运脾祛湿解毒通络法在类风湿关节炎中的治法探讨
|
摘要
类风湿关节炎(RA)病理变化主要表现为关节破坏和功能丧失。中医学认为,脾虚是RA发病的内在条件,湿浊是其进展的潜在诱因,毒邪是其病理基础,络阻是其主要临床表现。中医以运脾祛湿、解毒通络法为治疗RA的基本法则,健脾除邪以固本,解毒以调节机体免疫功能,通络可促进关节周围血液循环,预防及减轻关节变形。
The pathological changes of rheumatoid arthritis are mainly manifested in joint destruction and loss of function. In traditional Chinese medicine,splenic asthenia is the inherent condition of RA pathogenesis;turbid dampness is the potential incentive for its progress;toxin is its pathology,and collateral resistance is its main clinical manifestations. In TCM,tonifying spleen,eliminating dampness,detoxification and dredging collateral method is used as the basic law to treat RA. Strengthening spleen can remove pathogenic factors and consolidate the constitution. Detoxification can adjust the body immunologic function. Dredging collateral can promote blood circula-tion around the joints and reduce joint deformation.
The pathological changes of rheumatoid arthritis are mainly manifested in joint destruction and loss of function. In traditional Chinese medicine,splenic asthenia is the inherent condition of RA pathogenesis;turbid dampness is the potential incentive for its progress;toxin is its pathology,and collateral resistance is its main clinical manifestations. In TCM,tonifying spleen,eliminating dampness,detoxification and dredging collateral method is used as the basic law to treat RA. Strengthening spleen can remove pathogenic factors and consolidate the constitution. Detoxification can adjust the body immunologic function. Dredging collateral can promote blood circula-tion around the joints and reduce joint deformation.
引文
[1]丁德经,周学平.辨病与辨证相结合治疗类风湿性关节炎[J].中华中医药杂志,2016,31(12):5058-5061.
[2]Firestein GS,Mclnnes IB.Immunopathogenesis of rheumatoid arthritis[J].Immunity,2007,46(2):183-196.
[3]谢志军,温成平,王新昌,等.解毒通络祛湿法治疗活动期类风湿性关节炎的临床研究[J].中国中医基础医学杂志,2008,14(11):865-867.
[4]温成平,金晨宇,许志良,等.解毒通络利湿方及拆方对实验性类风湿性关节炎抗炎镇痛及调节免疫作用的比较研究[J].中国中药杂志,2007,32(13):1306-1310.
[5]李强,邹升产.类风湿性关节炎的发生与中医脾虚关系的理论探讨[J].新疆中医药,2003,21(5):2-4.
[6]姜小帆,曾进,石亮.类风湿性关节炎辨证分型及证候要素分布的文献研究[J].中国实验方剂学杂志,2014,29(8):196-200.
[7]朱震,张世勤,汪悦,等.类风湿性关节炎中医证素分布[J].南京中医药大学学报,2012,28(6):531-534.
[8]陈昫,胡玲,龚琳,等.脾胃创新理论研究钩玄[J].中华中医药杂志,2014,29(4):1001-1003.
[9]王兴柱.清热通痹汤治疗活动期类风湿性关节炎38例临床观察[J].山西中医,2008,24(9):23-25.
[10]李梢,王永炎.类风湿性关节炎从“络”辨治的理论体系初探[J].中医杂志,2002,43(2):85-88.
[11]刘健,黄传兵,汪元,等.健脾化湿通络法对类风湿关节炎关节外病变的影响及机制研究[J].风湿病与关节炎,2012,1(2):8-11.
[12]赫军,李丽华,郑永昌,等.娄多峰辨治类风湿关节炎经验[J].中国中医急症,2013,22(9):1536.
[13]刘运磊,景蓉,刘烨.刘烨教授运用香砂六君子汤治疗慢性胃炎经验[J].陕西中医学院学报,2011,34(3):19-20.
[14]高应兵,张智斌,刘怀,等.杨仓良从毒辨治类风湿性关节炎经验[J].新中医,2012,44(12):181-182.
[15]闫军堂,刘晓倩,王雪茜,等.王庆国教授治疗类风湿性关节炎经验[J].中华中医药杂志,2012,27(9):2341-2344.
[2]Firestein GS,Mclnnes IB.Immunopathogenesis of rheumatoid arthritis[J].Immunity,2007,46(2):183-196.
[3]谢志军,温成平,王新昌,等.解毒通络祛湿法治疗活动期类风湿性关节炎的临床研究[J].中国中医基础医学杂志,2008,14(11):865-867.
[4]温成平,金晨宇,许志良,等.解毒通络利湿方及拆方对实验性类风湿性关节炎抗炎镇痛及调节免疫作用的比较研究[J].中国中药杂志,2007,32(13):1306-1310.
[5]李强,邹升产.类风湿性关节炎的发生与中医脾虚关系的理论探讨[J].新疆中医药,2003,21(5):2-4.
[6]姜小帆,曾进,石亮.类风湿性关节炎辨证分型及证候要素分布的文献研究[J].中国实验方剂学杂志,2014,29(8):196-200.
[7]朱震,张世勤,汪悦,等.类风湿性关节炎中医证素分布[J].南京中医药大学学报,2012,28(6):531-534.
[8]陈昫,胡玲,龚琳,等.脾胃创新理论研究钩玄[J].中华中医药杂志,2014,29(4):1001-1003.
[9]王兴柱.清热通痹汤治疗活动期类风湿性关节炎38例临床观察[J].山西中医,2008,24(9):23-25.
[10]李梢,王永炎.类风湿性关节炎从“络”辨治的理论体系初探[J].中医杂志,2002,43(2):85-88.
[11]刘健,黄传兵,汪元,等.健脾化湿通络法对类风湿关节炎关节外病变的影响及机制研究[J].风湿病与关节炎,2012,1(2):8-11.
[12]赫军,李丽华,郑永昌,等.娄多峰辨治类风湿关节炎经验[J].中国中医急症,2013,22(9):1536.
[13]刘运磊,景蓉,刘烨.刘烨教授运用香砂六君子汤治疗慢性胃炎经验[J].陕西中医学院学报,2011,34(3):19-20.
[14]高应兵,张智斌,刘怀,等.杨仓良从毒辨治类风湿性关节炎经验[J].新中医,2012,44(12):181-182.
[15]闫军堂,刘晓倩,王雪茜,等.王庆国教授治疗类风湿性关节炎经验[J].中华中医药杂志,2012,27(9):2341-2344.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |