2004-2017年武汉市病毒性肝炎流行病学特征分析
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摘要
目的分析武汉市病毒性肝炎流行病学特征及规律,为制定防控措施提供依据。方法运用描述性流行病学方法对2004-2017年武汉市病毒性肝炎疫情数据进行分析,不同地区、性别等分布差异采用χ~2检验,探讨影响武汉市病毒性肝炎流行病学特征的相关因素。结果 2004-2017年武汉市累计报告病毒性肝炎病例数124 415例,年均发病率98.76/10万,总体呈下降趋势。乙肝报告病例数最多,占71.68%,其次为丙肝,占14.70%。年均报告发病率前三位的地区均为中心城区(χ~2=9 510.51,P<0.05),男性发病率(年平均发病率130.52/10万)高于女性(年平均发病率65.08/10万)(χ~2=13 662.96,P<0.05)。乙肝发病率最高峰在50～岁年龄组,甲肝、乙肝、丙肝、戊肝及未分型肝炎的报告发病率均随年龄增加而增加(甲肝:χ~2=583.05,P<0.05;乙肝:χ~2=12 774.17,P<0.05;丙肝:χ~2=10 076.97,P<0.05;戊肝:χ~2=4 350.77,P<0.05;未分型肝炎:χ~2=1 548.14,P<0.05)。职业以家政、家务及待业、离退休人员及农民为主。结论武汉市病毒性肝炎的报告发病率虽然呈下降趋势,但在传染病报告发病中仍占重要位置,其防治应以乙肝为重点。在做好免疫预防工作的基础上,应针对性地加强重点地区重点人群的防控工作。
Objective To understand the epidemiological features of viral hepatitis from 2004 to 2017in Wuhan,and to provide scientific evidences for disease control and prevention. Methods Descriptive epidemiological analysis method was used to analyze the epidemic characteristics of viral hepatitis,chi-square test was adopted to analyze the differences of disease geographical and gender distributions. Results A total of124 415 viral hepatitis cases were reported from 2004 to 2017in Wuhan with the annual incidence of 98.76/100 000.Majority of cases were hepatitis B,accounting for 71.68%,followed by hepatitis C,accounting for14.70%.The top three areas with high incidence were all located in central urban(χ2=9 510.51,P<0.05).There were more male cases than females(χ2=13 662.96,P<0.05).The highest incidence of hepatitis B was among individuals in 50-60 age group,while the incidences of hepatitis A,C,E,and unclassified hepatitis were all increasing with age(P<0.05).Most cases were unemployed persons,retirees or famers. Conclusions Although the reported incidence of viral hepatitis in Wuhan is decreasing,viral hepatitis cases are still common in the region,especially those with hepatitis B.On the basis of immune prevention,prevention and control of key population in key areas should be strenghtened.
Objective To understand the epidemiological features of viral hepatitis from 2004 to 2017in Wuhan,and to provide scientific evidences for disease control and prevention. Methods Descriptive epidemiological analysis method was used to analyze the epidemic characteristics of viral hepatitis,chi-square test was adopted to analyze the differences of disease geographical and gender distributions. Results A total of124 415 viral hepatitis cases were reported from 2004 to 2017in Wuhan with the annual incidence of 98.76/100 000.Majority of cases were hepatitis B,accounting for 71.68%,followed by hepatitis C,accounting for14.70%.The top three areas with high incidence were all located in central urban(χ2=9 510.51,P<0.05).There were more male cases than females(χ2=13 662.96,P<0.05).The highest incidence of hepatitis B was among individuals in 50-60 age group,while the incidences of hepatitis A,C,E,and unclassified hepatitis were all increasing with age(P<0.05).Most cases were unemployed persons,retirees or famers. Conclusions Although the reported incidence of viral hepatitis in Wuhan is decreasing,viral hepatitis cases are still common in the region,especially those with hepatitis B.On the basis of immune prevention,prevention and control of key population in key areas should be strenghtened.
引文
[1]孔毅,许琳,康文玉,等.云南省1959-2014年病毒性肝炎流行特征分析[J].中国卫生统计,2016,33(4):657-659.
