Myocardial Perfusion Magnetic Resonance Imaging Using Sliding-Window Conjugate-Gradient Highly Constrained Back-Projection Reconstruction for Detection of Coronary Artery Disease

详细信息	查看全文 | 推荐本文 |

• 作者：Heng Ma ; MD^a ; ^b ; ^&dagger ; ; Jun Yang ; MD^b ; ^&dagger ; ; Jing Liu ; MD^b ; ^&dagger ; ; Lan Ge ; PhD^c ; Jing An ; MD^d ; Qing Tang ; MD^e ; Han Li ; MD^e ; Yu Zhang ; MD^a ; David Chen ; PhD^c ; Yong Wang ; MD^f ; Jiabin Liu ; MD^a ; Zhigang Liang ; MD^a ; Kai Lin ; MD^c ; Lixin Jin ; MD^g ; Xiaoming Bi ; PhD^h ; Kuncheng Li ; MD^a ; ^{likuncheng55@yahoo.com.cn} ; Debiao Li ; PhD^c
• 刊名：The American Journal of Cardiology
• 出版年：2012
• 期刊代码：5_00029149
• 类别：med
• 出版时间：15 April, 2012
• 卷：109
• 期：8
• 页码：1137-1141
• 文件大小：799 K

摘要

Myocardial perfusion magnetic resonance imaging (MRI) with sliding-window conjugate-gradient highly constrained back-projection reconstruction (SW-CG-HYPR) allows whole left ventricular coverage, improved temporal and spatial resolution and signal/noise ratio, and reduced cardiac motion-related image artifacts. The accuracy of this technique for detecting coronary artery disease (CAD) has not been determined in a large number of patients. We prospectively evaluated the diagnostic performance of myocardial perfusion MRI with SW-CG-HYPR in patients with suspected CAD. A total of 50 consecutive patients who were scheduled for coronary angiography with suspected CAD underwent myocardial perfusion MRI with SW-CG-HYPR at 3.0 T. The perfusion defects were interpreted qualitatively by 2 blinded observers and were correlated with x-ray angiographic stenoses 鈮?0%. The prevalence of CAD was 56%. In the per-patient analysis, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of SW-CG-HYPR was 96%(95%confidence interval 82%to 100%), 82%(95%confidence interval 60%to 95%), 87%(95%confidence interval 70%to 96%), 95%(95%confidence interval 74%to100%), and 90%(95%confidence interval 82%to 98%), respectively. In the per-vessel analysis, the corresponding values were 98%(95%confidence interval 91%to 100%), 89%(95%confidence interval 80%to 94%), 86%(95%confidence interval 76%to 93%), 99%(95%confidence interval 93%to 100%), and 93%(95%confidence interval 89%to 97%), respectively. In conclusion, myocardial perfusion MRI using SW-CG-HYPR allows whole left ventricular coverage and high resolution and has high diagnostic accuracy in patients with suspected CAD.