J].Environ Pollut,2017,231(1):115-122.
[82] 沈斐,苏晓燕,李睿,等.固相萃取-气相色谱法测定水环境中邻苯二甲酸酯[J].中国环境监测,2014,30(1):150-153.SHEN F,SU X Y,LI R,et al.Determination of phthalates in water environment by solid-phase extraction and gas chromatography [J].China Environmental Monitoring,2014,30(1):150-153(in Chinese).
[83] ARTHUR C L,PAWLISZYN J.Solid phase microextraction with thermal desorption using fused silica optical fibers[J].Analytical Chemistry,1990,62(19):2145-2148.
[84] BANDFORUZI S R,HADJMOHAMMADI M R.Application of non-ionic surfactant as a developed method for the enhancement of two-phase solvent bar microextraction for the simultaneous determination of three phthalate esters from water samples[J].Journal of Chromatography A,2018,1561:39-47.
[85] FERN n-G l V,MOSCOSO-P 瘙嚍REZ C,MUNIATEGUI-LORENZO S,et al.Reliable,rapid and simple method for the analysis of phthalates in sediments by ultrasonic solvent extraction followed by head space-solid phase microextraction gas chromatography mass spectrometry determination[J].Talanta,2017,162:648-653.
[86] 张泽明,张洪海,李建龙,等.固相微萃取-气相色谱-质谱联用测定海水与沉积物中邻苯二甲酸酯类污染物[J].分析化学,2017,45(3):348-356.ZHANG Z M,ZHANG H H,LI J L,et al.Determination of phthalates in seawater and sediments by solid-phase microextraction - gas chromatography - mass spectrometry[J].Analytical Chemistry,2017,45(3):348-356(in Chinese).
[87] 刘芃岩,高丽,申杰,等.固相微萃取-气相色谱法测定白洋淀水样中的邻苯二甲酸酯类化合物[J].色谱,2010,28(5):517-520.LIU P Y,GAO L,SHEN J,et al.Determination of phthalates in baiyangdian water samples by solid-phase microextraction and gas chromatography [J].Chromatography,2010,28(5):517-520(in Chinese).
[88] JORNET-MARTINEZ N,MUNOZ-ORTUNO M,MOLINER-MARTINEZ Y,et al.On-line in-tube solid phase microextraction-capillary liquid chromatography method for monitoring degradation products of di-(2-ethylhexyl) phthalate in waters[J].Journal of Chromatography A,2014,1347:157-160.
[89] 马鲲鹏,李琰,王冬究,等.水中邻苯二甲酸酯类化合物的固相膜萃取-气相质谱测定法[J].职业与健康,2015,31(13):1771-1773.MA K P,LI Y,WANG D J,et al.Determination of phthalates in water by solid-phase membrane extraction and gas phase mass spectrometry[J].Occupational and Health,2015,31(13):1771-1773(in Chinese).
[90] SI Q,LI F,GAO C,et al.Detection of phthalate esters in seawater by stir bar sorptive extraction and gas chromatography-mass spectrometry[J].Marine Pollution Bulletin,2016,108(1-2):163-170.
[91] MESDAGHINIA A,AZARI A,NODEHI R N,et al.Removal of phthalate esters (PAEs) by zeolite/Fe3O4:Investigation on the magnetic adsorption separation,catalytic degradation and toxicity bioassay[J].Journal of Molecular Liquids,2017,233:378-390.
[92] TANG M,WU Y,DENG D,et al.Development of an optical fiber immunosensor for the rapid and sensitive detection of phthalate esters[J].Sensors and Actuators B:Chemical,2018,258:304-312.
[93] YAN Z,HE M,CHEN B,et al.Magnetic covalent triazine framework for rapid extraction of phthalate esters in plastic packaging materials followed by gas chromatography-flame ionization detection[J].Journal of Chromatography A,2017,1525:32-41.
[94] LIANG Y R,ZHANG Z M,LIU Z J,et al.A highly sensitive signal-amplified gold nanoparticle-based electrochemical immunosensor for dibutyl phthalate detection[J].Biosens Bioelectron,2017,91:199-202.
[95] XU W,ZHANG X,HUANG W,et al.Synthesis of surface molecular imprinted polymers based on carboxyl-modified silica nanoparticles with the selective detection of dibutyl phthalate from tap water samples[J].Applied Surface Science,2017,426:1075-1083.
[96] 李健华,廖林波.浊点萃取-气相色谱法测定水中邻苯二甲酸酯类化合物[J].海峡药学,2016,28(1):45-48.LI J H,LIAO J B.Determination of phthalates in water by turbidimetric extraction and gas chromatography[J].Strait Pharmacology,2016,28(1):45-48(in Chinese).
[97] 沈斐,苏晓燕,李睿,等.固相萃取-气相色谱法测定水环境中邻苯二甲酸酯[J].中国环境监测,2014,30(1):150-153.SHEN F,SUN X Y,LI R,et al.Determination of phthalate esters in water by solid-phase extraction and gaschromatography[J].Environmental Monitoring in China,2014,30(1):150-153(in Chinese).
[98] 石凤琼,柯常亮,林钦,等.气相色谱-质谱法测定水产品中15种邻苯二甲酸酯类塑化剂的残留量[J].分析测试学报,2013,32(8):915-922.SHI F Q,KE C L,LIN Q,et al.Determination of residues of 15 phthalates plasticizers in aquatic products by gas chromatography-mass spectrometry [J].Journal of Analysis and Testing,2013,32 (8):915-922(in Chinese).
