The accurate prediction of the conditions of a pressurized jet upon its expansion to atmospheric pressure is of fundamental importance in assessing the consequences associated with accidental releases of hazardous fluids from pressurized containments. An integral multiphase compressible jet expansion model which for the first time accounts for turbulence generation is presented. Real fluid behavior is accounted for applying a suitable equation of state. By use of the accidental release of two-phase CO2 from a pressurized system as an example, the proposed model is shown to provide far better predictions of the fully expanded jet momentum and hence its downstream flow characteristics as compared to existing integral models where the impact of turbulence generation is ignored.