高危农药助剂的危害及残留检测研究现状
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摘要
综述了农药中高危助剂自身毒性、环境毒性及对人类的危害和近年来农药助剂在食品中残留的检测方法。总结各国农药助剂管理现状,并针对重庆市场上农药(乳油)助剂的风险监测结果,关注农药助剂对农产品的潜在影响,以保护环境和人类免受风险评估缺失的有毒农药助剂的危害。
The toxicity, environmental toxicity and hazards on human of high risk adjuvants in pesticide were introduced and the detection methods of pesticide adjuvant residues in food in recent years were reviewed. The management status of pesticide adjuvant in various countries were also summarized. In view of risk monitoring results of pesticide(EC) adjuvants in Chongqing market, pay attention to the potential impact of pesticide additives on agricultural products, to protect environment and prevent human from toxic pesticide adjuvants that missing risk assessments.
The toxicity, environmental toxicity and hazards on human of high risk adjuvants in pesticide were introduced and the detection methods of pesticide adjuvant residues in food in recent years were reviewed. The management status of pesticide adjuvant in various countries were also summarized. In view of risk monitoring results of pesticide(EC) adjuvants in Chongqing market, pay attention to the potential impact of pesticide additives on agricultural products, to protect environment and prevent human from toxic pesticide adjuvants that missing risk assessments.
引文
[1]孔祥吉,卜元卿,郭欣妍,等.不同农药助剂的初级生物降解性研究[J].日用化学工业,2016,46(9):511-518.
[2]卜元卿,王昝畅,勇智,等.农药制剂中助剂使用状况调研及风险分析[J].农药,2014,53(12):932-936.
[3]LI Hui,JIANG Ze-jun,CAO Xiao-lin,et al.SPE/GC-MSDetermination of 2-Pyrrolidone,N-Methyl-2-pyrrolidone,and N-Ethyl-2-pyrrolidone in Liquid Pesticide Formulations[J].Chromatographia,2017,81(2):359-364.
[4]SURGAN M,COX C.Unidentified Inert Ingredients in Pesticides:Implications for Human and Environmental Health[J].Environ Health Perspect,2006,114(12):1803-1806.
[5]MESNAGE R,BERNAY B,SERALINI G E.Ethoxylated Adjuvants of Glyphosate-based Herbicides are Active Principles of Human Cell Ttoxicity[J].Toxicology,2013,313(2/3):122-128.
[6]MESNAGE R,DEFARGE N,SPIROUX DE VENDOMOIS J,et al.Major Pesticides are More Toxic to Human Cells than Their Declared Active Principles[J].Biomed Res Int,2014:179691.
[7]BEGGEL S,WERNER I,CONNON R E,et al.Sublethal Toxicity of Commercial Insecticide Formulations and Their Active Ingredients to Larval Fathead Minnow(Pimephales Promelas)[J].Sci Total Environ,2010,408(16):3169-3175.
[8]MANSANO A S,MOREIRA R A,PIEROZZI M,et al.Effects of Diuron and Carbofuran Pesticides in Their Pure and Commercial Forms on Paramecium Caudatum:The Use of Protozoan in Ecotoxicology[J].Environmental Pollution,2016,213:160-172.
[9]TRAN V,HOFFMAN N,MOFUNANAYA A,et al.Bifenthrin Inhibits Neurite Outgrowth in Differentiating PC12 Cells[J].Med Sci Monit,2006,12(2):57-62.
[10]PEIXOTO F.Comparative Effects of the Roundup and Glyphosate on Mitochondrial Oxidative Phosphorylation[J].Chemosphere,2005,61(8):1115-1122.
[11]孔祥吉,韦笑,王娜,等.聚氧乙烯型非离子表面活性剂类农药助剂的环境行为特性综述[J].农业资源与环境学报,2017,34(3):197-206.
[12]SURGAN M,CONDON M,COX C.Pesticide Risk Indicators:Unidentified Iinert Ingredients Compromise Their Integrity and Utility[J].Environ Manage,2010,45(4):834-841.
[13]KUCHARSKI M,SADOWSKI J,DOMARADZKI K.Degradation Rate of Chloridazon in Soil as Influenced by Adjuvants[J].Journal of Plant Protection Research,2012,52(1):114-117.