[99] 张泽明,张洪海,李建龙,等.固相微萃取-气相色谱-质谱联用测定海水与沉积物中邻苯二甲酸酯类污染物[J].分析化学,2017,45(03):348-356.ZHANG Z-M,ZHANG H-H,LI J-L,et al.Determination of phthalic acid esters in seawater and sediment by solid-phase microextraction and gas chromatography-mass spectrometry[J].Chinese Journal of Analytical Chemistry,2017,45(3):348-356.
[100] OTERO P,SAHA S K,MOANE S,et al.Improved method for rapid detection of phthalates in bottled water by gas chromatography-mass spectrometry[J].Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences,2015,997:229-235.
[101] 李玉玉,凌云,郭浩楠,等.气相色谱-质谱法测定水产品中24种邻苯二甲酸酯类化合物[J].分析测试学报,2013,32(4):408-413.LI Y Y,LING X,GUO H N,et al.Determination of 24 phthalates in aquatic products by gas chromatography-mass spectrometry [J].Journal of Analysis and Testing,2013,32(4):408-413(in Chinese).
[102] LEBEDEV A T,POLYAKOVA O V,MAZUR D M,et al.Detection of semi-volatile compounds in cloud waters by GCxGC-TOF-MS.Evidence of phenols and phthalates as priority pollutants[J].Environmental Pollution,2018,241:616-625.
[103] TARAFDAR A,SARKAR T K,CHAKRABORTY S,et al.Biofilm development of Bacillus thuringiensis on MWCNT buckypaper:Adsorption-synergic biodegradation of phenanthrene[J].Ecotoxicology and Environmental Safety,2018,157:327-334.
[104] GOMARA B,LEBRON-AGUILAR R,GONZALEZ M J,et al.Insight into the retention processes of phthalate metabolites on different liquid chromatography stationary phases for the development of improved separation methods[J].Journal of Chromatography A,2015,1423:86-95.
[105] 魏丽琼,呼世斌,刘书慧,等.QuEChERS-高效液相色谱法测定土壤中邻苯二甲酸酯[J].环境工程,2016,34(5):148-151.WEI L Q,HU S B,LIU S H,et al.Determination of phthalates in soil by quechers-high performance liquid chromatography[J].Environmental Engineering,2016,34(5):148-151(in Chinese).
[106] 曹攽,李云木子,马军,等.超声波萃取-高效液相色谱法测定土壤中邻苯二甲酸酯[J].岩矿测试,2011,30(2):178-181.CAO Y,LI Y M Z,MA JUN,et al.Determination of phthalates in soil by ultrasonic extraction-high performance liquid chromatography[J].Rock and Mineral Exploration,2011,30(2):178-181(in Chinese).
[107] VIDAL R B P,IBANEZ G AESCANDAR G M.A green method for the quantification of plastics-derived endocrine disruptors in beverages by chemometrics-assisted liquid chromatography with simultaneous diode array and fluorescent detection[J].Talanta,2016,159:336-343.
[108] 刘超.液质联用技术测定邻苯二甲酸酯类及酚类环境激素的研究[D].江西:南昌大学,2007.LIU C.A study on the determination of phthalic acid esters and phenol environmental hormones by combined liquid and mass technique [D].Jiangxi:Nanchang University,2007(in Chinese).
[109] RAMESH KUMAR A,SIVAPERUMAL P.Analytical methods for the determination of biomarkers of exposure to phthalates in human urine samples[J].TrAC Trends in Analytical Chemistry,2016,75:151-161.
[110] 王风红,芦春梅,胡婷婷,等.高效液相色谱-串联质谱法测定化妆品中的邻苯二甲酸酯[J].化学试剂,2015,37(2):135-138.WANG F H,LU C M,HU T T,et al.Determination of phthalate esters in cosmetics by high performance liquid chromatography-tandem mass spectrometry[J].Chemical Reagents,2015,37 (2):135-138(in Chinese).
[111] ZHOU Z,LI T,XU W,et al.Synthesis and characterization of fluorescence molecularly imprinted polymers as sensor for highly sensitive detection of dibutyl phthalate from tap water samples[J].Sensors and Actuators B:Chemical,2017,240:1114-1122.
[112] ZHU F,MAO CDU D.Time-resolved immunoassay based on magnetic particles for the detection of diethyl phthalate in environmental water samples[J].Science of Total Environment,2017,601-602:723-731.
[113] HE F,TIAN Y,XU Z,et al.Development of an immunochromatographic assay as a screen for detection of total phthalate acid esters in cooking oil[J].Journal of Toxicology and Environmental Health,PartA,2018,81(4):80-88.
[114] ZHU N,ZOU Y,HUANG M,et al.A sensitive,colorimetric immunosensor based on Cu-MOFs and HRP for detection of dibutyl phthalate in environmental and food samples[J].Talanta,2018,186:104-109.
[2] 宋雪英,崔小维,李嘉康,等.邻苯二甲酸酯类塑化剂的土壤生态毒理学研究进展[J].生态环境学报,2016,25(11):1885-1890.SONG X Y,CUI X W,LI J K,et al.Advances in soil ecological toxicology of phthalate plasticizers [J].Journal of Ecological Environment,2016,25(11):1885-1890(in Chinese).