[2] Park H,Jeong D,Nguyen P,et al.Economic and clinical burden of viral hepatitis in California:A population-based study with longitudinal analysis[J].PLoS One,2018,13(4):e0196452.
[3] Ma W,Soliman AS,Anwar WA,et al.Forecasted impacts of a sofosbuvir-based national hepatitis C treatment programme on Egypt′s hepatocellular cancer epidemic:simulation of alternatives[J].BMJ Glob Health,2018,3(2):e000572.
[4]国家卫生计生委办公厅关于印发传染病信息报告管理规范(2015年版)的通知(国卫办疾控发[2015]53号)[J].中华人民共和国国家卫生和计划生育委员会公报,2015(10):36-42.
[5]李扬,耿爱生,汪心海,等.中国病毒性肝炎流行状况GIS空间分析[J].中国卫生统计,2016,33(2):235-238.
[6] Zhu B,Liu J,Fu Y,et al.Spatio-Temporal Epidemiology of Viral Hepatitis in China(2003-2015):Implications for Prevention and Control Policies[J].Intl J Environ Res Public Health,2018,15(4):661.
[7]孙虹.2014年度全国法定传染病疫情情况[J].吉林医学信息,2015(2):26-27.
[8]张敏娜,袁月,貌盼勇,等.中国2004-2013年病毒性肝炎发病与死亡趋势分析[J].中华流行病学杂志,2015,36(2):144-147.
[9]徐爱强,张丽.中国病毒性肝炎血清流行病学调查的回顾与意义[J].中华预防医学杂志,2017,51(6):457-461.
[10]张万军,张瑾,袁兆虎,等.江苏省镇江市2004-2015年病毒性肝炎流行特征分析[J].中国卫生统计,2017,34(2):240-242.
[11]刘义文,蒲中枢,吉兆华,等.甘肃省武威市2005-2013年病毒性肝炎发病趋势分析[J].中国卫生统计,2016,33(1):148-149.
[12]洪佳冬,康燕,李建杰.广州市荔湾区2004-2013年病毒性肝炎流行病学特征分析[J].华南预防医学,2015,41(3):266-269.
[13]韩喜荣.北京市海淀区病毒性肝炎流行病学特征[J].中国卫生检验杂志,2014,24(16):2425-2427.
[14] Lee SW,Lee TY,Yang SS,et al.Prevalence of hepatitis B reactivation among chinese individuals with chronic hepatitis c treated with Pan-Oral direct-acting antivirals[J].Gastroenterol Res,2018,11(2):124-129.
[15]武荣,杜秀芳,王坤,等.临汾市尧都区2010-2015年病毒性肝炎流行病学特征分析[J].中国老年学杂志,2017,37(21):5446-5448.
[16]胡海洋,傅更锋,卢静,等.江苏省2005-2012年丙型肝炎流行特征分析[J].中华疾病控制杂志,2015,19(4):393-395.
[17] Zou X,Chow EP,Zhao P,et al.Rural-to-urban migrants are at high risk of sexually transmitted and viral hepatitis infections in China:a systematic review and meta-analysis[J].BMC Infect Dis,2014,14:490.
[18] Li L,Lan X.Association between hepatitis B virus/hepatitis C virus infection and primary hepatocellular carcinoma risk:A meta-analysis based on Chinese population[J].J Cancer Res Ther,2016,12(Supplement):C284-C287.
[19] McEwan P,Ward T,Chen CJ,et al.Estimating the incidence and prevalence of chronic hepatitis c infection in taiwan using back projection[J].Value Health Reg Issues,2014,3:5-11.
[20]杨杨,陈志军,侯铁军,等.西安市2008-2014年甲型病毒性肝炎流行病学特征分析[J].中华疾病控制杂志,2016,20(5):469-473.
[21]祝寒松,黄文龙,谢忠杭,等.福建省2005-2014年戊型病毒性肝炎流行病学特征分析[J].中国预防医学杂志,2016,17(7):544-546.
[22]孙校金,王富玲,郑微,等.2004-2015年中国甲型病毒性肝炎流行病学特征分析[J].中华预防医学杂志,2017,51(12):1091-1096.