[14]KHAN M A,BROWN C D.Influence of Commercial Formulation on Leaching of Four Pesticides Through Soil[J].Science of the Total Environment,2016,573:1573-1579.
[15]KROGH K A,VEJRUP K V,MOGENSEN B B,et al.Liquid Chromatography-mass Spectrometry Method to Determine Alcohol Ethoxylates and Alkylamine Ethoxylates in Soil Interstitial Water,Ground Water and Surface Water Samples[J].Journal of Chromatography A,2002,957(1):45-47.
[16]PETROVIC′M,BARCELO′A D.Determination of Anionic and Nonionic Surfactants,Their Degradation Products,and Endocrine-disrupting Compounds in Sewage Sludge by Liquid Chromatography/mass Spectrometry[J].Anal Chem,2000,72(19):4560-4567.
[17]杜章留,潘波,张庆忠,等.农药助剂及其降解产物壬基酚在生姜及土壤中的残留检测[J].农药,2015,54(5):356-359.
[18]JOBLING S,BURN R W,THORPE K,et al.Statistical Modeling Suggests that Antiandrogens in Effluents from Wastewater Treatment Works Contribute to Widespread Sexual Disruption in Fish Living in English Rivers[J].Environ Health Perspect,2009,117(5):797-802.
[19]李正,潘波,林勇,等.3种农药助剂对野生食蚊鱼的急性毒性[J]农药,2013,52(5):354-356,359.
[20]HENRY M,BEGUIN M,REQUIER F,et al.A Common Pesticide Decreases Foraging Success and Survival in Honey Bees[J].Science,2012,336(6079):348-350.
[21]CHEN Jing,FINE J D,MULLIN C A.Are Organosilicon Surfactants Safe for Bees or Humans[J].Science of the Total Environment,2018,612:415-421.
[22]FINE J D,MULLIN C A,FRAZIER M T,et al.Field Residues and Effects of the Insect Growth Regulator Novaluron and Its Major Co-Formulant N-Methyl-2-pyrrolidone on Honey Bee Reproduction and Development[J].J Econ Entomol,2017,110(5):1993-2001.
[23]SAILLENFAIT A M,GALLISSOT F,LANGONNE′I,et al.Developmental Toxicity of N-Methyl-2-pyrrolidone Administered Orally to Rats[J].Food and Chemical Toxicology,2002,40(11):1705-1712.
[24]MOSTAFALOU S,ABDOLLAHI M.Pesticides:An Update of Human Exposure and Toxicity[J].Arch Toxicol,2017,91(2):549-599.
[25]VIEL J F,ROUGET F,WAREMBOURG C,et al.Behavioural Disorders in 6-Year-old Children and Pyrethroid Iinsecticide Exposure:the PELAGIE Mother-child Cohort[J].Occupational and Environmental Medicine,2017:1-7.
[26]MESNAGE R,ANTONIOU M N.Ignoring Adjuvant Toxicity Falsifies the Safety Profile of Commercial Pesticides[J].Front Public Health,2017(5):361.
[27]CHEN Jing,MULLIN C A.Quantitative Determination of Trisiloxane Surfactants in Beehive Environments Based on Liquid Chromatography Coupled to Mass Spectrometry[J].Environ Sci Technol,2013,47(16):9317-9323.
[28]王珊珊,刘广洋,杜欣蔚,等.顶空/气相色谱-质谱法同时测定蔬菜和水中5种挥发性农药助剂残留[J].分析试验室,2015,34(9):1026-1030.
[29]MESNAGE R,DEFARGE N,SPIROUX DE VENDOMOIS J,et al.Potential Toxic Effects of Glyphosate and Its Commercial Formulations Below Regulatory Limits[J].Food Chem Toxicol,2015,84:133-153.
[30]CHASSAING B,KOREN O,GOODRICH J K,et al.Dietary Emulsifiers Impact the Mouse Gut Microbiota Promoting Colitis and Metabolic Syndrome[J].Nature,2015,519(7541):92-96.
[31]潘波,杜章留,张庆忠,等.新型农药助剂在大蒜及土壤中的残留[J].热带农业科学,2016,36(7):87-92.