[3] QY C,CH M,QT W,et al.The status of soil contamination by semivolatile organic chemicals (SVOCs) in China:A review[J].Science of the Total Environment,2008,389(2):209-224.
[4] 国家环境保护总局,国家质量监督检验检疫总局.地表水环境质量标准:GB 3838-2002[S].北京中国环保产业,2002.State environmental protection administration,general administration of quality supervision,inspection and quarantine.Environmental quality standards for surface water:GB 3838-2002[S].Beijing China Environmental Protection Industry,2002(in Chinese).
[5] FROMME T L,PILOTY M,GEBHART H,et al.Occurrence of phthalates and musk fragrances in indoor air and dust from apartments and kindergartens in Berlin (Germany)[J].Indoor Air,2014,14:188-195.
[6] KERESZTES S,TATAR E,CZEGENY Z,et al.Study on the leaching of phthalates from polyethylene terephthalate bottles into mineral water[J].Science of the Total Environment,2013,458-460(3):451-458.
[7] 杨悠悠,谢云峰,田菲菲,等.常见食品中邻苯二甲酸酯类增塑剂含量及食品包装材料中邻苯二甲酸酯类增塑剂迁移量的测定[J].色谱,2013,31(7):674-678.YANG Y Y,XIE Y F,TIAN F F,et al.The common phthalate plasticizers in the food and food packaging materials of phthalic acid esters plasticizer migration quantity measurement[J].Journal of Chromatography,2013,31 (7):674-678(in Chinese).
[8] 郭永梅.有关邻苯二甲酸酯类增塑剂在食品包装材料中应用的法规[J].塑料助剂,2012,16(4):18-20.GUO Y M.Regulations on the application of phthalate plasticizers in food packaging materials[J].Plastic Additives,2012,16(4):18-20(in Chinese).
[9] SIOEN I,FIERENS T,VAN H M,et al.Phthalates dietary exposure and food sources for Belgian preschool children and adults[J].Environment International,2012,48:102-108.
[10] 刘乃榕,王少鹏,杨光.邻苯二甲酸酯类毒性作用研究进展[J].大连医科大学学报,2016,38(5):492-495.LIU N R,WANG S P,YANG G.Research progress on toxicity of phthalates [J].Journal of Dalian Medical University,2016,38(5):492-495(in Chinese).
[11] 陈泱,沈好文,裘婧,等.气相色谱-质谱联用法检测药品包装用聚氯乙烯类硬片材料中5种邻苯二甲酸酯类塑化剂的研究[J].药物分析杂志,2014,34(9):1650-1653.CHEN Y,SHEN H W,QIU J,et al.gas chromatography - mass spectrometry detection ia pharmaceutical packaging PVC plate materials of 5 kinds of phthalic acid esters plasticizer study [J].Journal of Pharmaceutical Analysis,2014,34(9):1650-1653(in Chinese).
[12] 逯元媛.浅析药用辅料对药品安全性的影响表现[J].科学咨询(科技·管理),2016,17(10):61-62.LU Y Y.A brief analysis of the impact of medical excipients on drug safety [J].Scientific Consultation (Science,Technology,Management),2016,17(10):61-62(in Chinese).
[13] BLOUNT B C,MILGRAM K E,SILVA M J,et al.Quantitative detection of eight phthalate metabolites in human urine using HPLC-APCI-MS/MS[J].Analytical Chemistry,2000,72(17):4127-4134.
[14] 杜庆璋.五类玩具中重金属及邻苯二甲酸酯类(PAEs)的暴露风险评价[D].上海:华东理工大学,2015.DU Q Z.Exposure risk assessment of heavy metals and PAEs in five types of toys [D].Shanghai:East China University of Technology,2015(in Chinese).
[15] FREE C M,JENSEN O P,MASON S A,et al.High-levels of microplastic pollution in a large,remote,mountain lake[J].Marine Pollution Bulletin,2014,85(1):156-163.
[16] AUTA H S,EMENIKE C UFAUZIAH S H.Distribution and importance of microplastics in the marine environment:A review of the sources,fate,effects,and potential solutions[J].Environment International,2017,102:165-176.
[17] JABEEN K,SU L,LI J,et al.Microplastics and mesoplastics in fish from coastal and fresh waters of China[J].Environment Pollution,2017,221:141-149.
[18] BONANNO G,ORLANDO-BONACA M.Ten inconvenient questions about plastics in the sea[J].Environmental Science & Policy,2018,85:146-154.
[19] 刘册家,向兰,杨美华.我国环境中邻苯二甲酸酯类分布状况研究进展[J].中国现代中药,2008,10(3):37-40.LIU C J,XIANG L,YANG M H.Research progress on the distribution of phthalates in China′s environment[J].Modern Chinese Medicine,2008,10(3):37-40(in Chinese).
[20] 王超英,李碧芳,郝金声,等.红枫湖及其污染源中邻苯二甲酸酯类化合物的测定[J].贵州教育学院学报,2006,17(4):42-44.WQANG C Y,LI B F,HAO J S,et al.Determination of phthalate esters in Hongfeng Lake and its pollution source[J].Journal of Guizhou Education Institute (Natural Science),2006,17(4):42-44(in Chinese).
[21] XIONG X,ZHANG K,CHEN X,et al.Sources and distribution of microplastics in China′s largest inland lake - Qinghai Lake[J].Environment Pollution,2018,235:899-906.
[22] DRIS R,GASPERI J,SAAD M,et al.Synthetic fibers in atmospheric fallout:A source of microplastics in the environment?[J].Marine Pollution Bulletin,2016,104(1-2):290-293.
