Small-Molecule Detection in Thiol鈥揧ne Nanocomposites via Surface-Enhanced Raman Spectroscopy

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• 作者：Darryl A. Boyd ; Francisco J. Bezares ; Dennis B. Pacardo ; Maraizu Ukaegbu ; Charles Hosten ; Frances S. Ligler
• 刊名：Analytical Chemistry
• 出版年：2014
• 出版时间：December 16, 2014
• 年：2014
• 卷：86
• 期：24
• 页码：12315-12320
• 全文大小：328K
• ISSN：1520-6882

文摘

Surface-enhanced Raman spectroscopy (SERS) is generally performed on planar surfaces, which can be difficult to prepare and may limit the interaction of the sensing surface with targets in large volume samples. We propose that nanocomposite materials can be configured that both include SERS probes and provide a high surface area-to-volume format, i.e., fibers. Thiol鈥搚ne nanocomposite films and fibers were fabricated using exposure to long-wave ultraviolet light after the inclusion of gold nanoparticles (AuNPs) functionalized with thiophenol. A SERS response was observed that was proportional to the aggregation of the AuNPs within the polymers and the amount of thiophenol present. Overall, this proof-of-concept fabrication of SERS active polymers indicated that thiol鈥搚ne nanocomposites may be useful as durable film or fiber SERS probes. Properties of the nanocomposites were evaluated using various techniques including UV鈥搗is spectroscopy, 渭-Raman spectroscopy, dynamic mechanical analysis, differential scanning calorimetry, thermogravimetric analysis, and transmission electron microscopy.