新疆维吾尔自治区2008～2017年手足口病流行病学及病原学监测分析

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英文篇名：Epidemiological Analyses of Hand,Foot and Mouth Disease in Xinjiang Uygur Autonomous Region,China,during 2008～2017 作者：黄永迪 ; 邓红 ; 阿依古丽·伊尔哈力 ; 樊旭成 ; 吴海燕 ; 朱建疆 ; 张璇 ; 赵俊 ; 宋欣欣 ; 岳锡宏 英文作者：HUANG Yongdi;DENG Hong;AYIGULI Yierhali;FAN Xucheng;WU Haiyan;ZHU Jianjiang;ZHANG Xuan;ZHAO Jun;SONG Xinxin;YUE Xihong;Center for Disease Prevention and Control OF Xinjiang Uygur Autonomous Region;Center for Disease Prevention and Control OF Urumqi Prefecture;Center for Disease Prevention and Control OF Bayinguoleng Prefecture;Center for Disease Prevention and Control OF Changji Prefecture; 关键词：手足口病(HFMD) ; 新疆维吾尔自治区 ; 流行病学 ; 病原学 英文关键词：Hand,foot and mouth disease(HFMD);;Xinjiang Uygur Autonomous Region;;Epidemiology;;Pathogen 中文刊名：BDXB 英文刊名：Chinese Journal of Virology 机构：新疆维吾尔自治区疾病预防控制中心;乌鲁木齐市疾病预防控制中心;巴州疾病预防控制中心;昌吉州疾病预防控制中心; 出版日期：2019-01-08 10:33 出版单位：病毒学报 年：2019 期：v.35 基金：新疆自治区自然科学基金项目(项目号:2016D01A063),题目:新疆手足口病非优势肠道病毒的型别鉴定及其变异规律研究~~ 语种：中文; 页：BDXB201901013 页数：5 CN：01 ISSN：11-1865/R 分类号：91-95

摘要

分析2008～2017年新疆维吾尔手足口病流行病学和病原学特征。采用描述性流行病学的方法,对2008～2017年国家疾病监测信息报告管理系统报告的手足口病例和新疆手足口病网络实验室数据的进行分析。2008～2017年新疆累计报告手足口病例68 820例,重症107例,死亡10例,年均发病率为31.33/10万;病例主要集中在乌鲁木齐市、伊犁州、昌吉州和塔城地区,占总病例数68.26%;5月～7月为发病高峰,病例以1岁～4岁儿童为主,占总病例数的74.46%,散居儿童和幼托儿童分别占51.52%和40.34%;对12 345例手足口病例标本进行核酸检测,阳性8 872例,阳性率71.87%,普通病例中肠道病毒71型(EV-A71)、柯萨奇病毒A组16型(CV-Al6)和其他肠道病毒分别占33.01%、40.33%和26.65%,重症和死亡病例的病原型别均以EV-A71为主,分别占91.03%和100%。新疆1岁～4岁的儿童为手足口病主要发病人群,不同地区发病水平不同,手足口病病原谱呈现EV-A71、CV-A16和其他EV交替流行态势。
        To analyze the epidemiological and pathogenic characteristics of hand,foot and mouth disease(HFMD)in Xinjiang Uygur Autonomous Region(XUAR),China,during 2008～2017. Cases of HFMD in XUAR during 2008～2017 were downloaded from the Chinese National Notifiable Infectious Disease Reporting System. Laboratory results were downloaded from the National Notifiable Disease Surveillance System and Regional HFMD Laboratory Network. These data were analyzed using descriptive epidemiological methods. A total of 68,820 HFMD cases were reported in XUAR from 2008 to 2017,including 107 severe cases and 10 death cases;the annual incidence was 31.33 per 10 million. The majority of reported cases were distributed in Urumqi,Yili,Changji and Tacheng. The peak incidence appeared from May to July. Children aged 1～4 years accounted for 74.46% of cases. Children living in different areas and children staying in kindergartens accounted for 51.52% and 40.34% of cases,respectively. Overall,12,345 cases were tested,and 8,872 of them were confirmed by laboratory tests(71.87%). EV-A71,CV-A16 and other enteric viruses accounted for 33.01%,40.33% and 26.65% of cases,respectively. Severe cases and deaths were caused by EV -A71,accounting for 91.03% and 100%,respectively. These data suggested that children aged 1～4 years were the major population group,the epidemic was different in different areas,and EV-A71,CV-A16 and other enteric viruses were the major pathogens of HFMD.

引文

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