妇科内分泌症患者性激素类药物的合理使用探讨

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英文篇名：Discussion on Rational Use of Sex Hormone Drugs in Patients with Gynecological Endocrine 作者：李玉秀 英文作者：LI Yu-xiu;Juye County Maternal and Child Health Family Planning Service Center; 关键词：妇科内分泌症 ; 性激素类药物 ; 合理使用情况 英文关键词：Gynecological endocrine disease;;Sex hormone drugs;;Reasonable use situation 中文刊名：XTYX 英文刊名：Systems Medicine 机构：巨野县妇幼保健计划生育服务中心; 出版日期：2019-02-05 出版单位：系统医学 年：2019 期：v.4;No.63 语种：中文; 页：XTYX201903004 页数：3 CN：03 ISSN：10-1369/R 分类号：12-14

摘要

目的针对妇科内分泌症患者使用性激素类药物治疗的情况进行调查,分析药物使用期间的合理性。方法纳入2017年1—12月期间该院收治的80例妇科内分泌症患者进行回顾性研究,查病例号按照奇数偶数将其分为对照组和实验组,每组纳入40例。合理采用激素类药物治疗即为实验组,未合理采用激素类药物治疗治疗即为对照组,详解两组的治疗效果及用药错误率。结果在临床治疗总有效率方面,对照组为75.00%(30/40),实验组为95.00%(38/40),实验组要明显高于对照组,差异有统计学意义(χ~2=6.274 5,P<0.05);对照组的8例不合理用药中,私下用药1例,剂量错误1例,遗忘2例,害怕"激素"1例,不良反应1例,药理作用理解错误2例;实验组2例不合理用药中,私下用药1例,药理作用理解错误1例,实验组患者的用药错误合计率5.00%对比对照组20.00%明显更低,差异有统计学意义(χ~2=4.114 3,P<0.05)。结论妇科内分泌症患者性激素类药物的使用过程中,剂量错误、药理作用理解错误、私下用药等不合理现象,导致治疗的效果大受影响,针对存在的不合理现象,积极地采取相应措施加以干预,可以降低不合理用药的发生率,提升治疗的效果,促进患者的健康恢复。
        Objective To investigate the rational use of sex hormones in patients with gynecological endocrinology and to analyze the rationality of drug use. Methods A retrospective study was performed on 80 patients with gynecological endocrinology admitted to our hospital from January December 2017. The case numbers were divided into control group and experimental group according to odd even numbers, and 40 cases were included in each group. The rational use of hormonal drugs in the experimental group, and the treatment with hormonal drugs is not used as the control group, and the treatment effect and drug error rate of the two groups were explained in detail. Results In the total effective rate of clinical treatment, the control group was 75.00%(30/40), and the experimental group was 95.00%(38/40). The experimental group was significantly higher than the control group, and the difference was statistically significant(χ~2=6.2745,P <0.05); 8 cases of irrational medication in the control group, 1 case of private medication, 1 case of wrong dose, 2 cases of forgetting, 1 case of "hormone", 1 case of adverse reaction, 2 cases of misunderstanding of pharmacological effects; experimental group of 2 cases of irrational use, 1 case was treated privately, 1 case was misunderstood, and the error rate of drug use in the experimental group was 5.00% compared with 20.00% in the control group. The difference was statistically significant(χ~2=4.114 3, P<0.05). Conclusion During the use of sex hormone drugs in patients with gynecological endocrinology, the irrational effects of dose error, misunderstanding of pharmacological effects, private medication, etc., have greatly affected the treatment effect, actively take corresponding measures to address the irrational phenomenon. Intervention can reduce the incidence of irrational use of drugs, improve the effectiveness of treatment,and promote the recovery of patients' health.

引文

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