[23] KARLSSON T M,ARNEBORG L,BROSTROM G,et al.The unaccountability case of plastic pellet pollution[J].Marine Pollution Bulletin,2018,129(1):52-60.
[24] LESLIE H A,BRANDSMA S H,VAN VELZEN M J,et al.Microplastics en route:Field measurements in the Dutch river delta and Amsterdam canals,wastewater treatment plants,North Sea sediments and biota[J].Environment International,2017,101:133-142.
[25] GASPERI J,DRIS R,BONIN T,et al.Assessment of floating plastic debris in surface water along the Seine River[J].Environment Pollution,2014,195:163-166.
[26] SRUTHY S,RAMASAMY E V.Microplastic pollution in Vembanad Lake,Kerala,India:The first report of microplastics in lake and estuarine sediments in India[J].Environment Pollution,2017,222:315-322.
[27] GROSS M.Plastic waste is all at sea[J].Current Biology,2013,23(4):135-137.
[28] GANI P,SUNAR N M,MATIAS-PERALTA H,et al.Extraction of hydrocarbons from freshwater green microalgae (Botryococcus sp.) biomass after phycoremediation of domestic wastewater[J].International Journal of Phytoremediation,2017,19(7):679-685.
[29] CHAN H W,CHAN C M,ANG P O,et al.Integrated biosorption and photocatalytic oxidation treatment of di(2-ethylhexyl)phthalate[J].Journal of Applied Phycology,2007,19(6):745-753.
[30] 邱海源,王宪.邻苯二甲酸酯对海洋藻类的致毒效应[J].厦门大学学报(自然版),2005,44(2):294-296.QIU H Y,WANG X.Toxic effects of phthalates on Marine algae [J].Journal of xiamen university (nature),2005,44(2):294-296(in Chinese).
[31] JONSSON S,BAUN A.Toxicity of mono-and diesters of o-phthalic esters to a crustacean,a green alga,and a bacterium[J].Environmental Toxicology & Chemistry,2010,22(12):3037-3043.
[32] GU S,ZHENG H,XU Q,et al.Comparative toxicity of the plasticizer dibutyl phthalate to two freshwater algae[J].Aquatic Toxicology,2017,191:122-130.
[33] 梁智.不同增塑剂对短凯伦藻的生长抑制作用及其机理研究[D].山东:中国海洋大学,2015.LIANG Z.Inhibition effect of different plasticizers on growth and its mechanism of short-kelon algae [D].Shangdong:China Ocean University,2015(in Chinese).
[34] 别聪聪.邻苯二甲酸二丁酯对短裸甲藻的化感抑制机理研究[D].山东:中国海洋大学,2011.BIE C C.Study on the mechanism of dibutyl phthalate inhibiting chlorophyll chemosensitization [D].Shangdong:China Ocean University,2011(in Chinese).
[35] 别聪聪,李锋民,李媛媛,等.邻苯二甲酸二丁酯对短裸甲藻活性氧自由基的影响[J].环境科学,2012,33(2):442-447.BIE C C,LI F M,LI Y Y,et al.Effects of dibutyl phthalate on reactive oxygen free radicals in brassica campestris [J].Environmental Science,2012,33(2):442-447(in Chinese).
[36] HEINDLER F M,ALAJMI F,HUERLIMANN R,et al.Toxic effects of polyethylene terephthalate microparticles and Di(2-ethylhexyl)phthalate on the calanoid copepod,Parvocalanus crassirostris[J].Ecotoxicology Environmental Safety,2017,141:298-305.
[37] 黄国兰,孙红文.邻苯二甲酸二丁酯对大型蚤(Daphniamagna)的毒性作用研究[J].环境化学,1998,17(5):428-433.HUANG G L,SUN H W.Study on the toxicity of dibutyl phthalate on Daphniamagna[J].Environmental Chemistry,1998,17(5):428-433(in Chinese).
[38] LU Y,LIN MAITKEN R J.Exposure of spermatozoa to dibutyl phthalate induces abnormal embryonic development in a marine invertebrate Galeolaria caespitosa (Polychaeta:Serpulidae)[J].Aquatic Toxicology,2017,191:189-200.
[39] 刘伟杰,段舜山.邻苯二甲酸二丁酯对多刺裸腹溞生长繁殖的影响[J].生态科学,2011,30(3):229-235.LIU W J,DUAN S S.Effects of dibutyl phthalate on growth and propagation of daphnia daphnia dorsalis [J].Ecological Science,2011,30(3):229-235(in Chinese).
[40] 王金霞,席贻龙,刘晓波,等.邻苯二甲酸二丁酯对多刺裸腹溞的毒性[J].生态学杂志,2009,28(7):1335-1339.WANG J X,XI Y L,LIU X B,et al.Toxicity of dibutyl phthalate to DPC [J].Journal of Ecology,2009,28(7):1335-1339(in Chinese).
[41] 杜静,于明曦,宋广军,等.基于双壳贝类指示的海洋微塑料污染监测与毒理学研究进展[J].生态学杂志,2018,37(7):2205-2212.DU J,YU M X,SONG G J,et al.Research advances on monitoring and toxicology of microplastic pollution in marine as indicated by bivalves[J].Chinese Journal of Ecology,2018,37(7):2205-2212(in Chinese).
