综合护理干预在实施黄体期卵巢刺激方案卵巢功能下降患者中的应用效果
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摘要
目的探讨综合护理干预对实施黄体期卵巢刺激方案患者卵巢功能下降的应用效果。方法选择2016年2月～2018年2月在我院接受黄体期卵巢刺激方案的120例卵巢功能下降患者作为研究对象,按照随机数字表法分为观察组和对照组,每组各60例。对照组给予一般护理干预,观察组给综合护理干预。比较两组促性腺激素(Gn)使用时间、使用量及绒毛膜促性腺激素(HCG)注射日雌二醇(E_2)水平、获卵数、可利用胚胎数情况,临床妊娠率、早期流产率、周期取消率。结果观察组Gn使用时间长于对照组,Gn使用量和HCG注射日E_2水平高于对照组,获卵个数和可利用胚胎数多于对照组,临床妊娠率高于对照组,差异均有统计学意义(P<0.05)。结论综合护理干预可显著提高接受黄体期卵巢刺激方案治疗的卵巢功能下降患者HCG注射日E_2水平、获卵数、可利用胚胎数,改善临床妊娠率。
Objective To explore the effect of comprehensive nursing intervention on ovarian dysfunction in patients undergoing luteal phase ovarian stimulation program. Methods From February 2016 to February 2018, 120 patients with ovarian dysfunction who received luteal phase ovarian stimulation program in our hospital were selected as subjects for observation. According to the random number table method, they were divided into observation group and control group, 60 cases in each group. The control group was given general nursing intervention, while the observation group was given comprehensive nursing intervention on the basis of general nursing. The time and amount of gonadotrophic hormone(Gn) use, the estradiol level on the day of(HCG) injection, the number of eggs harvested, the number of embryos available, the clinical pregnancy rate, the early abortion rate and the cancellation rate of cycles were compared between the two groups. Results The Gn use time of the observation group was longer than that of the control group, Gn use and estradiol level on the day of HCG injection were higher than those in the control group, the number of eggs and available embryos was more than that of the control group, the clinical pregnancy rate was higher than that of the control group, the differences were statistically significant(P<0.05). Conclusion Comprehensive nursing intervention can significantly improve the level of estradiol injection daily, the number of eggs obtained, the number of embryos available, and the clinical pregnancy rate in patients with decreased ovarian function treated with luteal stage ovarian stimulation.
Objective To explore the effect of comprehensive nursing intervention on ovarian dysfunction in patients undergoing luteal phase ovarian stimulation program. Methods From February 2016 to February 2018, 120 patients with ovarian dysfunction who received luteal phase ovarian stimulation program in our hospital were selected as subjects for observation. According to the random number table method, they were divided into observation group and control group, 60 cases in each group. The control group was given general nursing intervention, while the observation group was given comprehensive nursing intervention on the basis of general nursing. The time and amount of gonadotrophic hormone(Gn) use, the estradiol level on the day of(HCG) injection, the number of eggs harvested, the number of embryos available, the clinical pregnancy rate, the early abortion rate and the cancellation rate of cycles were compared between the two groups. Results The Gn use time of the observation group was longer than that of the control group, Gn use and estradiol level on the day of HCG injection were higher than those in the control group, the number of eggs and available embryos was more than that of the control group, the clinical pregnancy rate was higher than that of the control group, the differences were statistically significant(P<0.05). Conclusion Comprehensive nursing intervention can significantly improve the level of estradiol injection daily, the number of eggs obtained, the number of embryos available, and the clinical pregnancy rate in patients with decreased ovarian function treated with luteal stage ovarian stimulation.
引文
[1]梁见弟,张昭.微刺激方案与黄体期促排卵方案在卵巢储备功能低下患者体外受精-胚胎移植周期中的应用效果对比[J].中国当代医药,2018,25(26):94-96.
[2]刘晓娉,王波,李婷婷,等.不同刺激方案对卵巢低反应患者体外受精结局影响的比较[J].中山大学学报(医学科学版),2018,39(6):860-865.
[3]邓媛.综合护理干预在重度卵巢过度刺激综合征病人中的应用[J].全科护理,2018,16(2):198-199.
[4]马红霞,邢金玲.中医综合护理干预对卵巢早衰不孕患者的临床效果[J].中国当代医药,2018,25(26):206-208.
[5]戚阳,柴德春.女性不孕不育患者抑郁影响因素分析与护理干预对策[J].护理实践与研究,2018,15(22):9-12.
[6]王明连,闫晓燕.护理干预对肥胖型多囊卵巢综合征不孕患者的影响[J].齐鲁护理杂志,2018,24(6):72-74.
[7]章昉,茅丽琴,陆爱芬,等.体外受精-胚胎移植后并发卵巢扭转12例的原因分析及预防对策[J].护理与康复,2017,16(3):255-257.
[8]刘小菊,全晓广,聂莹,等.中医体质辨识视角下的个体化健康指导对高龄孕前妇女卵巢储备功能的影响[J].护理实践与研究,2017,14(11):133-134.
