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依达拉奉对急性脑出血患者自由基含量的影响及临床疗效分析
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摘要
目的:探析依达拉奉对急性脑出血患者自由基含量的影响及临床疗效。方法:抽选2013年1月至2015年10月我院治疗的60例急性脑出血患者,随机分为两组实施探究实验。结果:治疗后1周与治疗后2周,两组患者的ADL、ESS评分存在显著差异性(P<0.05)。治疗后,观察组患者的SOD、IL-6分别是(30.7±9.5)U/ml、(8.43±1.92)pg/ml,对照组分别是(25.6±9.7)U/ml、(12.24±1.42)pg/ml,存在显著差异性(P<0.05)。结论:依达拉奉治疗急性脑出血患者的临床疗效较为理想,降低自由基的浓度。
Objective: To explore the impact of the free radical content of edaravone in patients with acute cerebral hemorrhage and its clinical efficacy. Methods: patients were selected fromJanuary 2013 to October 2015, 60 cases of acute cerebral hemorrhage treated in our hospital, were randomly divided into two groups of experimental inquiry. Results: after 1 weeks of treatment and 2 weeks after treatment, there were significant differences in ESS and ADL scores between the two groups(P < 0.05). After treatment, the IL-6 and pg/ml of the observation group were(30.7 + 9.5) U/ml,(8.43 1.92) SOD, the control group were(25.6 + 9.7) U/ml,(12.24 1.42) pg/ml, there was significant difference(P < 0.05). Conclusion: Edaravone in treatment of acute cerebral hemorrhage patient'sclinical curative effect is ideal, decreased the concentration of free radicals.
引文
[1]李玲,陈康宁.脑出血后继发脑损伤机制的研究进展[J].第三军医大学学报,2005,27(19):1992-1994.
    [2]李春明.依达拉奉治疗脑出血32例疗效观察[J].广西医学,2009,31(1):101-102.
    [3]白爱国.依达拉奉对急性脑出血患者血清NSE、IL-6、TNF-α及神经功能的影响[J].山东医药,2011,51(27):37-38.
    [4]庄绪娟,李春华,江毅等.依达拉奉对急性脑出血患者神经功能恢复的效果研究[J].临床神经病学杂志,2011,24(5):399-399.
    [5]王兴池,康继双.依达拉奉对急性脑出血患者血清白细胞介素-6、肿瘤坏死因子-α水平及神经功能的影响[J].中国基层医药,2011,18(10):1343-1344.

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