Copper-Catalyzed Cascade Cycloamination of α-Csp3–H Bond of N-Aryl Ketimines with Azides: Access to Quinoxalines

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• 作者：Tengfei Chen ; Xun Chen ; Jun Wei ; Dongen Lin ; Ying Xie ; Wei Zeng
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：May 6, 2016
• 年：2016
• 卷：18
• 期：9
• 页码：2078-2081
• 全文大小：380K
• 年卷期：0
• ISSN：1523-7052

文摘

A copper-catalyzed cycloamination of α-Csp³–H bond of N-aryl ketimines with sodium azide has been developed. This methodology provides an efficient access to quinoxalines and features mild reaction conditions and readily available ketimines with diverse functional group tolerance.