[42] 苏洪波,王兴强,曹梅,等.PAEs对四角蛤蜊毒性和免疫的影响[J].淮海工学院学报.自然科学版,2015,24(4):83-86.SU H B,WANG X Q,CAO M,et al.PAEs on the toxicity and immunity of clams at four corners [J].Journal of Huaihai Institute of Technology.Nature Science Edition,2015,24(4):83-86(in Chinese).
[43] DIGKA N,TSANGARIS C,TORRE M,et al.Microplastics in mussels and fish from the Northern Ionian Sea[J].Marine Pollution Bulletin,2018,135:30-40.
[44] 丁金凤,李景喜,孙承君,等.双壳贝类消化系统中微塑料的分离鉴定及应用研究[J].分析化学,2018,46(5):680-697.DING J F,LI J X,SUN C J,et al.Separation,identification and application of microplastics in digestive system of bivalves[J].Analytical Chemistry,2018,46(5):680-697(in Chinese).
[45] HAN X N,LIU D C.Detection of the toxic substance dibutyl phthalate in Antarctic krill[J].Antarctic Science,2017,29(6):511-516.
[46] 李潇.邻苯二甲酸酯类在养殖鱼类体内含量分析及其胚胎毒性研究[D].广东:暨南大学,2007.LI X.Analysis of phthalates in cultured fish and studies on embryo toxicity [D].Guangdong:Jinan University,2007(in Chinese).
[47] DONG X,QIU X,MENG S,et al.Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels[J].Chemosphere,2018,193:313-320.
[48] SUN G,LIU K.Developmental toxicity and cardiac effects of butyl benzyl phthalate in zebrafish embryos[J].Aquatic Toxicology,2017,192:165-170.
[49] 李文英,熊丽,刘荣,等.邻苯二甲酸二丁酯(DBP)对斑马鱼(Brachydanio rerio)生理生化特性的影响[J].生态毒理学报,2007,2(1):117-122.LI W Y,XIONG L,LIU R,et al.Effects of dibutyl phthalate (DBP) on physiological and biochemical characteristics of zebrafish (Brachydanio rerio)[J].Ecological Toxicology,2007,2 (1):117-122(in Chinese).
[50] ZHU Y,HUA R,ZHOU Y,et al.Chronic exposure to mono-(2-ethylhexyl)-phthalate causes endocrine disruption and reproductive dysfunction in zebrafish[J].Environmental Toxicology & Chemistry,2016,35(8):2117-2124.
[51] 张威振,赖子尼,赵李娜,等.环境中邻苯二甲酸酯类污染物的研究进展[J].中国渔业质量与标准,2014,4(4):13-20.ZHANG W Z,LAI Z N,ZHAO L N,et al.Research progress on phthalate pollutants in the environment [J].Chinese Fishery Quality and Standards,2014,4(4):13-20(in Chinese).
[52] 李学彬,陈莉,吴丹,等.邻苯二甲酸二乙基己酯对金鲫鱼脑组织和肾脏的氧化损伤作用[J].化学与生物工程,2008,25(4):57-59.LI X B,CHEN L,WU D,et al.Effects of diethylhexyl phthalate on oxidative damage of brain tissue and kidney of golden carp [J].Chemical and Biological Engineering,2008,25(4):57-59(in Chinese).
[53] 陈莉,李学彬,杨光涛,等.邻苯二甲酸二乙基己酯(DEHP)对金鲫鱼脑细胞DNA的损伤[J].生态毒理学报,2008,3(2):144-148.CHEN L,LI X B,YANG G T,et al.Damage of diethylhexyl phthalate (DEHP) to brain cell DNA of golden carp [J].Ecological Toxicology,2008,3(2):144-148(in Chinese).
[54] NUGEGODA D,KIBRIA G.Effects of environmental chemicals on fish thyroid function:Implications for fisheries and aquaculture in Australia[J].General and Comparative Endocrinology,2017,244:40-53.
[55] 孙翠竹,李富云,涂海峰,等.邻苯二甲酸酯类对水生食物链的影响研究进展[J].生态毒理学报,2016,11(6):12-24.SUN C Z,LI F Y,TU H F,et al.Research progress on effects of phthalates on aquatic food chain [J].Ecological Toxicology,2016,11(6):12-24(in Chinese).
[56] CZERNYCH R,CHRANIUK M,ZAGO■D■ON P,et al.Characterization of estrogenic and androgenic activity of phthalates by the XenoScreen YES/YAS in vitro assay[J].Environmental Toxicology & Pharmacology,2017,53:95-104.
[57] GAO H T,XU R,CAO W X,et al.Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats[J].Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association,2017,101:94.
[58] 王心.邻苯二甲酸二-(2-乙基己基)酯的雌性生殖毒性研究[D].陕西:第四军医大学,2009.WANG X.Study on female reproductive toxicity of di-(2-ethylhexyl) phthalate [D].Shangxi:Fourth Military Medical University,2009(in Chinese).
[59] GIRIBABU N,REDDY P S.Protection of male reproductive toxicity in rats exposed to di-n-butyl phthalate during embryonic development by testosterone[J].Biomedicine & Pharmacotherapy,2017,87:355-365.
[60] GAO H T,XU R,CAO W X,et al.Effects of six priority controlled phthalate esters with long-term low-dose integrated exposure on male reproductive toxicity in rats[J].Food and Chemical Toxicology,2017,101:94-104.
[61] 柳春红,孙远明,杨艺超,等.邻苯二甲酸酯类增塑剂的污染及暴露评估现状[J].现代食品科技,2012,28(3):339-341.LIU C H,SUN Y M,YANG Y C,et al.Status of pollution and exposure assessment of phthalate plasticizers [J].Modern Food Technology,2012,28(3):339-341(in Chinese).
[62] JIANG L,WANG L,FANG T,et al.Disruption of ergosterol and tryptophan biosynthesis,as well as cell wall integrity pathway and the intracellular pH homeostasis,lead to mono-(2-ethylhexyl)-phthalate toxicity in budding yeast[J].Chemosphere,2018,206:643-654.
[63] KLUWE W M.Overview of phthalate ester pharmacokinetics in mammalian species[J].Environmental Health Perspectives,1982,45(45):3-9.
[64] BUCKNER S L,PRUITT A N,THOMAS C N,et al.Di-N-octylphthalate acts as a proliferative agent in murine cell hepatocytes by regulating the levels of TGF-beta and pro-apoptotic proteins[J].Food and Chemical Toxicology,2018,111:166-175.
[65] FARZANEHFAR V,NADERI N,KOBARFARD F,et al.Determination of dibutyl phthalate neurobehavioral toxicity in mice[J].Food and Chemical Toxicology,2016,94:221-226.
[66] TAN S,WANG D,CHI Z,et al.Study on the interaction between typical phthalic acid esters (PAEs) and human haemoglobin (hHb) by molecular docking[J].Environmental Toxicology and Pharmacology,2017,53:206-211.
[67] JUREWICZ J,HANKE W.Exposure to phthalates:reproductive outcome and children health.A review of epidemiological studies[J].International Journal of Occupational Medicine and Environmental Health,2011,24(2):115-141.
[68] SWAN S H,MAIN K M,LIU F,et al.Decrease in anogenital distance among male infants with prenatal phthalate exposure[J].Environmental Health Perspectives,2005,113(8):1056-1061.
[69] ZHANG J J,SHU W Q.Progress in phthalate ester toxicity in the female reproductive system[J].Journal of Hygiene Research,2005,34(4):496-498.
[70] SINGH N,DALAL VKUMAR P.Structure based mimicking of Phthalic acid esters (PAEs) and inhibition of hACMSD,an important enzyme of the tryptophan kynurenine metabolism pathway[J].International Journal of Biological Macromolecules,2018,108:214-224.
[71] DEL BUBBA M,ANCILLOTTI C,CHECCHINI L,et al.Determination of phthalate diesters and monoesters in human milk and infant formula by fat extraction,size-exclusion chromatography clean-up and gas chromatography-mass spectrometry detection[J].Journal of Pharmaceutical and Biomedical Analysis,2018,148:6-16.
[72] 张蕴晖,陈秉衡,郑力行,等.人体生物样品中邻苯二甲酸酯类的含量[J].中华预防医学杂志,2003,37(6):429-434.ZHANG Y H,CHEN B H,ZHENG L X,et al.Contents of phthalates in human biological samples [J].Chinese journal of preventive medicine,2003,37(6):429-434(in Chinese).
[73] 何雪峰.测定水中邻苯二甲酸酯类化合物液液萃取法与固相萃取法的选择[J].绿色科技,2017,2(6):9-11.HE X F.Determination of the choice of liquid extraction method and solid phase extraction method for phthalates in water [J].Green Technology,2017,2(6):9-11(in Chinese).
[74] 刘铭雪,丁爱中,张波涛,等.水中邻苯二甲酸酯的分析检测[J].工业水处理,2015,35(10):12-16.LIU M X,DING A Z,ZHANG B T,et al.Analysis and detection of phthalate in water [J].Industrial Water Treatment,2015,35(10):12-16(in Chinese).
[75] FERNANDEZ-GONZALEZ V,MOSCOSO-PEREZ C,MUNIATEGUI-LORENZO S,et al.Reliable,rapid and simple method for the analysis of phthalates in sediments by ultrasonic solvent extraction followed by head space-solid phase microextraction gas chromatography mass spectrometry determination[J].Talanta,2017,162:648-653.
[76] 马燕玲,陈令新,丁养军,等.超声辅助分散液液微萃取-高效液相色谱测定水样中的4种邻苯二甲酸酯类增塑剂[J].色谱,2013,31(2):155-161.MA Y L,CHEN L X,DING Y J,et al.Determination of four phthalate plasticizers in water samples by ultrasound-assisted dispersive liquid microextraction - HPLC[J].Chromatography,2013,31 (2):155-161(in Chinese).
[77] 陈飞.分散液液微萃取-气相色谱法测定海水中的邻苯二甲酸酯[J].福建分析测试,2014,23(3):33-37.CHEN F.Determination of phthalates in seawater by dispersive liquid microextraction with gas chromatography [J].Fujian Analytical Test,2014,23(3):33-37(in Chinese).
[78] WANG J,HUANG S,WANG P,et al.Method development for the analysis of phthalate esters in tea beverages by ionic liquid hollow fibre liquid-phase microextraction and liquid chromatographic detection[J].Food Control,2016,67:278-284.
[79] SALAZAR-BELTRAN D,HINOJOSA-REYES L,RUIZ-RUIZ E,et al.Determination of phthalates in bottled water by automated on-line solid phase extraction coupled to liquid chromatography with UV detection[J].Talanta,2017,168:291-297.