[2] Park H,Jeong D,Nguyen P,et al.Economic and clinical burden of viral hepatitis in California:A population-based study with longitudinal analysis[J].PLoS One,2018,13(4):e0196452.
[3] Ma W,Soliman AS,Anwar WA,et al.Forecasted impacts of a sofosbuvir-based national hepatitis C treatment programme on Egypt′s hepatocellular cancer epidemic:simulation of alternatives[J].BMJ Glob Health,2018,3(2):e000572.
[4]国家卫生计生委办公厅关于印发传染病信息报告管理规范(2015年版)的通知(国卫办疾控发[2015]53号)[J].中华人民共和国国家卫生和计划生育委员会公报,2015(10):36-42.
[5]李扬,耿爱生,汪心海,等.中国病毒性肝炎流行状况GIS空间分析[J].中国卫生统计,2016,33(2):235-238.
[6] Zhu B,Liu J,Fu Y,et al.Spatio-Temporal Epidemiology of Viral Hepatitis in China(2003-2015):Implications for Prevention and Control Policies[J].Intl J Environ Res Public Health,2018,15(4):661.
[7]孙虹.2014年度全国法定传染病疫情情况[J].吉林医学信息,2015(2):26-27.
[8]张敏娜,袁月,貌盼勇,等.中国2004-2013年病毒性肝炎发病与死亡趋势分析[J].中华流行病学杂志,2015,36(2):144-147.
[9]徐爱强,张丽.中国病毒性肝炎血清流行病学调查的回顾与意义[J].中华预防医学杂志,2017,51(6):457-461.
[10]张万军,张瑾,袁兆虎,等.江苏省镇江市2004-2015年病毒性肝炎流行特征分析[J].中国卫生统计,2017,34(2):240-242.
[11]刘义文,蒲中枢,吉兆华,等.甘肃省武威市2005-2013年病毒性肝炎发病趋势分析[J].中国卫生统计,2016,33(1):148-149.
[12]洪佳冬,康燕,李建杰.广州市荔湾区2004-2013年病毒性肝炎流行病学特征分析[J].华南预防医学,2015,41(3):266-269.
[13]韩喜荣.北京市海淀区病毒性肝炎流行病学特征[J].中国卫生检验杂志,2014,24(16):2425-2427.
[14] Lee SW,Lee TY,Yang SS,et al.Prevalence of hepatitis B reactivation among chinese individuals with chronic hepatitis c treated with Pan-Oral direct-acting antivirals[J].Gastroenterol Res,2018,11(2):124-129.
[15]武荣,杜秀芳,王坤,等.临汾市尧都区2010-2015年病毒性肝炎流行病学特征分析[J].中国老年学杂志,2017,37(21):5446-5448.
[16]胡海洋,傅更锋,卢静,等.江苏省2005-2012年丙型肝炎流行特征分析[J].中华疾病控制杂志,2015,19(4):393-395.
[17] Zou X,Chow EP,Zhao P,et al.Rural-to-urban migrants are at high risk of sexually transmitted and viral hepatitis infections in China:a systematic review and meta-analysis[J].BMC Infect Dis,2014,14:490.
[18] Li L,Lan X.Association between hepatitis B virus/hepatitis C virus infection and primary hepatocellular carcinoma risk:A meta-analysis based on Chinese population[J].J Cancer Res Ther,2016,12(Supplement):C284-C287.
[19] McEwan P,Ward T,Chen CJ,et al.Estimating the incidence and prevalence of chronic hepatitis c infection in taiwan using back projection[J].Value Health Reg Issues,2014,3:5-11.
[20]杨杨,陈志军,侯铁军,等.西安市2008-2014年甲型病毒性肝炎流行病学特征分析[J].中华疾病控制杂志,2016,20(5):469-473.
[21]祝寒松,黄文龙,谢忠杭,等.福建省2005-2014年戊型病毒性肝炎流行病学特征分析[J].中国预防医学杂志,2016,17(7):544-546.
[22]孙校金,王富玲,郑微,等.2004-2015年中国甲型病毒性肝炎流行病学特征分析[J].中华预防医学杂志,2017,51(12):1091-1096.
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