[32]杨锚,王淼,佘永新,等.环境内分泌干扰物辛基酚、壬基酚及短链壬基酚聚氧乙烯醚残留同步检测方法[J].农业环境科学学报,2014,33(7):1460-1464.
[33]LI Hui,JIANG Ze-jun,CAO Xiao-lin,et al.Simultaneous Determination of Three Pesticide Adjuvant Residues in Plant-derived Agro-products Using Liquid Chromatography-tandem Mass Spectrometry[J].J Chromatogr A,2017,1528:53-60.
[34]王以燕,张宗俭,巨育红,等.澳大利亚农药助剂管理[J].今日农药,2018(3):35-39.
[35]佚名.2022年全球农药助剂市场的市值将达到42.1亿美元[J].农药,2017,56(6):446.
[2]卜元卿,王昝畅,勇智,等.农药制剂中助剂使用状况调研及风险分析[J].农药,2014,53(12):932-936.
[3]LI Hui,JIANG Ze-jun,CAO Xiao-lin,et al.SPE/GC-MSDetermination of 2-Pyrrolidone,N-Methyl-2-pyrrolidone,and N-Ethyl-2-pyrrolidone in Liquid Pesticide Formulations[J].Chromatographia,2017,81(2):359-364.
[4]SURGAN M,COX C.Unidentified Inert Ingredients in Pesticides:Implications for Human and Environmental Health[J].Environ Health Perspect,2006,114(12):1803-1806.
[5]MESNAGE R,BERNAY B,SERALINI G E.Ethoxylated Adjuvants of Glyphosate-based Herbicides are Active Principles of Human Cell Ttoxicity[J].Toxicology,2013,313(2/3):122-128.
[6]MESNAGE R,DEFARGE N,SPIROUX DE VENDOMOIS J,et al.Major Pesticides are More Toxic to Human Cells than Their Declared Active Principles[J].Biomed Res Int,2014:179691.
[7]BEGGEL S,WERNER I,CONNON R E,et al.Sublethal Toxicity of Commercial Insecticide Formulations and Their Active Ingredients to Larval Fathead Minnow(Pimephales Promelas)[J].Sci Total Environ,2010,408(16):3169-3175.
[8]MANSANO A S,MOREIRA R A,PIEROZZI M,et al.Effects of Diuron and Carbofuran Pesticides in Their Pure and Commercial Forms on Paramecium Caudatum:The Use of Protozoan in Ecotoxicology[J].Environmental Pollution,2016,213:160-172.
[9]TRAN V,HOFFMAN N,MOFUNANAYA A,et al.Bifenthrin Inhibits Neurite Outgrowth in Differentiating PC12 Cells[J].Med Sci Monit,2006,12(2):57-62.
[10]PEIXOTO F.Comparative Effects of the Roundup and Glyphosate on Mitochondrial Oxidative Phosphorylation[J].Chemosphere,2005,61(8):1115-1122.
[11]孔祥吉,韦笑,王娜,等.聚氧乙烯型非离子表面活性剂类农药助剂的环境行为特性综述[J].农业资源与环境学报,2017,34(3):197-206.
[12]SURGAN M,CONDON M,COX C.Pesticide Risk Indicators:Unidentified Iinert Ingredients Compromise Their Integrity and Utility[J].Environ Manage,2010,45(4):834-841.
[13]KUCHARSKI M,SADOWSKI J,DOMARADZKI K.Degradation Rate of Chloridazon in Soil as Influenced by Adjuvants[J].Journal of Plant Protection Research,2012,52(1):114-117.
[14]KHAN M A,BROWN C D.Influence of Commercial Formulation on Leaching of Four Pesticides Through Soil[J].Science of the Total Environment,2016,573:1573-1579.
[15]KROGH K A,VEJRUP K V,MOGENSEN B B,et al.Liquid Chromatography-mass Spectrometry Method to Determine Alcohol Ethoxylates and Alkylamine Ethoxylates in Soil Interstitial Water,Ground Water and Surface Water Samples[J].Journal of Chromatography A,2002,957(1):45-47.
[16]PETROVIC′M,BARCELO′A D.Determination of Anionic and Nonionic Surfactants,Their Degradation Products,and Endocrine-disrupting Compounds in Sewage Sludge by Liquid Chromatography/mass Spectrometry[J].Anal Chem,2000,72(19):4560-4567.
