Pyogenic liver abscess treated by percutaneous catheter drainage: MDCT measurement for treatment outcome

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• 作者：Wen-I Liao^a ; Shih-Hung Tsai^a ; Chih-Yung Yu^b ; Guo-Shu Huang^b ; Yen-Yue Lin^a ; Ching-Wang Hsu^a ; Hsian-He Hsu^b ; Wei-Chou Chang^b ; ^c ; ^{weichou.chang@gmail.com}
• 关键词：Pyogenic liver abscess ; Percutaneous catheter drainage ; Multidetector-row computed tomography ; CT attenuation ; Gas
• 刊名：European Journal of Radiology
• 出版年：2012
• 期刊代码：93_0720048x
• 类别：med
• 出版时间：April, 2012
• 卷：81
• 期：4
• 页码：609-615
• 文件大小：620 K

摘要

Objective

To analyze multidetector computed tomographic (MDCT) parameters in patients with pyogenic liver abscess (PLA), and to identify which parameters can be predicted percutaneous catheter drainage (PCD) treatment outcome.

Materials and methods

Clinical, laboratory and MDCT findings of 175 patients with PLA who had undergone PCD were retrospectively reviewed. All abscesses shown on MDCT were evaluated for size, margin, attenuation values, location, number of large (>3 cm) abscesses, presence of a cystic component, presence of gas, and the shortest length to the liver capsule. Univariate and multivariate analyses of the MDCT parameters that affect PCD treatment outcome was performed. For continuous data of MDCT parameters (abscess size and the shortest length), we used receiver-operating-characteristic (ROC) curve to determine the optimal cut-off values.

Results

PCD was failed in 32 patients and the overall failure rate was 18.28%. Multivariate analysis revealed that PCD failure was predicted by the presence of gas (odds ratio [OR], 42.67), a large abscess (OR 1.21), low minimal attenuation values (OR 1.02), wide range of attenuation values (OR 1.01), a shorter length to the liver capsule (OR 0.09) and lack of a cystic component (OR 0.09) of the PLA. ROC curve showed that the shortest length less than 0.25 cm and an abscess size greater than 7.3 cm were the optimal cut-off values predicting PCD treatment failure.

Conclusion

Among these MDCT parameters, gas formation within PLA was the most important predictor for PCD failure. Surgical intervention might be considered early in high-risk patients of PCD failure.