2014年上海市金山区新报告HIV/AIDS流行病学特征及CD4+T淋巴细胞检测情况
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摘要
目的了解上海市金山区新报告人类免疫缺陷病毒(感染者)和艾滋病(患者)(HIV/AIDS)流行特征及机体免疫状况。方法分析流行病学资料,应用流式细胞计数仪对新报告HIV/AIDS进行CD4+T淋巴细胞检测。结果 2014年金山区新报告HIV/AIDS 116例,男女性别比为6.25∶1;年龄以20~49岁为主,占75.00%。来源主要为检测咨询占52.59%,其次为其他就诊者检测占47.41%。感染途径性传播占99.14%,其中同性传播占65.52%,异性传播占33.62%。新报告HIV/AIDS CD4+T淋巴细胞<200个/ml的占48.67%。AIDS组CD4+T淋巴细胞低于HIV感染者组。结论 2014年金山区新报告的HIV/AIDS以男性中青年为主,感染途径以性传播为主,随着疾病的进展,CD4+T淋巴细胞持续降低。应扩大高危人群的干预和动员检测,达到早发现、早治疗、有效控制AIDS疫情的目的。
[Objective] To learn the epidemic characteristics and immune status of the newly reported HIV/AIDS patients in Jinshan District of Shanghai. [Methods]The epidemiological data were analyzed,and the flow cytometry was used to detect the CD4+T lymphocytes in newly reported HIV/AIDS patients. [Results]There were 116 newly reported HIV/AIDS patients in Jinshan District in 2014,and the male-to-female ratio was 6.2 5 ∶1. Most of patients were people aged 20-49 years old,accounting for75.00%.The main source of the patients was test counseling,accounting for 52.59%,followed by visits from other inspection,accounting for 47.41%.The sexual transmission(99.14%) was the main infection route,while the homosexual transmission and heterosexual transmission accounted for 65.52% and 33.62% respectively.Among newly reported HIV/AIDS patients,48.67% had the result of CD4+Tlymphocytes count less than 200/ml. The number of CD4+Tlymphocytes in AIDS patients was lower than that in HIV infections.[Conclusion]The newly reported HIV/AIDS patients in Jinshan District of Shanghai in 2014 are mainly young and middle-aged males,and the main infection route is sexual transmission.The number of CD4+Tlymphocytes is decreasing with the disease progresses. It is necessary to expand the interventions and mobilization detection among AIDS high-risk groups,to achieve the goals of early detection,early treatment,and effective control of AIDS epidemic.
[Objective] To learn the epidemic characteristics and immune status of the newly reported HIV/AIDS patients in Jinshan District of Shanghai. [Methods]The epidemiological data were analyzed,and the flow cytometry was used to detect the CD4+T lymphocytes in newly reported HIV/AIDS patients. [Results]There were 116 newly reported HIV/AIDS patients in Jinshan District in 2014,and the male-to-female ratio was 6.2 5 ∶1. Most of patients were people aged 20-49 years old,accounting for75.00%.The main source of the patients was test counseling,accounting for 52.59%,followed by visits from other inspection,accounting for 47.41%.The sexual transmission(99.14%) was the main infection route,while the homosexual transmission and heterosexual transmission accounted for 65.52% and 33.62% respectively.Among newly reported HIV/AIDS patients,48.67% had the result of CD4+Tlymphocytes count less than 200/ml. The number of CD4+Tlymphocytes in AIDS patients was lower than that in HIV infections.[Conclusion]The newly reported HIV/AIDS patients in Jinshan District of Shanghai in 2014 are mainly young and middle-aged males,and the main infection route is sexual transmission.The number of CD4+Tlymphocytes is decreasing with the disease progresses. It is necessary to expand the interventions and mobilization detection among AIDS high-risk groups,to achieve the goals of early detection,early treatment,and effective control of AIDS epidemic.
引文
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[9]JC考德威尔.亚洲的HIV/AIDS水平将达到撒哈拉以南非洲的水平吗[J].国外社会科学,2007(1):98-99.
[10]郜桂菊,张福杰,姚均,等.HIV感染者/AIDS患者CD4+细胞计数与机会性感染对应关系的临床分析[J].中国艾滋病性病,2005,11(4):241-243.
[11]KITAHATA MM,GANGE SJ,ABRAHAM AG,et al.Effect of early versus deferred antiretroviral therapy for HIV on survival[J].New Engl J Med,2009,360(18):1815-1826.
[12]GALLANT JE.When to start antiretroviral therapy NA-ACCORD stimulates the debate[J].AIDS Read,2009,19(2):49-50.
[13]中华医学会感染病分会艾滋病学组.艾滋病诊疗指南[J].中华传染病杂志,2006,24(2):133-144.
[14]杨常敏,余爱玲,周莹荃,等.艾滋病患者不同基线CD4水平抗病毒疗效分析[J].中国公共卫生,2014,30(8):1073-1074.
[2]黄龙,郑定容,杨庆旬.深圳市HIV/AIDS流行状况分析[J].中国热带医学,2006,6(3):419-420.
[3]李桀,陈曦,覃碧云,等.老年HIV感染者感染HIV相关危险因素调查[J].实用预防医学,2010,17(2):227-229.
[4]汪宁.中国艾滋病流行的一些新动向[J].中华流行病学杂志,2010,31(11):1205-1209.
[5]李雷,还锡萍,徐金水,等.江苏省2006—2008年艾滋病高危人群哨点监测报告[J].江苏预防医学,2010,21(2):1-3.
[6]何文淑,杨诚.雨花台区2006—2010年艾滋病疫情流行病学分析[J].基层医学论坛,2011,15(3):268-269.
[7]张丽芬,梅林,乔晓春,等.太原市MSM人群的认知态度对安全套使用行为和意向的影响[J].中国艾滋病性病,2009,15(2):124-127.
[8]王婷,张睿孚,马菲,等.太原市高危人群艾滋病相关知识与行为状况调查[J].卫生研究,2010,39(1):77-79.
[9]JC考德威尔.亚洲的HIV/AIDS水平将达到撒哈拉以南非洲的水平吗[J].国外社会科学,2007(1):98-99.
[10]郜桂菊,张福杰,姚均,等.HIV感染者/AIDS患者CD4+细胞计数与机会性感染对应关系的临床分析[J].中国艾滋病性病,2005,11(4):241-243.
[11]KITAHATA MM,GANGE SJ,ABRAHAM AG,et al.Effect of early versus deferred antiretroviral therapy for HIV on survival[J].New Engl J Med,2009,360(18):1815-1826.
[12]GALLANT JE.When to start antiretroviral therapy NA-ACCORD stimulates the debate[J].AIDS Read,2009,19(2):49-50.
[13]中华医学会感染病分会艾滋病学组.艾滋病诊疗指南[J].中华传染病杂志,2006,24(2):133-144.
[14]杨常敏,余爱玲,周莹荃,等.艾滋病患者不同基线CD4水平抗病毒疗效分析[J].中国公共卫生,2014,30(8):1073-1074.
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