[17]杜章留,潘波,张庆忠,等.农药助剂及其降解产物壬基酚在生姜及土壤中的残留检测[J].农药,2015,54(5):356-359.
[18]JOBLING S,BURN R W,THORPE K,et al.Statistical Modeling Suggests that Antiandrogens in Effluents from Wastewater Treatment Works Contribute to Widespread Sexual Disruption in Fish Living in English Rivers[J].Environ Health Perspect,2009,117(5):797-802.
[19]李正,潘波,林勇,等.3种农药助剂对野生食蚊鱼的急性毒性[J]农药,2013,52(5):354-356,359.
[20]HENRY M,BEGUIN M,REQUIER F,et al.A Common Pesticide Decreases Foraging Success and Survival in Honey Bees[J].Science,2012,336(6079):348-350.
[21]CHEN Jing,FINE J D,MULLIN C A.Are Organosilicon Surfactants Safe for Bees or Humans[J].Science of the Total Environment,2018,612:415-421.
[22]FINE J D,MULLIN C A,FRAZIER M T,et al.Field Residues and Effects of the Insect Growth Regulator Novaluron and Its Major Co-Formulant N-Methyl-2-pyrrolidone on Honey Bee Reproduction and Development[J].J Econ Entomol,2017,110(5):1993-2001.
[23]SAILLENFAIT A M,GALLISSOT F,LANGONNE′I,et al.Developmental Toxicity of N-Methyl-2-pyrrolidone Administered Orally to Rats[J].Food and Chemical Toxicology,2002,40(11):1705-1712.
[24]MOSTAFALOU S,ABDOLLAHI M.Pesticides:An Update of Human Exposure and Toxicity[J].Arch Toxicol,2017,91(2):549-599.
[25]VIEL J F,ROUGET F,WAREMBOURG C,et al.Behavioural Disorders in 6-Year-old Children and Pyrethroid Iinsecticide Exposure:the PELAGIE Mother-child Cohort[J].Occupational and Environmental Medicine,2017:1-7.
[26]MESNAGE R,ANTONIOU M N.Ignoring Adjuvant Toxicity Falsifies the Safety Profile of Commercial Pesticides[J].Front Public Health,2017(5):361.
[27]CHEN Jing,MULLIN C A.Quantitative Determination of Trisiloxane Surfactants in Beehive Environments Based on Liquid Chromatography Coupled to Mass Spectrometry[J].Environ Sci Technol,2013,47(16):9317-9323.
[28]王珊珊,刘广洋,杜欣蔚,等.顶空/气相色谱-质谱法同时测定蔬菜和水中5种挥发性农药助剂残留[J].分析试验室,2015,34(9):1026-1030.
[29]MESNAGE R,DEFARGE N,SPIROUX DE VENDOMOIS J,et al.Potential Toxic Effects of Glyphosate and Its Commercial Formulations Below Regulatory Limits[J].Food Chem Toxicol,2015,84:133-153.
[30]CHASSAING B,KOREN O,GOODRICH J K,et al.Dietary Emulsifiers Impact the Mouse Gut Microbiota Promoting Colitis and Metabolic Syndrome[J].Nature,2015,519(7541):92-96.
[31]潘波,杜章留,张庆忠,等.新型农药助剂在大蒜及土壤中的残留[J].热带农业科学,2016,36(7):87-92.
[32]杨锚,王淼,佘永新,等.环境内分泌干扰物辛基酚、壬基酚及短链壬基酚聚氧乙烯醚残留同步检测方法[J].农业环境科学学报,2014,33(7):1460-1464.
[33]LI Hui,JIANG Ze-jun,CAO Xiao-lin,et al.Simultaneous Determination of Three Pesticide Adjuvant Residues in Plant-derived Agro-products Using Liquid Chromatography-tandem Mass Spectrometry[J].J Chromatogr A,2017,1528:53-60.
[34]王以燕,张宗俭,巨育红,等.澳大利亚农药助剂管理[J].今日农药,2018(3):35-39.
[35]佚名.2022年全球农药助剂市场的市值将达到42.1亿美元[J].农药,2017,56(6):446.
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