Synthesis and Structure of Corona[6](het)arenes Containing Mixed Bridge Units

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• 作者：Zhan-Da Fu ; Qing-Hui Guo ; Liang Zhao ; De-Xian Wang ; Mei-Xiang Wang
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：June 3, 2016
• 年：2016
• 卷：18
• 期：11
• 页码：2668-2671
• 全文大小：346K
• 年卷期：0
• ISSN：1523-7052

文摘

A one-pot nucleophilic aromatic substitution reaction of 3,6-dichlorotetrazine with various diphenols and dibenzenethiols produced corona[4]arene[2]tetrazines that contain mixed oxygen, sulfide, methylene, and sulfone linkages. Macrocyclic ring transformations employing an inverse-electron-demand Diels–Alder reaction of tetrazine moieties with enamines and the subsequent sulfide oxidation reaction afforded diverse corona[4]arene[2]pyridazines. The acquired corona[6]arenes adopted three types of conformational structures in the crystalline state.