One-Pot Synthesis of Rotationally Restricted, Conjugatable, BODIPY Derivatives from Phthalides

详细信息    查看全文

• 作者：Mayca del Río ; Fernando Lobo ; J. Cristobal LópezAinhoa Oliden ; Jorge Bañuelos ; Iñigo López-ArbeloaInmaculada Garcia-Moreno ; Ana M. Gómez
• 刊名：Journal of Organic Chemistry
• 出版年：2017
• 出版时间：January 20, 2017
• 年：2017
• 卷：82
• 期：2
• 页码：1240-1247
• 全文大小：499K
• ISSN：1520-6904

文摘

O-Ethylation of phthalides with Meerwein’s reagent followed by reaction of the ensuing salts with pyrrole, results in the formation of 5-alkoxy-5-phenyl dipyrromethane derivatives, which function as ready precursors of ortho-substituted 8-aryl BODIPY derivatives by reaction with borontrifluoride etherate, an overall process that can be carried out in a one-pot operation.