• 作者：Juan Perozo-Romero ; Mery Guerra-Velá ; squez ; Eduardo Reyna-Villasmil ; ^{sippenbauch@gmail.com} ; Jorly Mejia-Montilla ; Nadia Reyna-Villasmil ; Duly Torres-Cepeda ; Joel Santos-Bolí ; var ; Helen de Nobrega-Correa
• 关键词：Homocisteí ; na ; Preeclampsia ; Neonato
• 刊名：Progresos de Obstetricia y Ginecolog铆a
• 出版年：2011
• 期刊代码：pca294_03045013
• 类别：med
• 出版时间：August 2011
• 卷：54
• 期：8
• 页码：408-412
• 文件大小：171 K

Objective

To compare serum homocysteine concentrations in the newborns of preeclamptic patients and normotensive pregnant women.

Methods

Thirty-five preeclamptic patients and their newborns (group A; cases) and 35 normotensive pregnant women and their newborns (group B; controls) were selected. Maternal-neonatal homocysteine concentrations and neonatal weight were evaluated in both groups.

Results

Statistically significant differences were found in gestational age, systolic and diastolic blood pressure and the presence of proteinuria (p<0.05). Maternal homocysteine concentrations were higher in group A than in group B (p<0.05). Mean neonatal weight was significantly lower in group A than in group B (p<0.05). Neonatal homocysteine concentrations were higher in group A than in group B (p<0.05). When the homocysteine concentrations of newborns were correlated, there was a moderate, positive and significant correlation with maternal homocysteine concentrations and a moderate, negative and significant correlation with neonatal weight (p<0.05).

Conclusion

Homocysteine concentrations were significantly higher in the newborns of preeclamptic patients than in those of normotensive pregnant women.