[9]夏弘,姚辰希,张静,等.卵巢低反应妇女助孕治疗后临床结局的影响因素分析[J].中国计划生育学杂志,2018,26(3):211-214.
[10]刘敏,张建梅,梁莹,等.卵巢低反应患者不同促排卵方案应用效果比较[J].生殖医学杂志,2018,27(9):898-903.
[11]王靖,邢琼,王超,等.3种不同促排卵方案在高龄不孕患者IVF/ICSI-ET中的临床应用分析[J].安徽医科大学学报,2018,53(7):1080-1084.
[12]闫春秀.促排卵治疗联合护理干预在肥胖型多囊卵巢综合征不孕患者中的应用效果[J].临床合理用药杂志,2018,11(15):157-159.
[13]王娟.中医综合护理干预对卵巢早衰不孕患者的效果分析[J].实用妇科内分泌电子杂志,2018,5(30):102-103.
[14]张晴,王锐娜,曹瑜青.护理干预对肥胖型多囊卵巢综合征不孕患者的影响[J].实用妇科内分泌电子杂志,2018,5(11):68-69.
[15]胡瑞芳,冀丽帆,陈丽萍,等.患者自助使用果纳芬笔的护理宣教对策及安全性分析[J].中国医药科学,2017,7(18):135-137.
[16]黄洁,蔡令波,刁飞扬,等.应用全面质量管理体系运转法降低辅助生殖技术刺激周期中重度卵巢过度刺激综合征发生率[J].生殖与避孕,2018,38(8):616-620.
[17]王娜娜,万凌屹.综合护理干预对多囊卵巢综合征不孕患者抑郁心理及生活质量的影响[J].中国现代医生,2018,56(4):158-161.
[18]彭玲,储亚平,魏兆莲,等.40岁以上高龄妇女获卵数对体外受精-胚胎移植助孕结局的影响[J].安徽医科大学学报,2017,52(1):105-108.
[2]刘晓娉,王波,李婷婷,等.不同刺激方案对卵巢低反应患者体外受精结局影响的比较[J].中山大学学报(医学科学版),2018,39(6):860-865.
[3]邓媛.综合护理干预在重度卵巢过度刺激综合征病人中的应用[J].全科护理,2018,16(2):198-199.
[4]马红霞,邢金玲.中医综合护理干预对卵巢早衰不孕患者的临床效果[J].中国当代医药,2018,25(26):206-208.
[5]戚阳,柴德春.女性不孕不育患者抑郁影响因素分析与护理干预对策[J].护理实践与研究,2018,15(22):9-12.
[6]王明连,闫晓燕.护理干预对肥胖型多囊卵巢综合征不孕患者的影响[J].齐鲁护理杂志,2018,24(6):72-74.
[7]章昉,茅丽琴,陆爱芬,等.体外受精-胚胎移植后并发卵巢扭转12例的原因分析及预防对策[J].护理与康复,2017,16(3):255-257.
[8]刘小菊,全晓广,聂莹,等.中医体质辨识视角下的个体化健康指导对高龄孕前妇女卵巢储备功能的影响[J].护理实践与研究,2017,14(11):133-134.
[9]夏弘,姚辰希,张静,等.卵巢低反应妇女助孕治疗后临床结局的影响因素分析[J].中国计划生育学杂志,2018,26(3):211-214.
[10]刘敏,张建梅,梁莹,等.卵巢低反应患者不同促排卵方案应用效果比较[J].生殖医学杂志,2018,27(9):898-903.
[11]王靖,邢琼,王超,等.3种不同促排卵方案在高龄不孕患者IVF/ICSI-ET中的临床应用分析[J].安徽医科大学学报,2018,53(7):1080-1084.
[12]闫春秀.促排卵治疗联合护理干预在肥胖型多囊卵巢综合征不孕患者中的应用效果[J].临床合理用药杂志,2018,11(15):157-159.
[13]王娟.中医综合护理干预对卵巢早衰不孕患者的效果分析[J].实用妇科内分泌电子杂志,2018,5(30):102-103.
[14]张晴,王锐娜,曹瑜青.护理干预对肥胖型多囊卵巢综合征不孕患者的影响[J].实用妇科内分泌电子杂志,2018,5(11):68-69.
[15]胡瑞芳,冀丽帆,陈丽萍,等.患者自助使用果纳芬笔的护理宣教对策及安全性分析[J].中国医药科学,2017,7(18):135-137.
[16]黄洁,蔡令波,刁飞扬,等.应用全面质量管理体系运转法降低辅助生殖技术刺激周期中重度卵巢过度刺激综合征发生率[J].生殖与避孕,2018,38(8):616-620.
[17]王娜娜,万凌屹.综合护理干预对多囊卵巢综合征不孕患者抑郁心理及生活质量的影响[J].中国现代医生,2018,56(4):158-161.
[18]彭玲,储亚平,魏兆莲,等.40岁以上高龄妇女获卵数对体外受精-胚胎移植助孕结局的影响[J].安徽医科大学学报,2017,52(1):105-108.
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