Synthesis of S-Aryl Phosphorothioates by Copper-Catalyzed Phosphorothiolation of Diaryliodonium and Arenediazonium Salts

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• 作者：Liangliang Zhang ; Pengbo Zhang ; Xueqin Li ; Jian Xu ; Guo Tang ; Yufen Zhao
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：July 1, 2016
• 年：2016
• 卷：81
• 期：13
• 页码：5588-5594
• 全文大小：478K
• 年卷期：0
• ISSN：1520-6904

文摘

Green methods for the synthesis of S-aryl phosphorothioates have been developed based on copper-catalyzed multicomponent reactions involving diaryliodonium/arenediazonium salts, elemental sulfur, and R₂P(O)H compounds. Most target products are obtained with these two methods in good to high yields at room temperature. These transformations allow the direct formation P–S and C–S bonds in one reaction.