[80] 胡锋,刘功斌,袁新龙.固相萃取—高效液相色谱法测定水中阿特拉津和2种邻苯二甲酸酯[J].干旱环境监测,2015,29(2):61-65.HU F,LIU G B,YUAN X L.Determination of atrazine and two phthalates in water by solid-phase extraction (HPLC)[J].Drought Environment Monitoring,2015,29(2):61-65(in Chinese).
[81] LIANG J,NING X A,KONG M,et al.Elimination and ecotoxicity evaluation of phthalic acid esters from textile-dyeing wastewater[J].Environ Pollut,2017,231(1):115-122.
[82] 沈斐,苏晓燕,李睿,等.固相萃取-气相色谱法测定水环境中邻苯二甲酸酯[J].中国环境监测,2014,30(1):150-153.SHEN F,SU X Y,LI R,et al.Determination of phthalates in water environment by solid-phase extraction and gas chromatography [J].China Environmental Monitoring,2014,30(1):150-153(in Chinese).
[83] ARTHUR C L,PAWLISZYN J.Solid phase microextraction with thermal desorption using fused silica optical fibers[J].Analytical Chemistry,1990,62(19):2145-2148.
[84] BANDFORUZI S R,HADJMOHAMMADI M R.Application of non-ionic surfactant as a developed method for the enhancement of two-phase solvent bar microextraction for the simultaneous determination of three phthalate esters from water samples[J].Journal of Chromatography A,2018,1561:39-47.
[85] FERN n-G l V,MOSCOSO-P 瘙嚍REZ C,MUNIATEGUI-LORENZO S,et al.Reliable,rapid and simple method for the analysis of phthalates in sediments by ultrasonic solvent extraction followed by head space-solid phase microextraction gas chromatography mass spectrometry determination[J].Talanta,2017,162:648-653.
[86] 张泽明,张洪海,李建龙,等.固相微萃取-气相色谱-质谱联用测定海水与沉积物中邻苯二甲酸酯类污染物[J].分析化学,2017,45(3):348-356.ZHANG Z M,ZHANG H H,LI J L,et al.Determination of phthalates in seawater and sediments by solid-phase microextraction - gas chromatography - mass spectrometry[J].Analytical Chemistry,2017,45(3):348-356(in Chinese).
[87] 刘芃岩,高丽,申杰,等.固相微萃取-气相色谱法测定白洋淀水样中的邻苯二甲酸酯类化合物[J].色谱,2010,28(5):517-520.LIU P Y,GAO L,SHEN J,et al.Determination of phthalates in baiyangdian water samples by solid-phase microextraction and gas chromatography [J].Chromatography,2010,28(5):517-520(in Chinese).
[88] JORNET-MARTINEZ N,MUNOZ-ORTUNO M,MOLINER-MARTINEZ Y,et al.On-line in-tube solid phase microextraction-capillary liquid chromatography method for monitoring degradation products of di-(2-ethylhexyl) phthalate in waters[J].Journal of Chromatography A,2014,1347:157-160.
[89] 马鲲鹏,李琰,王冬究,等.水中邻苯二甲酸酯类化合物的固相膜萃取-气相质谱测定法[J].职业与健康,2015,31(13):1771-1773.MA K P,LI Y,WANG D J,et al.Determination of phthalates in water by solid-phase membrane extraction and gas phase mass spectrometry[J].Occupational and Health,2015,31(13):1771-1773(in Chinese).
[90] SI Q,LI F,GAO C,et al.Detection of phthalate esters in seawater by stir bar sorptive extraction and gas chromatography-mass spectrometry[J].Marine Pollution Bulletin,2016,108(1-2):163-170.
[91] MESDAGHINIA A,AZARI A,NODEHI R N,et al.Removal of phthalate esters (PAEs) by zeolite/Fe3O4:Investigation on the magnetic adsorption separation,catalytic degradation and toxicity bioassay[J].Journal of Molecular Liquids,2017,233:378-390.
[92] TANG M,WU Y,DENG D,et al.Development of an optical fiber immunosensor for the rapid and sensitive detection of phthalate esters[J].Sensors and Actuators B:Chemical,2018,258:304-312.
[93] YAN Z,HE M,CHEN B,et al.Magnetic covalent triazine framework for rapid extraction of phthalate esters in plastic packaging materials followed by gas chromatography-flame ionization detection[J].Journal of Chromatography A,2017,1525:32-41.
[94] LIANG Y R,ZHANG Z M,LIU Z J,et al.A highly sensitive signal-amplified gold nanoparticle-based electrochemical immunosensor for dibutyl phthalate detection[J].Biosens Bioelectron,2017,91:199-202.
[95] XU W,ZHANG X,HUANG W,et al.Synthesis of surface molecular imprinted polymers based on carboxyl-modified silica nanoparticles with the selective detection of dibutyl phthalate from tap water samples[J].Applied Surface Science,2017,426:1075-1083.
[96] 李健华,廖林波.浊点萃取-气相色谱法测定水中邻苯二甲酸酯类化合物[J].海峡药学,2016,28(1):45-48.LI J H,LIAO J B.Determination of phthalates in water by turbidimetric extraction and gas chromatography[J].Strait Pharmacology,2016,28(1):45-48(in Chinese).
[97] 沈斐,苏晓燕,李睿,等.固相萃取-气相色谱法测定水环境中邻苯二甲酸酯[J].中国环境监测,2014,30(1):150-153.SHEN F,SUN X Y,LI R,et al.Determination of phthalate esters in water by solid-phase extraction and gaschromatography[J].Environmental Monitoring in China,2014,30(1):150-153(in Chinese).
