Endiandric Acid Analogues from the Roots of Beilschmiedia erythrophloia

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• 作者：Ping-Shin Yang ; Ming-Jen Cheng ; Chien-Fang Peng ; Jih-Jung Chen ; Ih-Sheng Chen
• 刊名：Journal of Natural Products
• 出版年：2009
• 出版时间：January 23, 2009
• 年：2009
• 卷：72
• 期：1
• 页码：53-58
• 全文大小：157K
• 年卷期：v.72,no.1(January 23, 2009)
• ISSN：1520-6025

文摘

Investigation of the roots of Beilschmiedia erythrophloia has led to the isolation of seven new endiandric acid analogues, erythrophloins A−F (1−6) and beilcyclone A (7), together with 11 known compounds. The structures of 1−7 were determined using spectroscopic techniques. Two constituents, erythrophloin C (3) and suberosol B (8), exhibited antitubercular activity against Mycobacterium tuberculosis H37Rv, showing MIC values of 50 and 28.9 μg/mL, respectively.