Primary cardiac plasmablastic (diffuse large B-cell) lymphoma mimicking left ventricular aneurysm with mural thrombus

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• 作者：Dylan V. Miller ; Farouk Mookadam ; Martina Mookadam ; William D. Edwards ; William R. Macon
• 关键词：Non-Hodgkin lymphoma ; Cardiac neoplasms ; Epstein– ; Barr virus
• 刊名：Cardiovascular Pathology
• 出版年：2007
• 期刊代码：46_10548807
• 类别：med
• 出版时间：March-April 2007
• 卷：16
• 期：2
• 页码：111-114
• 文件大小：608 K

摘要

Primary cardiac lymphoma is rare and is usually of the non-Hodgkin type. By definition, it involves only the heart and the pericardium, with no evidence of extracardiac disease. Primary cardiac lymphoma accounts for 1%of primary cardiac tumors and 0.5%of extranodal lymphomas [Gowda RM, Kahn RA. Clinical perspectives of primary cardiac lymphoma. Angiology 2003;54(5):599–604]. On the other hand, secondary cardiac involvement can occur in approximately 20%of patients with disseminated extracardiac lymphoma [Gowda RM, Kahn RA. Clinical perspectives of primary cardiac lymphoma. Angiology 2003;54(5):599–604]. The majority of primary cardiac lymphomas are diffuse large B-cell lymphomas with centroblastic or immunoblastic cytologic features. Herein, we describe an exceptional case of a primary cardiac plasmablastic variant of diffuse large B-cell lymphoma (Epstein–Barr virus–positive) presenting in an immunocompetent host with chest pain that mimicked a left ventricular apical thrombus.