[98] 石凤琼,柯常亮,林钦,等.气相色谱-质谱法测定水产品中15种邻苯二甲酸酯类塑化剂的残留量[J].分析测试学报,2013,32(8):915-922.SHI F Q,KE C L,LIN Q,et al.Determination of residues of 15 phthalates plasticizers in aquatic products by gas chromatography-mass spectrometry [J].Journal of Analysis and Testing,2013,32 (8):915-922(in Chinese).
[99] 张泽明,张洪海,李建龙,等.固相微萃取-气相色谱-质谱联用测定海水与沉积物中邻苯二甲酸酯类污染物[J].分析化学,2017,45(03):348-356.ZHANG Z-M,ZHANG H-H,LI J-L,et al.Determination of phthalic acid esters in seawater and sediment by solid-phase microextraction and gas chromatography-mass spectrometry[J].Chinese Journal of Analytical Chemistry,2017,45(3):348-356.
[100] OTERO P,SAHA S K,MOANE S,et al.Improved method for rapid detection of phthalates in bottled water by gas chromatography-mass spectrometry[J].Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences,2015,997:229-235.
[101] 李玉玉,凌云,郭浩楠,等.气相色谱-质谱法测定水产品中24种邻苯二甲酸酯类化合物[J].分析测试学报,2013,32(4):408-413.LI Y Y,LING X,GUO H N,et al.Determination of 24 phthalates in aquatic products by gas chromatography-mass spectrometry [J].Journal of Analysis and Testing,2013,32(4):408-413(in Chinese).
[102] LEBEDEV A T,POLYAKOVA O V,MAZUR D M,et al.Detection of semi-volatile compounds in cloud waters by GCxGC-TOF-MS.Evidence of phenols and phthalates as priority pollutants[J].Environmental Pollution,2018,241:616-625.
[103] TARAFDAR A,SARKAR T K,CHAKRABORTY S,et al.Biofilm development of Bacillus thuringiensis on MWCNT buckypaper:Adsorption-synergic biodegradation of phenanthrene[J].Ecotoxicology and Environmental Safety,2018,157:327-334.
[104] GOMARA B,LEBRON-AGUILAR R,GONZALEZ M J,et al.Insight into the retention processes of phthalate metabolites on different liquid chromatography stationary phases for the development of improved separation methods[J].Journal of Chromatography A,2015,1423:86-95.
[105] 魏丽琼,呼世斌,刘书慧,等.QuEChERS-高效液相色谱法测定土壤中邻苯二甲酸酯[J].环境工程,2016,34(5):148-151.WEI L Q,HU S B,LIU S H,et al.Determination of phthalates in soil by quechers-high performance liquid chromatography[J].Environmental Engineering,2016,34(5):148-151(in Chinese).
[106] 曹攽,李云木子,马军,等.超声波萃取-高效液相色谱法测定土壤中邻苯二甲酸酯[J].岩矿测试,2011,30(2):178-181.CAO Y,LI Y M Z,MA JUN,et al.Determination of phthalates in soil by ultrasonic extraction-high performance liquid chromatography[J].Rock and Mineral Exploration,2011,30(2):178-181(in Chinese).
[107] VIDAL R B P,IBANEZ G AESCANDAR G M.A green method for the quantification of plastics-derived endocrine disruptors in beverages by chemometrics-assisted liquid chromatography with simultaneous diode array and fluorescent detection[J].Talanta,2016,159:336-343.
[108] 刘超.液质联用技术测定邻苯二甲酸酯类及酚类环境激素的研究[D].江西:南昌大学,2007.LIU C.A study on the determination of phthalic acid esters and phenol environmental hormones by combined liquid and mass technique [D].Jiangxi:Nanchang University,2007(in Chinese).
[109] RAMESH KUMAR A,SIVAPERUMAL P.Analytical methods for the determination of biomarkers of exposure to phthalates in human urine samples[J].TrAC Trends in Analytical Chemistry,2016,75:151-161.
[110] 王风红,芦春梅,胡婷婷,等.高效液相色谱-串联质谱法测定化妆品中的邻苯二甲酸酯[J].化学试剂,2015,37(2):135-138.WANG F H,LU C M,HU T T,et al.Determination of phthalate esters in cosmetics by high performance liquid chromatography-tandem mass spectrometry[J].Chemical Reagents,2015,37 (2):135-138(in Chinese).
[111] ZHOU Z,LI T,XU W,et al.Synthesis and characterization of fluorescence molecularly imprinted polymers as sensor for highly sensitive detection of dibutyl phthalate from tap water samples[J].Sensors and Actuators B:Chemical,2017,240:1114-1122.
[112] ZHU F,MAO CDU D.Time-resolved immunoassay based on magnetic particles for the detection of diethyl phthalate in environmental water samples[J].Science of Total Environment,2017,601-602:723-731.
[113] HE F,TIAN Y,XU Z,et al.Development of an immunochromatographic assay as a screen for detection of total phthalate acid esters in cooking oil[J].Journal of Toxicology and Environmental Health,PartA,2018,81(4):80-88.
[114] ZHU N,ZOU Y,HUANG M,et al.A sensitive,colorimetric immunosensor based on Cu-MOFs and HRP for detection of dibutyl phthalate in environmental and food samples[J].Talanta,2018,186:104-109.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |